Pairwise Alignments
Query, 2542 a.a., erythronolide synthase (RefSeq) from Shewanella amazonensis SB2B
Subject, 2624 a.a., beta-ketoacyl synthase (RefSeq) from Shewanella sp. ANA-3
Score = 2460 bits (6376), Expect = 0.0
Identities = 1437/2670 (53%), Positives = 1758/2670 (65%), Gaps = 208/2670 (7%)
Query: 6 TQDAQDLRLNKRLKDTPIAIVGMASLFANSRYLNDFWDLICDKIDAITEVPADRWQIDDY 65
T + D RLNKRLKD PIAIVGMAS+FANSRYLN FWDLICDKIDAIT+VP W IDDY
Sbjct: 12 TDEKADKRLNKRLKDMPIAIVGMASIFANSRYLNKFWDLICDKIDAITDVPESHWSIDDY 71
Query: 66 FDADKRSPDKSYCKRGGFIPQVDFNPMEFGLPPNILELTDSAQLLSLIVAKEVLEDAGVS 125
+DADK DKSYCKRGGF+P+VDFNPMEFGLPPNILELTDS+QLLSL+VAKEVL+DA +
Sbjct: 72 YDADKSKADKSYCKRGGFMPEVDFNPMEFGLPPNILELTDSSQLLSLVVAKEVLQDANLP 131
Query: 126 ENSAHDRDKIGITLGIGGGQKISQSLNARLQYPVLKKVFRESGISDADSEMLIRKFQDQY 185
++ +DRD+IGITLGIGGGQK+S SLNARLQYPVLKKVF+ SG+SD DSE+LI+KFQDQY
Sbjct: 132 DD--YDRDRIGITLGIGGGQKLSHSLNARLQYPVLKKVFKSSGLSDEDSELLIKKFQDQY 189
Query: 186 IHWEENSFPGSLGNVIAGRIANRFDLGGMNCVVDAACAGSLAAIRMALTELTEGRADMML 245
+HWEENSFPGSLGNVIAGRIANRFDLGGMNCVVDAACAGSLAA+RMALTELTEGR+DMM+
Sbjct: 190 VHWEENSFPGSLGNVIAGRIANRFDLGGMNCVVDAACAGSLAAMRMALTELTEGRSDMMI 249
Query: 246 TGGACTDNSAYMYMSFSKTPAFTVDEQIKPFDADSKGMMIGEGIGMVALKRLEDAERDGD 305
TGG CTDNS YMYMSFSKTPAFT +EQI+PFD DSKGMMIGEGIGMVALKRL+DAERDGD
Sbjct: 250 TGGVCTDNSPYMYMSFSKTPAFTTNEQIQPFDIDSKGMMIGEGIGMVALKRLDDAERDGD 309
Query: 306 KIYAVIKGVGASSDGKFKSIYAPRPEGQAKALRRAYDDAGFPAHTLGLMEAHGTGTAAGD 365
+IYAVIKGVGASSDGKFKSIYAPRPEGQAKAL RAYDDAGF HT+GL+EAHGTGTAAGD
Sbjct: 310 RIYAVIKGVGASSDGKFKSIYAPRPEGQAKALERAYDDAGFAPHTVGLIEAHGTGTAAGD 369
Query: 366 VAEFSGLSLVMGESSDETQHIALGSIKSQVGHTKSTAGTAGLIKAALALHHKVLPPTINV 425
VAEF+GL+ V + +++ QHIALGS+KSQVGHTKSTAGTAG+IKAALALHHKVLPPTINV
Sbjct: 370 VAEFNGLTSVFSKDNEQLQHIALGSVKSQVGHTKSTAGTAGVIKAALALHHKVLPPTINV 429
Query: 426 NKPNPKLNIEASPFYLSTETRPWLPRPDGTPRRAAVSSFGFGGTNFHLVMEEYQRDHGR- 484
