Pairwise Alignments

Query, 648 a.a., acetyl-CoA synthetase (TIGR) from Desulfovibrio vulgaris Hildenborough JW710

Subject, 636 a.a., acetate--CoA ligase from Methanococcus maripaludis S2

 Score =  580 bits (1494), Expect = e-170
 Identities = 287/622 (46%), Positives = 398/622 (63%), Gaps = 10/622 (1%)

Query: 27  DAVVNPQDVARAREQAGTAPLAFWEEAAEELEWFRRWDGVLDDSNAPFMRWFPGALCNIV 86
           D  +  +  +  +++A   P  FW E A+ LEW + WD  LD  N P+ +WF G   N  
Sbjct: 5   DKYIMLEKYSELQQKALDDPEKFWGEQAKCLEWDKTWDKALD-WNPPYAKWFKGGSLNAS 63

Query: 87  HNALDRHIETSNRHRLALIWEGEPGDSRRFTYFDLYREVNRLANAMRSLGVTKGDRVVIY 146
           +N +DRHI+ + R++ A+I E E G     TY++LYREVN+ AN + +LGV KGD V IY
Sbjct: 64  YNCVDRHIKGNRRNKAAIICEKEDGSCGILTYYELYREVNKFANVLENLGVEKGDVVTIY 123

Query: 147 MPPLPETVFAMLACAKIGAVHSTVFGGFSARSLCDRVEDARPTLLLTVDGFYRNGRVVPL 206
           MP + E + AMLAC++IGA+H+ VF GFS+ +L DR+ D++  +L+T +  YR G+ + L
Sbjct: 124 MPMMTEAIIAMLACSRIGAIHNVVFSGFSSDALADRINDSKSKILVTTNLLYRRGKEIDL 183

Query: 207 KPVADDAVDALSPEARAGLHHVVVVHRAHLETPMRDGRDIWYHDLVRGQSTEALTEVLSA 266
           K + D A+   +      + HVV   R   E  +  G++ ++ +L+ G  +      + +
Sbjct: 184 KKILDKALLNCN-----SIKHVVYAKRGIEEFNLVSGKEYFWDELMGGAKSYVEPVPVES 238

Query: 267 NDPLFVLYTSGTTGKPKGLVHSHGGYMVGVHRTMRWVFDVRPTDIFWCTAEPGWITGHSY 326
             PLF+LYTSGTTG PKG+VHS GGY+    +TM W + +   D+FWCTA+ GWITGH+Y
Sbjct: 239 EHPLFILYTSGTTGSPKGVVHSTGGYLTYATKTMDWTWGLNEMDVFWCTADIGWITGHTY 298

Query: 327 GVYGPLMAGTTTVLYEGHPLYPEAGRLWSMVERWGVTILYTVPTVIRMLMRFGPLYPARH 386
            VYGPL  G T VLYEG   YPE  RLW +VE  GVTILYT PT IRMLM +G  +   H
Sbjct: 299 VVYGPLSLGATIVLYEGAIDYPEPDRLWGIVENHGVTILYTAPTAIRMLMMYGEKWVNTH 358

Query: 387 DITTLRLLATVGEPISPETWVWFYRTIGRGRCPVLDTWWQTET-GMIMVSPLPVSA--LK 443
           D++TLRLL +VGEPI+P  W W+Y+ IG+ +CP+ D +WQTET G I+  P+ + +  LK
Sbjct: 359 DLSTLRLLGSVGEPINPRAWKWYYKVIGKEKCPICDCYWQTETGGHIIYPPIGIQSVPLK 418

Query: 444 PGSVARPLPGVDVDIVDGEGAPVPPGRGGLLVVKNPWPAMACGVFGDDEAFRRLYWERFP 503
           PGS   P  G+DVD+VD EG PV     G L++K PWP M  G++ +DE +R  YW+RF 
Sbjct: 419 PGSATFPGIGIDVDVVDNEGNPVDANVKGNLIIKRPWPGMLAGLWNNDERYRAAYWDRFK 478

Query: 504 GWYCTGDVARRDDDGYIWIQGRADDVILIAGHRIGTAEMEAALASHPAVAECAVIGVPDR 563
             + T D A +D DGYIW+ GR+D+V+ ++GHRIGTAE+E  L S+  VAE AV+G PD 
Sbjct: 479 NKFSTSDYAIKDQDGYIWVLGRSDEVLNVSGHRIGTAELEHELVSNKMVAESAVVGKPDD 538

Query: 564 LKGEVGKAFVVLRDTEEAAAEEQALATSLVGHVRRELGPVAVIRDVVFREGLPRNRSGKI 623
           +KGEV  AFV+L +        +  A  L+ H+R  +GP+     + F   LP+ RSGKI
Sbjct: 539 VKGEVPVAFVILNEKYRELPSNEVKA-ELIKHIRDTVGPIGTPAMIFFVNKLPKTRSGKI 597

Query: 624 MRRILRSEEMGVETGDLSTLED 645
           MRRIL+   MG E GD++TLED
Sbjct: 598 MRRILKKLIMGEEIGDVTTLED 619