Pairwise Alignments

Query, 599 a.a., thiamine biosynthesis protein ThiC from Phaeobacter inhibens DSM 17395

Subject, 645 a.a., phosphomethylpyrimidine synthase from Vibrio cholerae E7946 ATCC 55056

 Score =  803 bits (2075), Expect = 0.0
 Identities = 414/624 (66%), Positives = 474/624 (75%), Gaps = 54/624 (8%)

Query: 14  PASRKIYVSGEVHPDIRVPMREISTHPTA-----------GEAPLPVYDSSGPYTDPDVL 62
           P S+K Y+ G   PDIRVP+REI+   T               P+ VYD+SG YTDP   
Sbjct: 24  PNSQKSYLLGS-RPDIRVPVREITLSDTLVGGSKDAPIFEPNEPICVYDTSGVYTDPSHD 82

Query: 63  TDIRQGLPQLRRQWIEARGDVESYQGRDVKPEDNGFVEDDRLTPE------FPVKPAPLR 116
            D+ +GLP+LR +WIE R D        + P  +     +RL  E      +   P   R
Sbjct: 83  IDLYKGLPKLREEWIEERRDTH------ILPSMSSHFARERLADETLDELRYGHLPRIRR 136

Query: 117 GKDGTAPTQLAYARAGIITPEMEYVAIRENQLRELSPCHRD--------GNDFGANIPDY 168
                  TQL YAR GIITPEME+VAIREN  R     H+D        G +FGA++PD 
Sbjct: 137 AMGQHRVTQLHYARQGIITPEMEFVAIRENSRRL---AHQDPSLLQQHAGQNFGAHLPDL 193

Query: 169 VTPEFVRDEIAAGRAIIPANINHPEIEPMIIGRNFLVKINANMGTSAVTSSMEEEVDKLV 228
           +TPEFVR EIA GRAIIP NINHPE EPMIIGRNFLVK+NAN+G S+V+SS+EEEV+KLV
Sbjct: 194 ITPEFVRREIAEGRAIIPCNINHPESEPMIIGRNFLVKVNANIGNSSVSSSIEEEVEKLV 253

Query: 229 WAIRWGADTVMDLSTGRNIHNTREWIVRNSPVPIGTVPIYQALEKVNGIAEDLTWEVFRD 288
           WA RWGADTVMDLSTGRNIH TREWI+RNSPVPIGTVP+YQALEKVNG+AE+LTWEV RD
Sbjct: 254 WATRWGADTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGVAENLTWEVMRD 313

Query: 289 TLIEQAEQGVDYFTIHAGVRLHMVPMTVERVTGIVSRGGSIMAKWCLHHHKESFLYEHFE 348
           TL+EQAEQGVDYFTIHAG+ L  VPMT +RVTGIVSRGGSI+AKWCL HH+E+FLY HF 
Sbjct: 314 TLLEQAEQGVDYFTIHAGLLLRYVPMTAKRVTGIVSRGGSIIAKWCLSHHQENFLYTHFR 373

Query: 349 DICDICRQYDVSFSLGDGLRPGSIADANDEAQFAELETLGELTKIAWAKDCQVMIEGPGH 408
           +IC+IC QYDV+ SLGDGLRPGSIADANDEAQFAEL TLGELT+IAW  D QVMIEGPGH
Sbjct: 374 EICEICAQYDVALSLGDGLRPGSIADANDEAQFAELRTLGELTQIAWEYDVQVMIEGPGH 433

Query: 409 VAMHKIKENMDKQLECCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVT 468
           V MH IK NMD+QL+ CHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVT
Sbjct: 434 VPMHLIKANMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVT 493

Query: 469 PKEHLGLPDRDDVKTGVITYKIAAHAADLAKGLPGAQRRDDALSRARFEFRWEDQFNLSL 528
           PKEHLGLP+++DVKTG+ITYK+AAHAADLAKG PGAQ RD+ALS+ARFEFRWEDQFNL+L
Sbjct: 494 PKEHLGLPNKEDVKTGLITYKLAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLAL 553

Query: 529 DPDTAREFHDQTLPKQAHKVAHFCSMCGPKFCSMRISHDIRAEAQKEGME---------- 578
           DP TAR FHD+TLP+++ KVAHFCSMCGPKFCSM+IS ++R  A  + ++          
Sbjct: 554 DPVTARAFHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYANNQTLDTTVIDLVMPA 613

Query: 579 -----AMAAKFRE----GGELYVP 593
                AM  K RE    G ELY P
Sbjct: 614 ESIQLAMQDKSREFLASGAELYHP 637