++PNPKLNI SPFYL+TE RPW+ R D TPRRA +SSFGFGGTNFHLV+EEY+ +H R
Sbjct: 430 SQPNPKLNIAHSPFYLNTEARPWIQRSDDTPRRAGISSFGFGGTNFHLVLEEYRPEHARD 489
Query: 485 TPYRLRSTQVPLLFAAPSREALSNDLK-----ALCERLSNTEETFETLTAPFTLKGEPPK 539
YR RS LF A + AL +LK A + ++ F + L+ PP+
Sbjct: 490 DAYRQRSVAQSWLFTAADKTALLGELKTALQQATAAKAELSQAHFVAFAKSYALRELPPQ 549
Query: 540 AEWPRLGIVAANAKALKACLEDAIEKL-ATSSDDWH-TQDMSFRAQAMAK-NTRVAALFA 596
+ RLG +A + L+A L AI +L + S++ W +SFRAQA+ K N +VAALFA
Sbjct: 550 S--ARLGFIAKDYVQLQALLTQAIAQLESNSAESWQLPTGISFRAQALVKDNHKVAALFA 607
Query: 597 GQGSQYLGMGGELAMLYPEMRAEFIAADEVFHQRGYPGRHGTGELSSHVFPIPKFDSDAR 656
GQGSQYL MG E+A +PE+R +D+VF R G LSS ++PIP FD ++R
Sbjct: 608 GQGSQYLNMGLEIANNFPELRRHIHTSDKVFSDR------GEATLSSVLYPIPAFDDESR 661
Query: 657 KQDEEALTNTRIAQSAIGVVSMGQFEILKAAGLTPDAVAGHSFGELSALRAAGVIDQASY 716
K E ALTNT AQSAIG +SM Q+ +L AG PD +AGHSFGELSAL AAGVI Y
Sbjct: 662 KAQESALTNTLYAQSAIGALSMAQYALLTQAGFAPDMLAGHSFGELSALCAAGVISVDDY 721
Query: 717 YRLAFARGDAMASVPK----GKDAGTMAAVILPDASHRSTLDTLLTQHESVVIANHNSPT 772
+LAF RG AMA P+ DAG M AVIL + L Q + V IAN+NSPT
Sbjct: 722 IKLAFERGLAMAQSPQDADSSSDAGVMYAVILKQKQDIEAIKESLAQFDGVKIANYNSPT 781
Query: 773 QLVLAGPTDAVKQLVQALADKGIRAIALPVSGAFHTPLVGHAHAPFAKAIDKESFSDAHA 832
QLV+AG T A +Q +A+ + G +AIALPVSGAFHTPLV HA PF++AIDK F+
Sbjct: 782 QLVIAGATTATQQAAKAIGELGFKAIALPVSGAFHTPLVAHAQKPFSEAIDKAQFNTPKI 841
Query: 833 VLYANASGDKRPTDGKSLKQSLKAQMLEQVQFESQIESLYRDGVRVFIEFGPKNTLSRLV 892
LYAN +G+ PTD ++K + K ML+ V F Q+E++Y G RVF+EFGPKN L +L
Sbjct: 842 ALYANGTGELHPTDANAIKAAFKDHMLQSVHFSKQLEAMYAAGARVFVEFGPKNILQKLA 901
Query: 893 DAILGERAKACLILSLDAQAVGSQGRADSKLKLAAVELATAGFAITNPDPYREQLSHKAM 952
+ L + ++S++ + +DS+L+ AAV+LA AG + DPY+ +L A
Sbjct: 902 ENTLAAQLNELCLISINP---NPKADSDSQLRSAAVQLAVAGVKLGEIDPYQAELIAPAT 958
Query: 953 PKSPLTVKLSASNYLSPATAARMQASLKDGQISKQTQIVEKIVEKT------------QY 1000
P S + +KL+A+NY+SPAT +M SL+ G+I+ + Q V++IVEK +
Sbjct: 959 P-SAMNIKLNATNYISPATRNKMVDSLQSGKITSRVQYVDRIVEKVVEKVVEKPVIVEKI 1017
