Pairwise Alignments

Query, 557 a.a., AMP-binding protein from Methanococcus maripaludis S2

Subject, 648 a.a., acetyl-CoA synthetase (TIGR) from Desulfovibrio vulgaris Hildenborough JW710

 Score =  217 bits (552), Expect = 1e-60
 Identities = 162/555 (29%), Positives = 273/555 (49%), Gaps = 40/555 (7%)

Query: 33  NFAYDIVDEYAKIAPE-KIAIIWCDDNNDEKIFTFKDMKKYSDKAANFFLKHGIKKGDTV 91
           N  ++ +D + + +   ++A+IW  +  D + FT+ D+ +  ++ AN     G+ KGD V
Sbjct: 84  NIVHNALDRHIETSNRHRLALIWEGEPGDSRRFTYFDLYREVNRLANAMRSLGVTKGDRV 143

Query: 92  MLTLKSRYEFWFCMLGLHKIGAVAIPATHMLTTKDIVYRIEKAGLKMIVCIG---ENG-- 146
           ++ +    E  F ML   KIGAV        + + +  R+E A   +++ +     NG  
Sbjct: 144 VIYMPPLPETVFAMLACAKIGAVHSTVFGGFSARSLCDRVEDARPTLLLTVDGFYRNGRV 203

Query: 147 --VPDYVDEAVSEINSD----------VLKACVSNLNNDSWIDFSKELEESSEDFTRPVG 194
             +    D+AV  ++ +          V +A +     D    +  +L       T  + 
Sbjct: 204 VPLKPVADDAVDALSPEARAGLHHVVVVHRAHLETPMRDGRDIWYHDLVRGQS--TEALT 261

Query: 195 EMDTKNDDVLVAYFSSGTTGYPKLIQHDHE-YPLGHITTAKYWQNVEDDGLHYTVADSGW 253
           E+ + ND + V Y +SGTTG PK + H H  Y +G   T ++  +V    + +  A+ GW
Sbjct: 262 EVLSANDPLFVLY-TSGTTGKPKGLVHSHGGYMVGVHRTMRWVFDVRPTDIFWCTAEPGW 320

Query: 254 AKCIRGKLYGQWIAGTAVFVYDYDRF--DAGNMLEKIAKYKITTFCAPPTIYRFMIKQDI 311
                  +YG  +AGT   +Y+      +AG +   + ++ +T     PT+ R +++   
Sbjct: 321 ITGHSYGVYGPLMAGTTTVLYEGHPLYPEAGRLWSMVERWGVTILYTVPTVIRMLMRFGP 380

Query: 312 ---SKADFSSLHYAVTAGEPLNPEVYNKFLEFTG---LRLMEGFGQTET-VVSVANFTWM 364
              ++ D ++L    T GEP++PE +  F    G     +++ + QTET ++ V+     
Sbjct: 381 LYPARHDITTLRLLATVGEPISPETWVWFYRTIGRGRCPVLDTWWQTETGMIMVSPLPVS 440

Query: 365 DPKPGSMGKPVPIFDLMIKGPDGKECDVGEEGELAFKTEDGKPLGLFSGYFKDPERTKKA 424
             KPGS+ +P+P  D+ I   +G     G  G L  K        +  G F D E  ++ 
Sbjct: 441 ALKPGSVARPLPGVDVDIVDGEGAPVPPGRGGLLVVKNPWP---AMACGVFGDDEAFRRL 497

Query: 425 WYD---GYYHTGDTAWKDEDGYLWFVGRNDDLIKSSGYRIGPFEVESALISHPAVLECAI 481
           +++   G+Y TGD A +D+DGY+W  GR DD+I  +G+RIG  E+E+AL SHPAV ECA+
Sbjct: 498 YWERFPGWYCTGDVARRDDDGYIWIQGRADDVILIAGHRIGTAEMEAALASHPAVAECAV 557

Query: 482 TGVPDPVRGQIVKATIVLTSEYEASEE---LKKELQDHVKHNTAPYKYPRAIEFVKELPK 538
            GVPD ++G++ KA +VL    EA+ E   L   L  HV+    P    R + F + LP+
Sbjct: 558 IGVPDRLKGEVGKAFVVLRDTEEAAAEEQALATSLVGHVRRELGPVAVIRDVVFREGLPR 617

Query: 539 TISGKIRRVEIRETD 553
             SGKI R  +R  +
Sbjct: 618 NRSGKIMRRILRSEE 632