Pairwise Alignments

Query, 649 a.a., acetyl-coenzyme A synthetase from Vibrio cholerae E7946 ATCC 55056

Subject, 653 a.a., acetate--CoA ligase (RefSeq) from Dinoroseobacter shibae DFL-12

 Score =  855 bits (2210), Expect = 0.0
 Identities = 411/647 (63%), Positives = 495/647 (76%), Gaps = 5/647 (0%)

Query: 6   IYPVKQNIKAHTHADNDTYLAMYQQSIKDPEGFWSEHGKIVDWIKPFTKVKHTSFDPGHI 65
           +Y    +   + H D+  Y  MY  S+ DPEGFW EHG+ +DWIKP+TKVK TSF    +
Sbjct: 8   VYTPSADFVKNAHIDSSKYSEMYAASVSDPEGFWGEHGRSLDWIKPYTKVKDTSFAHDDV 67

Query: 66  DIRWFEDGTLNVSANCIDRHLATRGDQVAIIWEGDDPTQD-KTLTYKQLHQEVCRFANAL 124
            +RWFEDGTLNV+ANCIDRHLATRGDQ AII+E DDP +  + +TY++LH++VC+ +N L
Sbjct: 68  HVRWFEDGTLNVAANCIDRHLATRGDQTAIIFEPDDPAEPAQHITYRELHRQVCKLSNVL 127

Query: 125 KEQGVRKGDVVCIYMPMVPEAAVAMLACTRIGAVHTIVFGGFSPEALAGRIIDSNAKLVI 184
           ++ GVRKGD V +YMPM+PEAA AMLAC RIGA+H+IVF GFSP+AL+ RI  ++A+L+I
Sbjct: 128 EDLGVRKGDRVILYMPMIPEAAYAMLACARIGAIHSIVFAGFSPDALSARINGADARLLI 187

Query: 185 TADEGVRGGRAVPLKKNVDEALCNPEVKNISKVMVLKRTGGNVAWHEHRDIWWHEATAKA 244
           TAD   RGGR  PLK N D AL +   ++  K++V+KRTGG   W + RD  +HE   +A
Sbjct: 188 TADYAPRGGRQTPLKSNADAALLH--TRDDVKMLVVKRTGGQTTWVDGRDFDYHELMLEA 245

Query: 245 SDNCPPEEMKAEDPLFILYTSGSTGKPKGVLHTTGGYLVYATMTFKYVFDYQPNEVFWCT 304
            +   P E++AE PLFILYTSGSTG+PKGV+H++GGYL+YA MT KYVFD    +V+WCT
Sbjct: 246 DEVQHPVEVEAEHPLFILYTSGSTGQPKGVVHSSGGYLLYAAMTQKYVFDVHEGDVYWCT 305

Query: 305 ADVGWITGHSYLVYGPLANGAKTILFEGVPNYPTTARMSEVVDKHKVNILYTAPTAIRAL 364
           ADVGW+TGHSY+VYGPLANG  T++FEGVP YP  +R  +V DKHKV   YTAPTAIRAL
Sbjct: 306 ADVGWVTGHSYIVYGPLANGGTTVMFEGVPTYPDASRFWQVCDKHKVTQFYTAPTAIRAL 365

Query: 365 MAKGDEAIKGTSRDSLRIMGSVGEPINPEAWEWYYRTIGNEKSPIVDTWWQTETGGILIT 424
           MAKG E ++     SLR++G+VGEPINPEAW WY   +G  + PIVDTWWQTETGG L+T
Sbjct: 366 MAKGPEFVETCDLSSLRVLGTVGEPINPEAWNWYNDLVGKGRCPIVDTWWQTETGGHLLT 425

Query: 425 PLPGATALKPGSATRPFFGVQPALVD--NMGEIVEGATEGNLVLLDSWPGQMRTVYGDHD 482
           PLPGA A KPGSAT PFFGVQP ++D  +  EI E   EG L L DSWPGQMRTVYGDH+
Sbjct: 426 PLPGAIATKPGSATLPFFGVQPVVLDPHSGAEITETECEGVLCLKDSWPGQMRTVYGDHE 485

Query: 483 RFEQTYFSTFKGMYFTGDGARRDEDGYYWITGRVDDVLNVSGHRMGTAEIESALVAFNKI 542
           RF +TYFS +KG YF+GDG RRD DGYYWITGRVDDV+NVSGHRMGTAE+ESALVA  K+
Sbjct: 486 RFVKTYFSDYKGYYFSGDGCRRDADGYYWITGRVDDVINVSGHRMGTAEVESALVAHAKV 545

Query: 543 AEAAVVGVPHDIKGQAIYAYITLNDGVYPSAELHKEVKDWVRKEIGAIATPDVLHWTDAL 602
           AEAAVVG PHDIKGQ IY Y+TL +G  PS EL KE++ WVR EIG IA PD++ W   L
Sbjct: 546 AEAAVVGYPHDIKGQGIYCYVTLMNGEEPSEELRKELRTWVRTEIGPIAAPDLIQWAPGL 605

Query: 603 PKTRSGKIMRRILRKIATGDTSNLGDTSTLADPSVVDRLIAEKAQLK 649
           PKTRSGKIMRRILRKIA  D   LGDTSTLADPSVV+ LI  +   K
Sbjct: 606 PKTRSGKIMRRILRKIAEDDFGALGDTSTLADPSVVEDLIENRMNKK 652