Pairwise Alignments
Query, 1010 a.a., diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) (RefSeq) from Shewanella loihica PV-4
Subject, 1183 a.a., EAL domain-containing protein from Ralstonia sp. UNC404CL21Col
Score = 424 bits (1089), Expect = e-122
Identities = 250/760 (32%), Positives = 406/760 (53%), Gaps = 21/760 (2%)
Query: 248 TWTELTYFEDLKADMTQFQRMLKGEIDAYEMDKRFVAKDGEIVYTHLTVACRRNHN-MVD 306
T+ + + +D+ A + +L + D+++ R + + + + R+ +
Sbjct: 423 TFHQFVHPDDVDAFAQDLRAVLNSDRDSWQHVCRVIDANRATRTVEIRASLYRDQDGRAV 482
Query: 307 MVIAGLIDITEHKRADMAMRTSQERLALVLESSDLGMWDWDIKSNETKRNPWCAKVLGCD 366
++ G+ DI++ + +R+S+ L++ + + LG W WD+ + T + + G
Sbjct: 483 RMVGGVTDISQRSAIEQELRSSEANLSVAEQIALLGSWRWDVLRDSTTWSSGMYVLTGMP 542
Query: 367 L---ERLNRDSRIWIDAIHPQDRMAVLNSIDRHLKGETQKHYIEYRLISLSGEEHWILDT 423
+ ++ + + + R A ++ E + + +E +I GE W+L
Sbjct: 543 PGAPPAFAQQAQFFTADSYNRLRDAASRAVT-----EGEPYSLELEMIRRDGEHRWVLSR 597
Query: 424 GKVVSRDRNGLPTRMCGVHSDITEQKKVQESLELAASVYNNSSEAMSVQDHKGH---IIT 480
G + +R+ + + G DITE+++ E L L V + ++V D + I+
Sbjct: 598 GNIERNERDEV-IALFGTMQDITERRESDEQLRLLRRVVESVPSGITVADAQEPDLPIVY 656
Query: 481 INAAFTAITGYSQEEALTQNIRILQSSRTPRSQYDEMNSAIRDTGYWQGELWIKNKSGEE 540
+N F +TGY EE L +N R L SS + +E+ +A+RD + L K G
Sbjct: 657 VNPGFERMTGYRAEEVLGRNARFLHSSEPGQPALNEVRTALRDESEIRVLLRNFRKDGHA 716
Query: 541 YMVWLTINTIFDQHGQVYRRVALFSDITEKKEAEHIIWKQANYDPLTGLPNRRMLLEYLN 600
++ ++ + D G V V + D+TE++ + + A DPLTGLPNR +L + +
Sbjct: 717 FLNNFLLSPVRDAKGAVTHYVGIQDDVTEQEMTRTRLAQHATIDPLTGLPNRTLLADRVQ 776
Query: 601 TEILRIDRNHSHFALMFLDLDFFKEVNDTLGHDMGDLLLQETAKRLKGCIRESDVVARLG 660
+ R S F + +++D FK VND+LGH +GD +L+ A+RL+ D VAR G
Sbjct: 777 QSVEMAARQRSRFYVALVNIDRFKVVNDSLGHLLGDEVLRRVAERLRDAADTVDTVARFG 836
Query: 661 GDEFTVVLSGIDSPSGVERVAQSILERIAEPYSLGDETAYISASIGITIYPDDATSIEGL 720
GD F +V+S S R + AEP + +++ASIG+ YP + L
Sbjct: 837 GDVFALVISHAGS-----RGVDFGFDLFAEPVRVEGHEVFVTASIGVAEYPAHGADADSL 891
Query: 721 LKHADQAMYAAKEQGRNRFHYFTPSMQEYARYRMALIKDLRNAINRKEFELFYQPIVDMN 780
++HA+ AMY AK+ GRNR +F P M YR+ L +R A+ + +F L YQP +D
Sbjct: 892 IRHAEMAMYYAKQNGRNRLEFFAPEMDIGVSYRLNLEHQIRAALEQGQFRLLYQPQIDTK 951
Query: 781 KLGVYKAEALIRWVHPQRGLVSPGEFIPVAEETGLINEIGNWVFEKAAQQSARWRTQH-G 839
V EALIRW+HP RGL+ P FIPVAEE+GLI EIGNWV +AAQQ A W +
Sbjct: 952 TGRVCGLEALIRWIHPTRGLLPPAAFIPVAEESGLIVEIGNWVLTEAAQQRAEWHKRGLA 1011
Query: 840 VEIQISINKSPIQFRDEGDTFSDWLALLRHLELSSNAICVEITEGLLLDASMGVTDKLLA 899
++ +++N SP+QF+ G L L R L S + +E+TE +L++ + + L A
Sbjct: 1012 DDLTLAVNVSPLQFK-RGTVLPTLLKLQRQYGLGSGFLELEVTESMLMEGTERTIEDLTA 1070
Query: 900 YRDAGIQVSLDDFGTGYSSLAYLKKFDIDYLKIDQSFTRNLESDSDGVALCEAIIVMAHK 959
R G+++++DDFGTGYSSLAYLK+ ID +KID++F ++++ DS+ A+C ++V+AH
Sbjct: 1071 IRQLGVRIAIDDFGTGYSSLAYLKRLPIDLIKIDRAFVKDIDRDSNDAAICTTVVVLAHN 1130
Query: 960 LGIKVIAEGVETQFQHDILASAGCDFAQGYLYSKPVSLPE 999
LG+KV AEGVE Q LAS CD QGY +S+P+ LPE
Sbjct: 1131 LGVKVCAEGVEDAAQSAFLASHQCDVLQGYYFSEPL-LPE 1169
Score = 41.6 bits (96), Expect = 3e-07
Identities = 51/272 (18%), Positives = 109/272 (40%), Gaps = 18/272 (6%)
Query: 319 KRADMAMRTSQERLALVLESSDLGMWDWDIKSNETKRNPWCAKVLGCDLERLNRD----- 373
+R D + ER V +++ ++DWDI + E+ N ++LG D D
Sbjct: 356 QRHDATVHRLTERFQRVARATNDWIFDWDIATGESWANASLHRLLGSDALLGQGDDDGTG 415
Query: 374 -----SRIWIDAIHPQDRMAVLNSIDRHLKGETQKHYIEYRLISLSGEEHWILDTGKVVS 428
+ + +HP D A + L + R+I + + + +
Sbjct: 416 GGTSRTLTFHQFVHPDDVDAFAQDLRAVLNSDRDSWQHVCRVIDANRATRTV-EIRASLY 474
Query: 429 RDRNGLPTRMCGVHSDITEQKKVQESLELAASVYNNSSEAMSVQDHKGHII----TINAA 484
RD++G RM G +DI+++ +++ L + + + + + + + ++ T ++
Sbjct: 475 RDQDGRAVRMVGGVTDISQRSAIEQELRSSEANLSVAEQIALLGSWRWDVLRDSTTWSSG 534
Query: 485 FTAITGY--SQEEALTQNIRILQSSRTPRSQYDEMNSAIRDTGYWQGELWIKNKSGEEYM 542
+TG A Q + + R + D + A+ + + EL + + GE
Sbjct: 535 MYVLTGMPPGAPPAFAQQAQFFTADSYNRLR-DAASRAVTEGEPYSLELEMIRRDGEHRW 593
Query: 543 VWLTINTIFDQHGQVYRRVALFSDITEKKEAE 574
V N ++ +V DITE++E++
Sbjct: 594 VLSRGNIERNERDEVIALFGTMQDITERRESD 625