Pairwise Alignments

Query, 455 a.a., MBL fold hydrolase from Vibrio cholerae E7946 ATCC 55056

Subject, 517 a.a., Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain from Pseudomonas stutzeri RCH2

 Score =  392 bits (1008), Expect = e-113
 Identities = 219/504 (43%), Positives = 300/504 (59%), Gaps = 69/504 (13%)

Query: 19  EVVHHGGKASVTGSCHELRADGQ-ALLIDCGLFQG----ADERP----LAVEFALGHVDA 69
           ++ HHG K  VTGSCH+L  D   +LL+DCGLFQG    +D R     L +EF+L  V A
Sbjct: 5   DIEHHGAKDGVTGSCHQLHMDASHSLLVDCGLFQGNETSSDGRAATGRLDIEFSLRTVQA 64

Query: 70  LILTHAHIDHIGRLPWLLAAGLKQPIYSTAATAELVPLMLEDGLKLQLGMSPKQSERVLT 129
           L++TH HIDH+GR+P+LLAAG K PIY +  +A+L+P++LED  KL      K  ER L 
Sbjct: 65  LVVTHVHIDHVGRIPYLLAAGYKGPIYCSEPSAKLLPIVLEDAFKLGFSRDQKAVERYLK 124

Query: 130 EVRRLLRVQDYQKWFAVQPKRADSLWVRFQPAGHILGSAYVEI-----RRPNGEVVVFSG 184
            V + LR   YQ+W  +         VR Q AGHILGSAYVEI          + +VFSG
Sbjct: 125 LVEQRLRPLPYQRWSTLLETEELIARVRLQRAGHILGSAYVEIDLTYPTSGESQRIVFSG 184

Query: 185 DLGPSHTPLLPDPQSPERADYLFIETTYGDKQHEDVQSRGQRLRAMIERSLTDGGAILIP 244
           DLG +H PLL  P+SPERAD L +E+TYGD+ HED  SR QRL A+IE +L D G +LIP
Sbjct: 185 DLGAAHAPLLMPPESPERADILVLESTYGDRLHEDRTSRRQRLEAVIEHALQDQGTVLIP 244

Query: 245 AFSVGRTQELLFDIEQLIFSQQ-------------------------------------- 266
           AFS+GRTQELL+++E++I S+Q                                      
Sbjct: 245 AFSIGRTQELLYELEEIIHSKQQVSTDQSSLPADERARGGIESAGAPHSHSPLSSEERAR 304

Query: 267 IDAN--------------LPIILDSPMAQRVTRSYRRFKQLWGREAKARLQMHRHPLAFE 312
           ++ N              LPIILDSP+A R T +YR  +  W +EA+ R++  R+PLAF+
Sbjct: 305 VERNSDNAHGQLETDWPRLPIILDSPLATRFTEAYRSLQPYWNQEARERVEGGRNPLAFD 364

Query: 313 QCITVEDHRTHERLVNRLASTGEAAIVVAASGMCQGGRIMDYLKALLPDKRTDLILAGFQ 372
             I ++ H  H  +VN L  T   AIV+A +GMC GGRI++YLKA+L D R D++  G+Q
Sbjct: 365 NLIMIDSHADHIAVVNHLTQTARPAIVIAGNGMCSGGRIVNYLKAMLHDPRHDVLFVGYQ 424

Query: 373 AEGTLGRSIQSGQPS---VWIEGTEVEVNAHIHTMSGYSAHADKADLLRFITGIPEKPKQ 429
           A+GT G++IQ   P    V ++G   ++ A + ++ GYSAHAD+  L+ F+TG+ E P +
Sbjct: 425 AQGTPGQAIQQYGPKGGYVDLDGERFDIRARVTSIGGYSAHADQKGLVEFVTGMREWPTK 484

Query: 430 VHLIHGEAPAKQAFAAELTQLGYS 453
           + ++HGE  A+QA    L Q  Y+
Sbjct: 485 IGVVHGEHGARQALIKVLQQRYYA 508