Pairwise Alignments

Query, 812 a.a., DNA gyrase, A subunit (RefSeq) from Desulfovibrio vulgaris Miyazaki F

Subject, 894 a.a., DNA topoisomerase (ATP-hydrolyzing) subunit A from Vibrio cholerae E7946 ATCC 55056

 Score =  807 bits (2085), Expect = 0.0
 Identities = 421/870 (48%), Positives = 582/870 (66%), Gaps = 66/870 (7%)

Query: 5   VSIEKELRKSYLEYSLSVIIGRAIPDARDGLKPVHRRIMFAQHELGNGYTRPPKKSARVV 64
           V+IE ELR SYL+Y++SVI+GRA+PD RDGLKPVHRR++FA + LGN + +  KKSARVV
Sbjct: 11  VNIEDELRSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKAYKKSARVV 70

Query: 65  GDVIGKYHPHGDSAVYDALVRMAQDFSMRDPLVDGQGNFGSIDGDAAAAMRYTEVRMSRL 124
           GDVIGKYHPHGDSAVYD +VRMAQ FS+R  LVDGQGNFGSIDGD+AAAMRYTEVRMS++
Sbjct: 71  GDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEVRMSKI 130

Query: 125 AGEFLADIDKETVDFRPNYDNTLLEPSVLPTKVPNLLLNGSSGIAVGMATNIPPHNLGEL 184
           A E LAD+DKETVD+ PNYD T   P+VLPTK+PNLL+NG+SGIAVGMATNIPPHNLGE+
Sbjct: 131 AHELLADLDKETVDYVPNYDGTEQIPAVLPTKIPNLLINGASGIAVGMATNIPPHNLGEV 190

Query: 185 CGALLHIVDEPGCTVEDLMDHVKGPDFPTAGFVYAGQGLYDAYTTGRGTVKVRGKVEIEE 244
               L  +D    T+++LMD++ GPDFPTA  +   +G+ DAY TGRG V +R K EIE 
Sbjct: 191 IDGCLAYIDNEAITIDELMDYIPGPDFPTAALISGRKGIIDAYKTGRGKVYMRSKAEIET 250

Query: 245 RKKGLQAIVIREIPFALNKSSLVEKIAALVNERKIDGVADLRDESDRKGIRVVIDLKRGT 304
            K G + I++ EIP+ +NK+ L+EKIA LV E+K++G++ LRDESD+ G+R+VI+ KR  
Sbjct: 251 DKNGKETIIVSEIPYQVNKARLIEKIAELVKEKKVEGISALRDESDKDGMRIVIECKRDA 310

Query: 305 IPDIVVNALYKYTPLESSFGINMLAVVGNRPQLLNLKQALEIFLEHRREVIIRRTRYDLR 364
           + ++V+N LY  T L+++FGINM+A+   +P+L NLK+ L+ F++HRREV+ RRT ++LR
Sbjct: 311 VGEVVLNNLYANTQLQTTFGINMVALDNGQPKLFNLKEMLKCFVDHRREVVTRRTIFELR 370

Query: 365 KAEARAHILEGLRIALDNIDEVVALIRASKTPQDAKDALM-------------------- 404
           KA  RAHILEGL +AL NIDE++ LIR + TP +AK+ L+                    
Sbjct: 371 KARERAHILEGLALALANIDEIIELIRRAATPAEAKEGLIARGWDLGNVAAMLERAGTDA 430

Query: 405 --------------GRFTLSEAQAQAILDMRLQRLTNLEHEKLIEEYNELLKKIEFFRSV 450
                         G++ L+E QAQAILD+RL +LT LEHEK+++EY +LL++I     +
Sbjct: 431 ARPEWLEPQYGIRDGKYFLTEQQAQAILDLRLHKLTGLEHEKILDEYKQLLEEIAALMHI 490

Query: 451 LENPEVLRSVIREEIGELRDTFATKRRTEVLEEELDGIDIEDLIPDEDVVITLSRRGYIK 510
           L + E L  VIREE+  +R  F+  RRTE+     D ID+E+LI  EDVV+TLS  GY+K
Sbjct: 491 LASTERLMEVIREELEAIRAGFSDARRTEITAATHD-IDMEELIAREDVVVTLSHEGYVK 549

Query: 511 RTTLDNYQQQRRGGKGIAGVHTSEDDFVQDFLTTTNHQYLLLFTNHGRMHQIKVHRVPEG 570
              L +Y+ QRRGGKG +     E+D+++  L    H  +LLF+  G+ +++KV+++P  
Sbjct: 550 YQLLSDYEAQRRGGKGKSATKMKEEDYIERLLVANTHDNILLFSTRGKTYRMKVYQLPLA 609

Query: 571 SRTAKGVHIANLVQLDKDELVTNVLTVREFAEDRYFLFVTRRGMVKRSSASLYAKCRKTG 630
           SRTA+G  I NL+ L+++E +T +L V EF+ED++    T  G VK++S   +A  R  G
Sbjct: 610 SRTARGKPIVNLLPLEENERITAILPVTEFSEDKFIFMATGDGTVKKTSLDQFANVRANG 669

Query: 631 LIAVGLRPDDELIMVREVDEHCHIVLTTGDGMAIRF------------------------ 666
           LIA+ LR +D LI V   D    I+L +  G  +RF                        
Sbjct: 670 LIALNLRDEDSLIGVDITDGESEIMLFSKFGKVVRFKESEETAVVDENGQPVLDENGQPE 729

Query: 667 -QCEDVRPMGRSATGVKGIALRGKDRVVACVILAEEDTTSMIMSVSANGFGKRTKADLYR 725
            + + VRPMGR+A GV+G+ L   D+VV+ ++     T   +++V+ NG+GKRT    Y 
Sbjct: 730 IKFKGVRPMGRTAAGVRGMKLADGDQVVSLIV---PKTEGDVLTVTENGYGKRTSLSEYP 786

Query: 726 VQSRGGVGVKNFKVTPKTGDVIGAMPVRDDDALVLLTSTNKILRMGLNDVRSVGRATQGV 785
            + RG  GV + KV+ + G V+GA+ V + D  +++T+   ++R  + +V  VGR TQGV
Sbjct: 787 TKGRGTQGVVSIKVSERNGSVVGAVQVAEGDEFMMITNAGTLVRTRVAEVSQVGRNTQGV 846

Query: 786 RLVRLDEGALVVGFDRID---EREVVDGEE 812
            L+R  EG  VVG  RID   E E+ +GEE
Sbjct: 847 TLIRTSEGESVVGLQRIDEIEESELPEGEE 876