Query: 1001 VPKAAPAQPAPAVQTTAASEQTSPAPTAGAGTNVGTGTLEALFAAQQQLAALHQQFLTIP 1060
+ K + A + +QT P + L A FAAQ Q A LHQQFL IP
Sbjct: 1018 LEKVVEVEKPVAQNSNTIQQQTPAQPASFTAGQANQDALSAFFAAQTQAAQLHQQFLAIP 1077
Query: 1061 AQYGEGVQALMQKQLELASAGLPVPAATERALELFHQHQADTLKIHSDFMRAQVLGSEQM 1120
QYG+ V ALM +Q ++AS G+ +P + +R++ELFHQHQA TLK H++FM+ Q S+
Sbjct: 1078 QQYGDTVSALMAEQAKMASLGIAIPESLQRSMELFHQHQAQTLKSHAEFMQLQTSSSQAA 1137
Query: 1121 LSALSGQTLVS--QAPQTAAAVVAAPVAAASQVMAAPVVKA----PEAPVTAPVAAQVAA 1174
L AL GQ QAP AA VA VA APVV+A P+A V +V
Sbjct: 1138 L-ALLGQKPAPQVQAPIQTAAPVAVAVATPVAPAQAPVVQALAAEPKATVVPVSEPKVQQ 1196
Query: 1175 PMPAPAMVIPAAASVAAL-----------PIQDIMLQVVAAKTGYPTEMLDLSMDMEADL 1223
P + P +VAA I+ M+ VVA KTGYP EML+L MDMEADL
Sbjct: 1197 PQVTQQVAQPQVQTVAAATRALSEKPVVQQIETAMMAVVADKTGYPVEMLELGMDMEADL 1256
Query: 1224 GIDSIKRVEILGTVQDELPTLPELDAATLAECRTLEDIVAYMHKVAGTSPVTAATSHSQA 1283
GIDSIKRVEILGTVQDELP LPEL LAECRTL +IVA + PVTA T+ Q+
Sbjct: 1257 GIDSIKRVEILGTVQDELPNLPELSPEDLAECRTLGEIVALFSQAL---PVTAVTASPQS 1313
Query: 1284 V-PTPVSASA-----DITAVMLKVVADKTGYPTEMLDLAMDMEADLGIDSIKRVEILGTV 1337
+ + V+ASA +I M+ VVADKTGYP EML+L+MDMEADLGIDSIKRVEILGTV
Sbjct: 1314 ITQSAVAASAAVSNDEIERTMMAVVADKTGYPVEMLELSMDMEADLGIDSIKRVEILGTV 1373
Query: 1338 QDELPMLPELDAATLAECRTLEDIVAYMHSMTG-AAVSQAPVSQTAAPASHQAAHSSSDI 1396
QDELP LPEL LAECRTL +IVA T A++ +P S T + AA S+ +I
Sbjct: 1374 QDELPKLPELSPEDLAECRTLGEIVALFSQATPVTAITASPQSITQTAVATNAAVSNDEI 1433
Query: 1397 TPVMLKVVADKTGYPAEMLDLAMDMEADLGIDSIKRVEILGTVQDELPTLPELDAATLAE 1456
M+ VVADKTGYP EML+L+MDMEADLGIDSIKRVEILGTVQDELP LPEL LAE
Sbjct: 1434 ERTMMAVVADKTGYPVEMLELSMDMEADLGIDSIKRVEILGTVQDELPKLPELSPEDLAE 1493
Query: 1457 CRTLADIVAYMHSMT----GAAVSQAAVSQVAAQGATQSTQNSSD-ITAVMLNVVADKTG 1511
CRTL +IVA T VS A + + A S S+D I M+ VVADKTG
Sbjct: 1494 CRTLGEIVALFSQATPVTAATTVSHATQNALLASAVAASAAVSNDAIERTMMAVVADKTG 1553
