Pairwise Alignments
Query, 1036 a.a., multidrug resistance protein from Vibrio cholerae E7946 ATCC 55056
Subject, 1055 a.a., multidrug efflux RND transporter permease subunit from Burkholderia phytofirmans PsJN
Score = 544 bits (1402), Expect = e-158
Identities = 336/1026 (32%), Positives = 545/1026 (53%), Gaps = 27/1026 (2%)
Query: 1 MRFTDVFIKRPVLAVSISFLIVLLGLQAIFKMQVREYPEMTNTVITVSTGYYGASADLIQ 60
M+F FI RP+ A +S ++V+ G A+F + + ++P++ ITVS Y GASA+++
Sbjct: 1 MKFAHFFIDRPIFASVLSIILVVAGTVAMFNLPIAQFPDIAPPTITVSATYPGASAEVVA 60
Query: 61 GFITQPLEQAVAQADNIDFM-TSQSVLGRSTITVTMKLNTDPNAALSDVLAKTNSVRSQL 119
+ PLEQ V ADN+ +M +S S G T+T + TDP+ A DV + N L
Sbjct: 61 QNVAAPLEQQVNGADNMMYMNSSSSSTGNMTLTAYFNIGTDPSLAQVDVQNRVNLALPTL 120
Query: 120 PKEAEDPTVTMSTGSTTAVLYIGFTS--NELASSQITDYLERVVNPQLYAVNGVSSIDLY 177
P V++ S+ ++ I S N S + +Y V L + G + ++
Sbjct: 121 PDSVTAQGVSVQKRSSAFMMVIAIYSPDNAFDQSYVANYANVYVLDALKRIPGANQASIF 180
Query: 178 GGMKYALRVWLDPAKMAALNLSAADVMSILNANNYQSATGQAIGEFVLYNGSADT----- 232
G YA+R+W+ P +MA L+++ ADV ++ N Q + G+ +G+ T
Sbjct: 181 GSADYAMRIWIKPDRMAKLSITVADVQQAISNQNQQFSAGR-LGQSPTNAPVQQTFPVAT 239
Query: 233 --QVSTVEDLESLVVKAEKGTVT--RLGDIAKVTLAKSHDTYRASANGREAVVAAINAAP 288
+++ D ++++++A G + R+ DI L + R NG+ A + A+ P
Sbjct: 240 KGRMTKPADFDNIILRAGSGDASTIRIKDIGHAELGAKDYSLRGRYNGKTATLIAVYQQP 299
Query: 289 SANPINIAKDVLEMLPELQKNMPSNIEMNVLYDSTVAINESIHEVIKTIVEAALIVLVVI 348
AN + +AK V L +LQK P ++ V D+T + ESI EVI T+ +A ++V++V+
Sbjct: 300 GANALQVAKQVHATLEQLQKAFPPGLKYEVALDTTEFVQESIGEVIHTLRDAVILVILVV 359
Query: 349 TLFLGSLRAVLIPIVTIPLSLIGVAMVMQMMGFSWNLMTLLAMVLAIGLVVDDAIVVLEN 408
+FL S RA L+P++ +P+S++G + M + GFS N++TL MVLAIG+VVDDAIVV+EN
Sbjct: 360 FIFLQSFRATLVPLLAVPVSILGAFIGMLVFGFSVNMLTLFGMVLAIGIVVDDAIVVIEN 419
Query: 409 VDRHIKE-GESPFRAAIIGTREIAIPVIAMTLTLGAVYAPIALMGGITGSLFKEFALTLA 467
V+R++ E G P AA E+ PVIA+ L L AV+ P+A + GITG L+K+FA+T+A
Sbjct: 420 VERNMTEFGLPPKEAAKHAMDEVTGPVIAIVLVLLAVFIPVAFLSGITGQLYKQFAVTIA 479
Query: 468 GSVFVSGIVALTLSPMMCSKMLK-ANEAPNKFELKVHHLLDRMTARYERMLTAVMAHRPV 526
SV +SGIVALTLSP + + +LK N+F L + DR+T Y R + + +
Sbjct: 480 VSVVISGIVALTLSPALAAILLKPGTHKKNRFFLWFNKRFDRLTQGYGRAVQLAIRRVAL 539
Query: 527 VIAFAFIVFASLPMLFKFIPSELAPSEDKGVIMLMGTGPSNANLDYLANTMDDVNKILSD 586
I + A+ LFK IPS P+ED+G ++ P A+LD N + +
Sbjct: 540 SILLIVAMVAATAGLFKHIPSSFLPTEDQGYLLGAVVLPDAASLDRTGNLSQRAEQWFAK 599
Query: 587 QPEVQFAQVFTGVP------NSNQAFGIASMVPWSQREASQATVTNRVGTLVQDIPGMA- 639
QP V+ G SN ++ + R T + + + G
Sbjct: 600 QPAVKSVAAPIGYSLIDSQYKSNAGTLFITLKGFKDR-GENGTAQDLIRDANKAFSGYTD 658
Query: 640 --VTAFQMPELPGAGSGLPIQFVI--TTPSNFESLFTIATDVLTEVKANPMFVYSDLDLN 695
