Pairwise Alignments

Query, 783 a.a., NAD-dependent DNA ligase from Caulobacter crescentus NA1000

Subject, 678 a.a., NAD-dependent DNA ligase from Marinobacter adhaerens HP15

 Score =  482 bits (1240), Expect = e-140
 Identities = 266/576 (46%), Positives = 353/576 (61%), Gaps = 27/576 (4%)

Query: 15  VEDLERLADLLATHDIAYHQEDNPTVSDAEYDALKRRNLDIETRFPHLVRDNSPSMRVGA 74
           ++ +E L   +  H+  Y+  D+P V DAEYD L R    +ET +P L  D SP+ RVG+
Sbjct: 9   IQRVEELRSAIDDHNYRYYVLDDPRVPDAEYDRLFRELQGLETDYPELASDTSPTRRVGS 68

Query: 75  TRAEQFAPVEHGVPMLSLDNAFSNDEAIEFDARVRRFLRISPSETVAYTAEPKIDGLSAS 134
                F  V H +PMLSLDNAFS DE  +FD RV+   R+  +E V Y  EPK+DGL+ S
Sbjct: 69  AAETSFEEVVHRLPMLSLDNAFSEDELRDFDRRVKD--RLGITEDVEYVCEPKLDGLAVS 126

Query: 135 LRYEKGVLVQGATRGDGRVGEDVTANLRTIADIPHRLKGSGWPDVIEVRGEVYVELAAFA 194
           L YE G L   ATRGDG  GED+TAN+RTI  +P +L+G   PD++EVRGEVY+    F 
Sbjct: 127 LHYENGALTTAATRGDGYSGEDITANIRTIPSVPLKLRGDDVPDLVEVRGEVYMPKDGFE 186

Query: 195 AFNKAAEEAGQRTYANPRNFAAGSLRQIDPKISAQRPLRFFGYAWGLVSEGFA-DSQWGA 253
             N+   E G++T+ NPRN AAGSLRQ    ++A+RPL    Y+  +  E    D+QW  
Sbjct: 187 QLNRRLAERGEKTFVNPRNAAAGSLRQKKSTVTARRPLEMCAYSVAVTDESLLPDTQWEG 246

Query: 254 LERLAEWGFVTTAPPAQRVLNAQGLLDIYAQFEVLRPTLGFDIDGVVYKVDDLELQRRLG 313
           L+R+  WGF    P  ++   A+  L+ Y++    R  L ++IDG+V+KV+ L+ Q+ LG
Sbjct: 247 LKRVQSWGFRIN-PEMRKARGAEECLEAYSELMDKRDGLPYEIDGIVFKVNRLDQQKALG 305

Query: 314 FVSRSPRWAIARKFPAQRARTVLEAIDLQVGRTGAITPVARLKPVTVGGVSVTNATLHNG 373
           FVSR+PRWAIA+KFPAQ   TV+E ++ QVGRTGA+TPVARLKPV VGGV+V+NATLHN 
Sbjct: 306 FVSRAPRWAIAQKFPAQEELTVIEDVEFQVGRTGAVTPVARLKPVFVGGVTVSNATLHNM 365

Query: 374 DEIARLDVRVGDTVVIQRAGDVIPQIVEVALDARPDPAPPPYEFPHVCPCPLQTPLAREV 433
           DEI RLDV +GDTV I+RAGDVIPQ+V+V  + RP  A    E P  CP      +  E 
Sbjct: 366 DEIRRLDVHIGDTVFIRRAGDVIPQVVKVVAEKRPSGA-REVELPRQCPVCDSDVIQIEG 424

Query: 434 TASGQESVVRRCTGEFACPFQRVEHLRHFVSRRAFDIEGLGEKQLQAFFEEGWITEPADI 493
            A      V RC+G   CP QR E +RH+ SR+A DIEGLG+K +    ++G +   AD+
Sbjct: 425 EA------VARCSGGLFCPAQRKEAIRHYASRKALDIEGLGDKWIDIMVDQGMVETVADL 478

Query: 494 FKLARDAEKLAVLREREGYGETSVANLVKGIEARRTIGMDRMIYGLGARDIGETTSTVLA 553
           ++L  D      L + E  GE S ANLV  I+  R   + R +Y LG R++GE T+  LA
Sbjct: 479 YRLTTDD-----LVKLERMGEKSAANLVAAIDRARNPVLWRFLYALGIREVGEATAKALA 533

Query: 554 RNFDRFEDLQAAAEAAARALPGETYLELSTAPGVGP 589
            +F   E + AA E +           L T P VGP
Sbjct: 534 GHFGTLEAIAAADEES-----------LQTVPDVGP 558



 Score = 92.8 bits (229), Expect = 5e-23
 Identities = 76/218 (34%), Positives = 104/218 (47%), Gaps = 40/218 (18%)

Query: 586 GVGPKALDMLVEAGKGGVVADPWPQTDDLELKIGH-----------AVPKLTKP------ 628
           G+G K +D++V+ G    VAD +  T D  +K+             A+ +   P      
Sbjct: 457 GLGDKWIDIMVDQGMVETVADLYRLTTDDLVKLERMGEKSAANLVAAIDRARNPVLWRFL 516

Query: 629 -----------ARAALAQRYGTWDAFADGLVAAASGAPGDDYLHLAAIDGVGPVAAQSLA 677
                         ALA  +GT +A     +AAA      D   L  +  VGP+ A  + 
Sbjct: 517 YALGIREVGEATAKALAGHFGTLEA-----IAAA------DEESLQTVPDVGPIVAGHIR 565

Query: 678 RFFAEDHNRQKVANL-VAELDIQPVAKPKTDTAVAGKTIVFTGSLEKMTRDEAKAQAEGL 736
            FF + HNR+ +  L  A +  Q     + +  + G+T V TG+L  MTRDEAK + E L
Sbjct: 566 SFFEQTHNRETLDALREAGVRWQEEEVREGEKPLKGQTWVLTGTLSGMTRDEAKEKLESL 625

Query: 737 GAKVASSVSKKTDLVVAGPGAGSKLKTATDLGIQVMTE 774
           GAKVA SVSKKT  VVAG  AGSKL  A  L + V+ E
Sbjct: 626 GAKVAGSVSKKTACVVAGEAAGSKLAKAEQLEVPVLDE 663