Pairwise Alignments

Query, 190 a.a., DNA topoisomerase from Vibrio cholerae E7946 ATCC 55056

Subject, 865 a.a., type I DNA topoisomerase from Rahnella sp. WP5

 Score = 38.9 bits (89), Expect = 3e-07
 Identities = 35/133 (26%), Positives = 64/133 (48%), Gaps = 14/133 (10%)

Query: 24  CPQCGAALQLRHGKHGPFLG-CTAYPECDYIKPLHQNDGHIIKELG--VPCPECGHELVL 80
           C +CG A+      +   L  C   PECD  + + + +  I    G  V C +CG E+ L
Sbjct: 662 CVKCGTAMDSYLIDNQRKLHVCGNNPECDGYE-IEEGEFRIKGYDGPIVECEKCGSEMHL 720

Query: 81  RQGRYGMFIGCSHYPQCHHIESM-----DSPSQEE--TSPDILCPECGKGHLIERKSRFG 133
           + GR+G ++GC++  +C +   +      +P +E+    P++ C E    + + R    G
Sbjct: 721 KMGRFGKYMGCTN-DECKNTRKILRNGDVAPPKEDPVPLPELPC-EKSDAYFVLRDGAAG 778

Query: 134 KLFYACDAYPKCK 146
            +F A + +PK +
Sbjct: 779 -VFLAANTFPKSR 790



 Score = 34.3 bits (77), Expect = 6e-06
 Identities = 36/141 (25%), Positives = 58/141 (41%), Gaps = 24/141 (17%)

Query: 15  HEHALQSSPCPQCGAALQLRHGKHGPFLGCTAY--PECDYIKPLHQ--NDGHIIKELGVP 70
           ++  L S  CP CG  + +R    G FLGC+ Y  P  +  K       D  ++  L   
Sbjct: 590 NQMVLTSIECPTCGRPMGIRTASTGVFLGCSGYALPPKERCKTTINLIADAEVLNILEGD 649

Query: 71  ------------CPECGHEL--VLRQGRYGMFIGCSHYPQC--HHIESMDSPSQEETSPD 114
                       C +CG  +   L   +  + + C + P+C  + IE  +   +    P 
Sbjct: 650 EAEANALRAKRRCVKCGTAMDSYLIDNQRKLHV-CGNNPECDGYEIEEGEFRIKGYDGPI 708

Query: 115 ILCPECG-KGHLIERKSRFGK 134
           + C +CG + HL  +  RFGK
Sbjct: 709 VECEKCGSEMHL--KMGRFGK 727



 Score = 34.3 bits (77), Expect = 6e-06
 Identities = 35/146 (23%), Positives = 58/146 (39%), Gaps = 36/146 (24%)

Query: 69  VPCPECGHELVLRQGRYGMFIGCSHY-----PQCH-------HIESMDSPSQEETSPDIL 116
           + CP CG  + +R    G+F+GCS Y      +C          E ++    +E   + L
Sbjct: 597 IECPTCGRPMGIRTASTGVFLGCSGYALPPKERCKTTINLIADAEVLNILEGDEAEANAL 656

Query: 117 -----CPECG---KGHLIERKSRFGKLFYACDAYPKC--------KFALN--SKPIAQAC 158
                C +CG     +LI+ + +     + C   P+C        +F +     PI + C
Sbjct: 657 RAKRRCVKCGTAMDSYLIDNQRK----LHVCGNNPECDGYEIEEGEFRIKGYDGPIVE-C 711

Query: 159 AQCGFTVMVEKKSAAGMRYQCANRQC 184
            +CG + M  K    G    C N +C
Sbjct: 712 EKCG-SEMHLKMGRFGKYMGCTNDEC 736



 Score = 24.3 bits (51), Expect = 0.007
 Identities = 11/31 (35%), Positives = 14/31 (45%)

Query: 19  LQSSPCPQCGAALQLRHGKHGPFLGCTAYPE 49
           L   PC +  A   LR G  G FL    +P+
Sbjct: 758 LPELPCEKSDAYFVLRDGAAGVFLAANTFPK 788