V P +PG G+ +F + T ++++L + + + NP + +N
Sbjct: 659 GVVVPLNPPSIPGLGTTGGFEFWLQSTGDGSYQNLEEKVRAFIAKARQNPALRGVNSTIN 718
Query: 696 FDSATMKINIDKDKAGAYGVTMQDIGITLSTMMADGYVNRIDLNGRSYEVIPQVERKWRL 755
+S + + +D+++A + GV +QDI L TM YV++ + R ++VI Q E ++R
Sbjct: 719 TNSRQLLVEVDRERAESLGVPIQDIYAALQTMFGSSYVSQFPKSSRLFQVIVQAEPQYRT 778
Query: 756 NPESMNSYYVRAADGKVIPLGSLVTIDVVAEPRSLPHFNQLNSATVGAVPAPGTAMGDAI 815
P+ + YVR G ++P+ ++ T+ V + FN +A + APG + G++I
Sbjct: 779 QPDDIQQLYVRNRSGDMVPIKAVTTVRFVPGADIVTRFNNFPAAKITGDAAPGHSSGESI 838
Query: 816 NWFENLASSKLPKGYSHDYMGEARQYVTEGSALYATFGLALAIIFLVLAIQFESLRDPLV 875
E +A L +GYS+ + G+A + GS FG AL ++FL+LA Q+E P+
Sbjct: 839 AAMEQIAHEVLGEGYSYAWSGQAYEEKQAGSTAILVFGFALLMVFLILAAQYEKWSLPIG 898
Query: 876 IMVSVPLAICGALIALAWGTATMNIYSQVGLITLVGLITKHGILICEVAKEEQLHNKLSR 935
++++VP AI GALI + ++Y Q+GL L+ L K+ ILI E A E + LS
Sbjct: 899 VLLAVPFAIFGALIGILLRGMEDDVYFQIGLTVLIALAAKNAILIFEFAVEMREKEALSP 958
Query: 936 IEAVMHAAKVRLRPILMTTAAMIAGLIPLMYATGAGAAQRFSIGIVIVSGLAIGTLFTLF 995
+A + AAK+RLRPI+MT+ A I G +PL A+GA AA R S+G ++ G+ T+ LF
Sbjct: 959 YDAALKAAKLRLRPIIMTSLAFILGCVPLAIASGASAASRRSLGTGVIFGMLGATVIALF 1018
Query: 996 VLPVIY 1001
+P+ +
Sbjct: 1019 FIPMFF 1024
Score = 70.9 bits (172), Expect = 5e-16
Identities = 80/403 (19%), Positives = 158/403 (39%), Gaps = 25/403 (6%)
Query: 620 SQATVTNRVGTLVQDIPGMAVTAFQMPELPGAGSGLPIQFVITTPSNFESLFTIAT---- 675
+Q V NRV + +P +VTA Q + S + I +P N +A
Sbjct: 105 AQVDVQNRVNLALPTLPD-SVTA-QGVSVQKRSSAFMMVIAIYSPDNAFDQSYVANYANV 162
Query: 676 ---DVLTEVK-ANPMFVYSDLDLNFDSATMKINIDKDKAGAYGVTMQDIGITLSTM---M 728
D L + AN ++ D M+I I D+ +T+ D+ +S
Sbjct: 163 YVLDALKRIPGANQASIFGSADY-----AMRIWIKPDRMAKLSITVADVQQAISNQNQQF 217
Query: 729 ADGYVNRIDLNGRSYEVIPQVERKWRLNPESMNSYYVRAADG--KVIPLGSLVTIDVVAE 786
+ G + + N + P + P ++ +RA G I + + ++ A+
Sbjct: 218 SAGRLGQSPTNAPVQQTFPVATKGRMTKPADFDNIILRAGSGDASTIRIKDIGHAELGAK 277
Query: 787 PRSLP-HFNQLNSATVGAVPAPGT---AMGDAINWFENLASSKLPKGYSHDYMGEARQYV 842
SL +N + + PG + ++ P G ++ + ++V
Sbjct: 278 DYSLRGRYNGKTATLIAVYQQPGANALQVAKQVHATLEQLQKAFPPGLKYEVALDTTEFV 337
Query: 843 TEG-SALYATFGLALAIIFLVLAIQFESLRDPLVIMVSVPLAICGALIALAWGTATMNIY 901
E + T A+ ++ LV+ I +S R LV +++VP++I GA I + ++N+
Sbjct: 338 QESIGEVIHTLRDAVILVILVVFIFLQSFRATLVPLLAVPVSILGAFIGMLVFGFSVNML 397
Query: 902 SQVGLITLVGLITKHGILICEVAKEEQLHNKLSRIEAVMHAAKVRLRPILMTTAAMIAGL 961
+ G++ +G++ I++ E + L EA HA P++ ++A
Sbjct: 398 TLFGMVLAIGIVVDDAIVVIENVERNMTEFGLPPKEAAKHAMDEVTGPVIAIVLVLLAVF 457
Query: 962 IPLMYATGAGAAQRFSIGIVIVSGLAIGTLFTLFVLPVIYSYL 1004
IP+ + +G + I + I + L + P + + L
Sbjct: 458 IPVAFLSGITGQLYKQFAVTIAVSVVISGIVALTLSPALAAIL 500