Pairwise Alignments

Query, 728 a.a., MrcA2 penicillin-binding protein from Sinorhizobium meliloti 1021

Subject, 835 a.a., penicillin-binding protein 1A from Vibrio cholerae E7946 ATCC 55056

 Score =  379 bits (974), Expect = e-109
 Identities = 254/733 (34%), Positives = 379/733 (51%), Gaps = 56/733 (7%)

Query: 3   LIGYIFGITSAALVGIFGIGAVYLWEVANDLPDHRKLAEWEPALMTRFYAYDGTPIAEYA 62
           LI  I G+T+     IFG    + + V +DLPD   L + +     + ++ DG  IA++ 
Sbjct: 22  LICIILGVTT-----IFG----FYFYVKSDLPDVATLRDVQLQTPMQVFSQDGKLIAQFG 72

Query: 63  RERRLYLPIAAIPERVKAAFLSAEDKSFYSHSGIDVLSVVKAAWSNAVNLSSGQRLIGAS 122
            +RR+ L +  +P+ +  A ++ ED  +Y H G D + + +AA++    L+SG    GAS
Sbjct: 73  EKRRIPLKLEEMPKELIEAVIATEDSRYYEHYGFDPIGITRAAFAV---LASGSASQGAS 129

Query: 123 TITQQLAKNFLLSSDRTLRRKIKEAVLSIRIERSLSKDRILELYLNDIYLGLGAYGIAAG 182
           TITQQLA+NF LS+++ + RK+KE  ++I IE+ LSK  ILELYLN IYLG  +YG+ A 
Sbjct: 130 TITQQLARNFFLSNEKKVMRKVKEIFIAIHIEQLLSKQEILELYLNKIYLGYRSYGVGAA 189

Query: 183 ALTYFEKSVSELTVAEAAYLAALPKGPNNYNPHRHPERAVSRRNWVIGQMQRNGFVSAAQ 242
           A  YF K V +LT+ E A +A LPK P+  NP    ERA +RRN V+ +M    +++ A+
Sbjct: 190 AQAYFGKEVKDLTLGEIALIAGLPKAPSTMNPIYSVERATNRRNVVLQRMLDEKYITKAE 249

Query: 243 ASNMMARPLGVKPQAKNPVMAEANYFVEEVRREVAGQYGEAALYDGGLSVRTTLDPTLQA 302
                A P+  K      +   A Y  E  R  +  +YGE A Y  G++V TT+D  LQ 
Sbjct: 250 YDAARAEPVLPKYHGAE-IELNAPYVAEIARAWMVERYGEEAAYTSGMNVYTTVDSKLQR 308

Query: 303 AALMALRAGLVDYDQARGFRGPVAHIDISGD--WATA-----LAKHETFTDMKEWQLAVV 355
           AA  A    L+ YD+  G+RG    +       W++      L+   T+ DM     A V
Sbjct: 309 AANQAAINNLLAYDERHGYRGAEKELWQVNQPAWSSTQLSEYLSNEPTYGDMFP---AAV 365

Query: 356 LSCSDAGVGIGLRRAKLGPEHSPTSPETGLIGRNTMRWALKLAAGGKIRQV-DSIDKVLS 414
           LS  +    + ++           S     I    M WA +     +   +  S ++ L+
Sbjct: 366 LSVEEKSAQVWVK-----------SYGVQTIAWEDMNWARRFINDDRQGPLPKSANEFLA 414

Query: 415 PGDVIYV-----EKVGNGYLLRQIPEVQGAIVSMDPNTGRVLASVGGFSFAQSRFNRATQ 469
            G  I+V     +     + L Q+P    A V+M+P  G V A VGGF+F  ++FNRATQ
Sbjct: 415 AGQQIWVRPRTQDGAITAWKLTQVPNANTAFVAMNPENGAVTALVGGFNFVHNKFNRATQ 474

Query: 470 ASRQPGSAFKPFVYAAALDTGYTPATLVMDAPFSMPD-GAGRLWKPKNYDGKFGGPSTLR 528
           + RQ GS+ KPF+Y+AAL+ G T ATL+ DAP +  D   G  W+PKN    + GP+ LR
Sbjct: 475 SVRQVGSSIKPFIYSAALNKGLTLATLINDAPINQWDESQGTAWRPKNSPPTYTGPTRLR 534

Query: 529 TGLEMSRNLMTVRLARHLGMDLVAEYGRAFGL-YDKLAPYLPMSLGAGETTLTRLVSAYA 587
            GL  S+N+M VR+ R +G+D   EY   FG   D+L     ++LGAG  T  ++   ++
Sbjct: 535 IGLAQSKNVMAVRVLREVGLDETREYLTRFGFKLDQLPRSETIALGAGSLTPVQMAQGFS 594

Query: 588 VLANGGHAVQPSMIDRIQDRHGRTIFRHDDR-ACDR-CNATRWLHQEEPVLRDTRKQVLD 645
           V AN G+ V+P  I R+++  G   F  + +  C R C++      E+        +V+ 
Sbjct: 595 VFANNGYFVEPFYISRVENPFGNIEFSAEPKVVCHRECSSELDEFAEQDAASPYAPKVIS 654

Query: 646 PMTAYQVTSMLRGVV-----------ERGTAHRVSQL-GAPVAGKTGTTNDEKDVWFVGY 693
              A+    ML   +             GT  R   L    + GKTGTTND KD W+ GY
Sbjct: 655 EQNAFLTREMLYSNIWGGGEWSSDTGWNGTGWRAQALKRRDIGGKTGTTNDSKDAWYNGY 714

Query: 694 TPTLVTGIFMGYD 706
            P +V   ++G+D
Sbjct: 715 APGIVGVAWVGFD 727