Pairwise Alignments
Query, 1194 a.a., Probable transmembrane multidrug efflux pump from Mycobacterium tuberculosis H37Rv
Subject, 601 a.a., lipid transporter ATP-binding/permease from Pseudomonas fluorescens FW300-N2C3
Score = 257 bits (656), Expect = 2e-72
Identities = 190/582 (32%), Positives = 296/582 (50%), Gaps = 32/582 (5%)
Query: 6 WWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPL---VTKRVID-----DAIAADHRPL- 56
++RL GYV + LL L + A P+ + K +D DA+ + P
Sbjct: 17 YFRLLGYVKPYAGIFLLSI---LGFVIFASTQPMLAGILKYFVDGLSNPDAVLFPNVPYL 73
Query: 57 --------APWAVVLVAAAGATYLLMYVRRYYGGRIAHLVQHDLRMDAFQALLRWDGRQQ 108
P ++L+AA L ++ YY R++ + HDLR++ F+ LL R
Sbjct: 74 KDLKLLMAVPLLIILIAAWQG--LGSFLGNYYLARVSLGLVHDLRVELFKKLLVLPNRYF 131
Query: 109 DRWSSGQLIVRTTNDLQLVQALLFD-VPNVLRHVLTLLLGVAVMTWLSVPLALLAVLLVP 167
D +SG LI R T ++ +V D + V+R LT++ A + W++ L L+ + ++P
Sbjct: 132 DTHNSGHLISRITFNVTMVTGAATDAIKVVIREGLTVVFLFAYLVWMNWKLTLVMLAILP 191
Query: 168 VIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDAAVCGIRVVKAFGQEERETVKLVTASRA 227
+I ++ + + + Q VT V + G RVV++FG E E + +AS+
Sbjct: 192 LIAVMVSSTSKKFRKQSKKIQVAMGDVTHVASETIQGYRVVRSFGGEAYEEQRFTSASQG 251
Query: 228 LYAAQLRVARLNAHFGPLLQTLPALGQMAVFALGGWMAAQGSITVGTFVAFWACLTLLAR 287
QLR+ R A + P+LQ + A+ L ++ +G T G VA+ LL +
Sbjct: 252 NTDKQLRMTRTGAVYTPMLQLVIYTAMAALMFLVLFL--RGDATAGDLVAYITAAGLLPK 309
Query: 288 PACDLAGMLTIAQQARAGAVRVLELIDSRPTLVDGTKPLSPEARLS--LEFQRVSFGYV- 344
P L+ + + Q+ AGA + E +D P + GT + R+S L+ + +SF Y
Sbjct: 310 PIRQLSEVSSTIQKGVAGAESIFEQLDVEPEVDGGTVE---QERVSGRLDVRNLSFTYPG 366
Query: 345 ADRPVLREISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRELTLD 404
ADR VL++IS S G+ +A+VG GSGKSTLASL R Y G + + ++ + L
Sbjct: 367 ADREVLKDISFSAAPGQMIALVGRSGSGKSTLASLIPRFYHHEVGQILLDDVEIEDYRLR 426
Query: 405 SLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPE-QIATAARAAHIEEFVNTLPDGYQTA 463
+LR + V + LF+ T+ NIAYG P I AAR A+ +F+ LP+G T
Sbjct: 427 NLRRHVAQVTQHVTLFNDTVANNIAYGDLAGAPRADIEKAARDAYAMDFIEQLPNGLDTE 486
Query: 464 VGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSAVDAVIECGIQEVLREAIADRTAV 523
VG G+ LSGGQRQR+A+ARALL LLI+D+ TSA+D E IQ L + + RT +
Sbjct: 487 VGENGVLLSGGQRQRLAIARALLKNAPLLILDEATSALDTESERHIQAALDQVMKGRTTL 546
Query: 524 IFTRRRSMLTLADRVAVLDSGRLLDVGTPDEVWERCPRYREL 565
+ R S + AD + V+D GR+++ GT E+ + Y L
Sbjct: 547 VIAHRLSTIEKADLILVMDQGRIVERGTHGELLAQNGYYARL 588
Score = 193 bits (490), Expect = 4e-53
Identities = 138/464 (29%), Positives = 224/464 (48%), Gaps = 7/464 (1%)
Query: 716 FEDDGDAQIVTAVTADVEAIVAFLRTGLVVAVISVVTLVGILVALLAIRARLVLLIFTTM 775
F+ +++ +T +V + + V + +T+V + L+ + +L L++ +
Sbjct: 131 FDTHNSGHLISRITFNVTMVTGAATDAIKVVIREGLTVVFLFAYLVWMNWKLTLVMLAIL 190
Query: 776 PVLALATWQFRRASNWTYRRARHRLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSD 835
P++A+ + ++ + +G VT E G R+ ++F E Q + + S
Sbjct: 191 PLIAVMVSSTSKKFRKQSKKIQVAMGDVTHVASETIQGYRVVRSFGGEAYEEQRFTSASQ 250
Query: 836 DYRRLGVRGQRLLALYYPFVALLC--SLATTLVLLDGAREVRAGVISVGALVTYLLYIEL 893
+R R A+Y P + L+ ++A + L+ R G + G LV Y+ L
Sbjct: 251 GNTDKQLRMTRTGAVYTPMLQLVIYTAMAALMFLVLFLR----GDATAGDLVAYITAAGL 306
Query: 894 LYTPIGELAQMFDDYQRAAVAAGRIRSLLSTRTPSSPAARPVGTLRGEVVFDAVHYSYRT 953
L PI +L+++ Q+ A I L + G + + ++Y
Sbjct: 307 LPKPIRQLSEVSSTIQKGVAGAESIFEQLDVEPEVDGGTVEQERVSGRLDVRNLSFTYPG 366
Query: 954 REVPALAGINLRIPAGQTVVFVGSTGSGKSTLIKLVARFYDPTHGTVRVDGCDLREFDVD 1013
+ L I+ GQ + VG +GSGKSTL L+ RFY G + +D ++ ++ +
Sbjct: 367 ADREVLKDISFSAAPGQMIALVGRSGSGKSTLASLIPRFYHHEVGQILLDDVEIEDYRLR 426
Query: 1014 GYRNRLGIVTQEQYVFAGTVRDAIAYGR-PDATDAQVERAAREVGAHPMITALDNGYLHQ 1072
R + VTQ +F TV + IAYG A A +E+AAR+ A I L NG +
Sbjct: 427 NLRRHVAQVTQHVTLFNDTVANNIAYGDLAGAPRADIEKAARDAYAMDFIEQLPNGLDTE 486
Query: 1073 VTAGGRNLSAGQLQLLALARARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTL 1132
V G LS GQ Q LA+ARA L + +L+LDEAT ALD +E +Q A + RTTL
Sbjct: 487 VGENGVLLSGGQRQRLAIARALLKNAPLLILDEATSALDTESERHIQAALDQVMKGRTTL 546
Query: 1133 IVAHGLAIAEHADRIVVLEHGTVVEDGAHTELLAAGGHYSRLWA 1176
++AH L+ E AD I+V++ G +VE G H ELLA G+Y+RL A
Sbjct: 547 VIAHRLSTIEKADLILVMDQGRIVERGTHGELLAQNGYYARLHA 590