Query: 1512 YPAEMLELAMDMEADLGIDSIKRVEILGTVQDALPGLPEIDPSTLAECRTLGDIIACYGT 1571
YP EMLEL MDMEADLGIDSIKRVEILGTVQD LP LPE+ P LAECRTLG+I+A +
Sbjct: 1554 YPVEMLELGMDMEADLGIDSIKRVEILGTVQDELPKLPELSPEDLAECRTLGEIVALF-- 1611
Query: 1572 DGAQDATDNGKAEAQQTEADADTGIEVEVDIAVSALAAAQDIVASESATASAFESDNATA 1631
+Q T A A S A Q VAS +A ++
Sbjct: 1612 -------------SQATPVTA----------AASVSYATQSAVASSAAVSN--------- 1639
Query: 1632 AAAAATLPTPTPQQVLDTMLTVVAEKTGYPVEMLDLAMDMEADLGIDSIKRVEILGTVQE 1691
++ TM+ VVA+KTGYPVEML+L+MDMEADLGIDSIKRVEILGTVQ+
Sbjct: 1640 ------------DEIERTMMAVVADKTGYPVEMLELSMDMEADLGIDSIKRVEILGTVQD 1687
Query: 1692 RLPGLAEVDAATLAECRTLGQIV--------------ESFSLPNQYVGTDASTDT-ELAP 1736
+LP + E+ LAECRTLG+IV ++ + P Q + DT +L P
Sbjct: 1688 QLPNMPELSPEDLAECRTLGEIVALYAGSQSSSESQQQNHAAPIQEAIAETVEDTIDLPP 1747
Query: 1737 HTGVALKKLQAADRLEAPSATG--LFAAKGRVIILDDGHNAGVLAGRLDAKGHAVTVIRC 1794
H+ V LKKL AA L AT A V+I DDGHNAGV+A +L A+G V V+R
Sbjct: 1748 HSEVMLKKLPAAAELARIIATSDVQLTANSYVVIGDDGHNAGVIAEKLHAQGVKVAVVRS 1807
Query: 1795 DS--LGHQSVLDASIDARTLSQGGDMD-TEIQSLIKALEPVSAFIHLQP--VMAADDGAA 1849
+ S LD+ I + TL D E+ + I+AL ++ FIHLQP AD GA
Sbjct: 1808 PKTVVTSASPLDSHIASFTLEAIDDESICEVINQIEALGQIAGFIHLQPQHKSVADKGAG 1867
Query: 1850 DVKATARFSDEAFSQVSLAFLFAKHLAADFAAEGAHRRAFITAARMDGKLGLSGAD---- 1905
V A DEA + V AFLFAKHL E H R F+T +R+DG G G D
Sbjct: 1868 LVLA-----DEAKASVEQAFLFAKHL-QPLLTERDHCR-FVTVSRIDGGFGYIGMDESAG 1920
Query: 1906 -----VELNQAALFGLTKTLAQEWPHTHCRALDVAAQLDATSLADAVIDALYGADDLLEW 1960
ELNQAAL GLTKTL EWP CRALD+A LDA ++A+AV+ Y D +E
Sbjct: 1921 ALISQSELNQAALSGLTKTLNHEWPGVVCRALDIAPNLDAKTVANAVVQEYYLQDAPVEV 1980
Query: 1961 GIAAD-GRFAALATDAQQISAKTALNSTDKILVTGGAKGVTLDCALALAARTHAHFILAG 2019
GI ++ R +A +A + +L+S DKILVTGGAKGVT +CAL+LA R AHFILAG
Sbjct: 1981 GIDSELERATLVAGNAVLRRSGASLSSADKILVTGGAKGVTFECALSLAKRCKAHFILAG 2040
Query: 2020 RSKALSLNEFPVWAKGVAATELKQAAIQELLAGGKRPTPKEVDALIAPLASALEIQQALQ 2079
