Pairwise Alignments

Query, 404 a.a., Membrane bound metalloprotease from Mycobacterium tuberculosis H37Rv

Subject, 452 a.a., zinc metalloprotease from Vibrio cholerae E7946 ATCC 55056

 Score = 89.4 bits (220), Expect = 2e-22
 Identities = 48/131 (36%), Positives = 77/131 (58%), Gaps = 7/131 (5%)

Query: 8   VLFALAILISVALHECGHMWVARRTGMKVRRYFVGFGPTLWS-TRRGETEYGVKAVPLGG 66
           + F +A+ I VA+HE GH WVARR G+KV ++ +GFG ++W       TEY +  +PLGG
Sbjct: 9   IAFIIALGILVAVHEFGHFWVARRCGVKVEKFSIGFGKSIWKRVGHDGTEYSISMIPLGG 68

Query: 67  FCDIAGMTPVEELDPDERDRAMYKQATWKRVAVLFAGPGMNLAICLVLIYAIALVWGLPN 126
           +  +     V+++  +++  A  KQ+ WKR A++ AGP  N  +  +  Y +  + G+P 
Sbjct: 69  YVKMLD-GRVDDVPAEQQAMAFDKQSLWKRSAIVSAGPIFNF-LFAIFAYWLVFMIGVPA 126

Query: 127 LHPPTRAVIGE 137
           + P    VIGE
Sbjct: 127 VKP----VIGE 133



 Score = 60.1 bits (144), Expect = 1e-13
 Identities = 68/246 (27%), Positives = 112/246 (45%), Gaps = 50/246 (20%)

Query: 126 NLHPPTRAVIGETGC--VAQEVSQGKLEQCTGPGPAALAGIRSGDVVVKVGDTPVSSFDE 183
           N  P T + +G  G      E+S  +L   +  G    AG++ GD V+++    V ++ +
Sbjct: 202 NFDPETESAMGALGFKPFTPEISN-QLTNVSAQGAGERAGLQVGDTVLQINGQAVEAWQQ 260

Query: 184 MAAAVRKSHGSVPI--VVERDGTAIVTYVDIESTQRWIPNGQGGELQPATVGAIGVGAAR 241
           +  A++ SH + PI  +VER G  +   +        IP+ +  EL    V    +G A 
Sbjct: 261 VVNAIQ-SHPNAPIAVMVERAGQQVELTL--------IPDSR--ELSQGKV----IGFAG 305

Query: 242 VGP------------VRYGVFSAMPATFAVTG---DLTVEVGKALAALPTKVGALVRAIG 286
           + P            +++GVF ++      +G   DLTV + K L      VG +     
Sbjct: 306 IAPKVAEWPQNYRFELQFGVFESLGKAVEKSGQVIDLTVSMLKKLL-----VGDV----- 355

Query: 287 GGQRDPQTPISVVGASIIGGDTVDHGLWVAFWFFLAQLNLILAAINLLPLLPFDGGHIAV 346
            G  +   PIS+   +   G T D+G +V F  FLA +++ L  INL+PL   DGGH+  
Sbjct: 356 -GLNNLSGPISIAKGA---GTTADYG-FVYFLGFLALISINLGIINLVPLPMLDGGHLLF 410

Query: 347 AVFERI 352
            + E +
Sbjct: 411 FMIEAV 416