Pairwise Alignments

Query, 645 a.a., phosphomethylpyrimidine synthase from Vibrio cholerae E7946 ATCC 55056

Subject, 721 a.a., thiamin biosynthesis protein ThiC (NCBI ptt file) from Shewanella oneidensis MR-1

 Score =  927 bits (2395), Expect = 0.0
 Identities = 470/676 (69%), Positives = 532/676 (78%), Gaps = 39/676 (5%)

Query: 2   SNRKQARLEAKRFIDTLSVEPYPNSQKSYLLGSRPDIRVPVREITLSDTLVGGSKDAPIF 61
           +NR+ AR +A+ FIDTL    +PNSQK YL GSR D+RV +R+I  +DT +GG   AP  
Sbjct: 19  TNRRVARAQAQAFIDTLKPLQHPNSQKLYLQGSRADLRVGMRQILQTDTRIGGRAAAPNV 78

Query: 62  EPNEPICVYDTSGVYTDPSHDIDLYKGLPKLREEWIEERRDTHILPSMSSHFARERLADE 121
           E N PI VYD +G Y+DP+  I++ +GL KLR  WI ER+DT +L   +S F ++RL D+
Sbjct: 79  EKNPPIPVYDCAGPYSDPAAQINVRQGLAKLRLPWIIERQDTEVLDCTTSDFTQQRLKDD 138

Query: 122 TLDELRY----GHLPRIRRAMGQHRVTQLHYARQGIITPEMEFVAIRENSRRLAHQDPSL 177
            LD LR+      + R RRA+   RV+QLHYARQGIITPEME+VAIREN      QD  L
Sbjct: 139 GLDHLRFEAGSSAIIRPRRALPGKRVSQLHYARQGIITPEMEYVAIRENMALADVQDEIL 198

Query: 178 LQQHAGQNFGAHLPDLITPEFVRREIAEGRAIIPCNINHPESEPMIIGRNFLVKVNANIG 237
            ++  G++FGA +   ITPEFVR EIA GRAIIP NINHPE+EPM IGRNFLVKVNANIG
Sbjct: 199 NRRGQGESFGAVIGKPITPEFVRDEIARGRAIIPLNINHPEAEPMTIGRNFLVKVNANIG 258

Query: 238 NSSVSSSIEEEVEKLVWATRWGADTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALE 297
           NS+V+SSIEEEVEKLVW+TRWGADTVMDLSTGR IHETREWI+RNSPVPIGTVP+YQALE
Sbjct: 259 NSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWIIRNSPVPIGTVPIYQALE 318

Query: 298 KVNGVAENLTWEVMRDTLLEQAEQGVDYFTIHAGLLLRYVPMTAKRVTGIVSRGGSIIAK 357
           KVNGVAE+LTWEV RDTL+EQAEQGVDYFTIHAG+LLRYVPMTAKRVTGIVSRGGSI+AK
Sbjct: 319 KVNGVAEHLTWEVFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRVTGIVSRGGSIMAK 378

Query: 358 WCLSHHQENFLYTHFREICEICAQYDVALSLGDGLRPGSIADANDEAQFAELRTLGELTQ 417
           WCLSHHQENFLYTHFREICE+C  YDV+LSLGDG+RPGSIADANDEAQFAEL TLGEL  
Sbjct: 379 WCLSHHQENFLYTHFREICELCVAYDVSLSLGDGMRPGSIADANDEAQFAELETLGELVN 438

Query: 418 IAWEYDVQVMIEGPGHVPMHLIKANMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSGIG 477
           IAWEYDVQ +IEGPGH+PM LIK NMD+QL HC EAPFYTLGP  TDIAPGYDH TSGIG
Sbjct: 439 IAWEYDVQTIIEGPGHIPMQLIKENMDKQLIHCAEAPFYTLGPQITDIAPGYDHFTSGIG 498

Query: 478 AAMIGWFGCAMLCYVTPKEHLGLPNKEDVKTGLITYKLAAHAADLAKGHPGAQIRDNALS 537
           AAMI W+GCAMLCYVTPKEHLGLPNK+DVK GLI YK+AAHAAD+AKGHPGAQIRDNALS
Sbjct: 499 AAMIAWYGCAMLCYVTPKEHLGLPNKQDVKQGLIAYKIAAHAADIAKGHPGAQIRDNALS 558

Query: 538 KARFEFRWEDQFNLALDPVTARAFHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYA 597
           KARFEFRWEDQ+NL LDP TARA+HDE+LPQES KVAHFCSMCGPKFCSMKI+Q+VRDYA
Sbjct: 559 KARFEFRWEDQYNLGLDPDTARAYHDESLPQESAKVAHFCSMCGPKFCSMKITQDVRDYA 618

Query: 598 NN-------QTLDTTVIDLVMPAESIQ----------------------------LAMQD 622
            +       Q+L       + P  S+Q                             AM  
Sbjct: 619 ASLEADAKAQSLAAETDGALAPLGSVQQVKSGHSELSHIDAELNYIAVKTQDELTAAMAQ 678

Query: 623 KSREFLASGAELYHPL 638
           KS EF A GA+LY PL
Sbjct: 679 KSAEFAALGAKLYLPL 694