RS ++ P WA+G ELK AAI L + G +PTPK+VDAL+ P+ S+LEI ALQ
Sbjct: 2041 RSAHQAI---PAWAQGKNRNELKAAAIAHLQSLGDKPTPKQVDALVWPVQSSLEISHALQ 2097
Query: 2080 AFSDLGASAEYLSMDVSSAESIAKALGPIQAIAPVTGLIHGAGVLADKFIQDKTLDELKR 2139
AF +GASAEYLS+DV+ +IA + PI A++P+TG+IHGAGVLADK IQDKTL EL+R
Sbjct: 2098 AFEAVGASAEYLSLDVNDPAAIASTIAPISALSPITGIIHGAGVLADKHIQDKTLSELER 2157
Query: 2140 VAGTKVDGLKGLLANLD--GLKLVALFSSAAGFYGNKGQSDYAMANEILNKAAHRLAHAK 2197
V GTKV GL LL+ LD L L+ALFSSAAGFYGN GQSDYAM+N+ILNKAA +LA
Sbjct: 2158 VYGTKVTGLNNLLSALDLSQLTLIALFSSAAGFYGNTGQSDYAMSNDILNKAALQLAQQL 2217
Query: 2198 PDCRVVAFDWGPWDGGMVTDSLKKMFQERGVYVIPRPLGAALFAEAVLGRAESQILVGSS 2257
P +V++FDWGPWDGGMV +LKKMF +RGVYVIP GA LFA +L +Q+LVG+
Sbjct: 2218 PQAKVMSFDWGPWDGGMVNPALKKMFIDRGVYVIPLKAGAELFASQLLSDTGAQLLVGTD 2277
Query: 2258 MQGNADQA--GANLKKPEGH---------------SGITLGRTLYRPHLALLEDHQIGGN 2300
MQGN A A+ KKPE I + R+L ++ +EDH I G+
Sbjct: 2278 MQGNTANAVEAASAKKPEADLTTALDPQPMAQTVPQSIRVMRSLDPKRMSFIEDHCINGH 2337
Query: 2301 AVLPTVCALEWMQDAATRHFGGQWQPHDYRLLKGVVFD----SDEKALTMQLNVT---DA 2353
AVLPTVCA++WM++AA H G DYRLLKG++FD + + + ++L +T DA
Sbjct: 2338 AVLPTVCAIDWMREAAKAHLGKAVSVSDYRLLKGIIFDEALLARDAPIELELMLTPLADA 2397
Query: 2354 ------GLSALISCDGRPQYEARL------QPPSPLSLPSEAMAADIRQSADKAVVTGKQ 2401
L+ALIS +GRPQY+A L P + E + + A+ +
Sbjct: 2398 TQQSTEALAALISFEGRPQYQAVLVAQTDDMPDAQRFEVGELHSLMEEITQQPAIANRES 2457
Query: 2402 LYQDGALFHGPALQMIGDVSWFDDGGLGCTVMLPAASVEP-GQAA---------IIQQDA 2451
LY DG LFHGP LQ I +V FDD L V LPA +++ G+ A +D
Sbjct: 2458 LYSDGTLFHGPRLQGISEVLAFDDQQLIAKVALPALALDDCGEFAPDLEDKGTQPFAEDL 2517
Query: 2452 LLQALLVWARLKYDAASLPASLTRAVQHLELSPGEQGQLRLWVKSHSSRQLCADVALYNA 2511
LLQA+LVWARLKY AASLP+++ V + L GE+ L L V HSSR L A++ALY+
Sbjct: 2518 LLQAMLVWARLKYQAASLPSAIGEFVSYSPLGFGEKAVLVLDVIKHSSRTLEANIALYHQ 2577
Query: 2512 QGQLASAMEGVKVTISKSLNQAFLSAKGQE 2541
G+L+ M+ KVT+SK+LNQAFL+ K Q+
Sbjct: 2578 DGRLSCEMKRAKVTVSKTLNQAFLANKPQQ 2607