Pairwise Alignments

Query, 542 a.a., cation:proton antiporter from Methanococcus maripaludis S2

Subject, 528 a.a., cation:proton antiporter from Vibrio cholerae E7946 ATCC 55056

 Score =  126 bits (317), Expect = 2e-33
 Identities = 117/495 (23%), Positives = 231/495 (46%), Gaps = 33/495 (6%)

Query: 12  LTGILVSPYFLNIVRF--EESISTLGHYGVTILLFMVGISLNPGYF--KEIGKISLITGL 67
           L G L++ + LN   F   +++S L   GVT+LLF +G+ L       KEI   S I  L
Sbjct: 24  LVGFLIAGFALNAYGFTSNDTLSLLADLGVTLLLFTIGLKLEVKTLLAKEIWAGSTIHNL 83

Query: 68  -GQILFTFSIGFLISVFLGYSLIESM------YISIALTFSSTIIIMKLISDKGDIDKLY 120
               LFT  +  LI   LG   +  +       I  AL+FSST+  +K + +KG+++  Y
Sbjct: 84  LSTALFTLLL--LIFKQLGLDSLADLSFDKLILIGFALSFSSTVFAVKSLQEKGEMNATY 141

Query: 121 GKISIGFLIVQDIVAMAILVLISAFNVQSGAGELLFLIISKIVLILTAIYIFTKYALSNF 180
           G ++IG L++QDI A+  L         +G     + I   ++ +L  ++    Y L ++
Sbjct: 142 GTLAIGILVMQDIFAVVFL------TASTGKLPEWYAIGLFVLPLLRPLF----YELLDW 191

Query: 181 ISYASKNQEFLFLFSLMWCFTL-ASLFHLLGFSSEIGALIAGIVLAIFPERYEIASKVRP 239
           + +     E L LF + +   + A  F L+G   ++GALI G++LA   +  E++  +  
Sbjct: 192 VGHG----EMLVLFGIFFALVVGAGSFQLVGMKPDLGALILGMMLASHHKASELSKALFN 247

Query: 240 LRDFFLILFFVVLGVQMTFETSGNFIIPAIILSIFVLFGNPIIVMILMGAFGYTKKTGFL 299
           L++ FL+ FF+ +G+     T+G   I   +L + +L    ++   ++  F +  +T  L
Sbjct: 248 LKELFLVCFFLNIGLSAHPTTTG---IMLALLLLLLLPIKGVLYFWVIHQFHFRVRTSLL 304

Query: 300 AGLTVAQISEFSLIIASLGLRNGHISQEIVSMITLIGIMTIAGSSYFITYSERIYALLSN 359
           A L++   SEF LI+  L  + G I+ +I+  + +   ++   ++        IY   + 
Sbjct: 305 ASLSLFNFSEFGLIVGGLAFKMGWINSDILVALAVSVPLSFILAAPIERKGHAIYQRSAK 364

Query: 360 YLSIFEKKTKISEKDFKNKNTGEIILFGADRTGKNILNVIENSK-ERFLIIDYNPKIIKN 418
           +L     ++  +     +    ++++ G  R G+     + +   E  L ++   +   +
Sbjct: 365 WLKEQAAESLHTRDRLIDPGEAQVLILGMGRIGRGAYEELTSRHGEICLGVEIREEAANS 424

Query: 419 LSKRGYNSVYGDASNLELLNEL-NFKESKMLISTISDIETDILLIKTILKSNKNAIIIVI 477
             + G N + GDA++ +    + +  + K+++  +   + + + ++ + K +    I  I
Sbjct: 425 HREEGRNVISGDATDPDFWERIFDTGKVKLVLLAMPHHQANQIALEQLQKRHYQGQIAAI 484

Query: 478 AHKIEDAIKLYEEGA 492
           A   +    L E GA
Sbjct: 485 AEYPDQIESLLEHGA 499