Pairwise Alignments

Query, 429 a.a., phosphoribosylamine--glycine ligase from Vibrio cholerae E7946 ATCC 55056

Subject, 422 a.a., Probable phosphoribosylamine--glycine ligase PurD (GARS) (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase) (5'-phosphoribosylglycinamide synthetase) from Mycobacterium tuberculosis H37Rv

 Score =  301 bits (770), Expect = 3e-86
 Identities = 180/429 (41%), Positives = 248/429 (57%), Gaps = 21/429 (4%)

Query: 1   MQVLIIGSGGREHALAWKVAQNPQVDTIYVAPGNAGTALEHKVQNVNIGITDIPALVAFA 60
           ++VL+IGSG REHAL   + ++PQV  + VAPGNAGTA     +  ++ IT   A+VA A
Sbjct: 1   VRVLVIGSGAREHALLLALGKDPQVSGLIVAPGNAGTA--RIAEQHDVDITSAEAVVALA 58

Query: 61  QDKAIELTIVGPEAPLVIGVVDAFRAAGLPIFGPTQGAAQLEGSKAFTKDFLARHNIPTA 120
           ++   ++ ++GPE PLV+GV DA RAAG+  FGP + AA++EGSKAF KD +A   + TA
Sbjct: 59  REVGADMVVIGPEVPLVLGVADAVRAAGIVCFGPGKDAARIEGSKAFAKDVMAAAGVRTA 118

Query: 121 AYANFTEIEPALAYVREKGAPI-----VVKADGLAAGKGVIVAMTLQEAEDAIQDMLAGN 175
                       A +   G P      VVK D LAAGKGV+V      A         G 
Sbjct: 119 NSEIVDSPAHLDAALDRFGPPAGDPAWVVKDDRLAAGKGVVVTADRDVAR------AHGA 172

Query: 176 AFGSAGSRVVVEEFLDGEEASFIVMVDGENVLPMATSQDHKRVGDADTGPNTGGMGAYSP 235
           A   AG  V++E +LDG E S   +VD   V+P+  +QD KRVG+ DTG NTGGMGAY+P
Sbjct: 173 ALLEAGHPVLLESYLDGPEVSLFCVVDRTVVVPLLPAQDFKRVGEDDTGLNTGGMGAYAP 232

Query: 236 APVVTQDVHDRVMREVIDPTVRGMAAEGNTYTGFLYAGLMIDSTGAPKVIEYNCRFGDPE 295
            P +  +++  V+  +++P    +   G+++ G LY GL I + G P V+E+NCRFGDPE
Sbjct: 233 LPWLPDNIYREVVSRIVEPVAAELVRRGSSFCGLLYVGLAITARG-PAVVEFNCRFGDPE 291

Query: 296 TQPIMMRLQSDLVELCQAAIAGKL-DQVESKWDPRASIGVVLAAGGYPGDYAKGEVISGL 354
           TQ ++  L+S L +L  AA  GKL D  E +W    ++ VVLAA  YPG    G+V+ G 
Sbjct: 292 TQAVLALLESPLGQLLHAAATGKLADFGELRWRDGVAVTVVLAAENYPGRPRVGDVVVG- 350

Query: 355 PTQESAGQKVFHAGTETQGD-QVVTNGGRVLCATALGNTVLEAQQRAYQLADQIHWNGMF 413
               S  + V HAGT  + D  +V++GGRVL     G  +  A+  AY++   I   G  
Sbjct: 351 ----SEAEGVLHAGTTRRDDGAIVSSGGRVLSVVGTGADLSAARAHAYEILSSIRLPGGH 406

Query: 414 CRRDIGYRA 422
            R DIG RA
Sbjct: 407 FRSDIGLRA 415