Pairwise Alignments
Query, 1544 a.a., ATP dependent helicase, Lhr family from Paraburkholderia bryophila 376MFSha3.1
Subject, 1513 a.a., Probable ATP-dependent helicase Lhr (large helicase-related protein) from Mycobacterium tuberculosis H37Rv
Score = 659 bits (1701), Expect = 0.0
Identities = 516/1566 (32%), Positives = 736/1566 (46%), Gaps = 212/1566 (13%)
Query: 39 RAAAHDALAGFHPAVAGWFLKSFPAPTDAQAAAWPQIRQGRSTLVAAPTGSGKTLTAFLS 98
R A AL+ F WF +F APT AQA+AW I G +TLV APTGSGKTL AFL
Sbjct: 2 RFAQPSALSRFSALTRDWFTSTFAAPTAAQASAWAAIADGDNTLVIAPTGSGKTLAAFLW 61
Query: 99 ALDDLVQQGLANNGALPDETLVVYVSPLKALSNDIRLNLQVPLQGIAAELDARGLPPLDI 158
ALD L G P T V+YVSPLKAL+ D+ NL+ PL G+ + +GLP I
Sbjct: 62 ALDSLA--GSEPMSERPAATRVLYVSPLKALAVDVERNLRTPLAGLTRLAERQGLPAPQI 119
Query: 159 RTAVRTGDTTQQERNALKKRAPHILVSTPESLYVLLGSDSGRRMLCTVRTVIVDEIHALA 218
R VR+GDT R L + P +L++TPESL+++L S + R+ L V+TVI+DEIHA+A
Sbjct: 120 RVGVRSGDTPPALRRQLVSQPPDVLITTPESLFLMLTS-AARQTLTGVQTVIIDEIHAIA 178
Query: 219 GSKRGSHLALSLERLDALCGRR-LPRIGLSATQKPVSAVARFLVGGAPVDSDIPADCAII 277
+KRG+HLALSLERLD L RR RIGLSAT +P +ARFL G +P P +
Sbjct: 179 ATKRGAHLALSLERLDDLSSRRRAQRIGLSATVRPPEELARFLSGQSPTTIVAPPAAKTV 238
Query: 278 DVGHIRERDLALEIPPVPLEAVMPNEVWERVYDRLAELVALHSTTLIFVNTRRMAERAAR 337
+ L++++P + + N +W V RL +L+ H++T++F N+RR+AER
Sbjct: 239 E--------LSVQVPVPDMANLTDNTIWPDVEARLVDLIESHNSTIVFANSRRLAERLTA 290
Query: 338 HLTE--------RLGKDA-------------------------VAAHHGSLAKEHRFDAE 364
L E L D AHHGS++KE R E
Sbjct: 291 RLNEIHAARCGIELAPDTNQQVAGGAPAHIMGSGQTFGAPPVLARAHHGSISKEQRAVVE 350
Query: 365 QRLKRGELRVLIATASLELGIDIGDVDLVCQMGSPRAIAPFLQRVGRSGHHVGGMPKGRL 424
+ LKRG+L+ ++AT+SLELGID+G VDLV Q+ +P ++A LQR+GR+GH VG + +G L
Sbjct: 351 EDLKRGQLKAVVATSSLELGIDMGAVDLVIQVQAPPSVASGLQRIGRAGHQVGEISRGVL 410
Query: 425 FPTSRDDLIECAALLDCVRRGELDALRIPRAPLDVLAQQIVAEVSSTEWSEDALFDLIRR 484
FP R DL+ CA + + GE++ +R+P PLD+LAQ VA + DA FD +RR
Sbjct: 411 FPKHRTDLLGCAVSVQRMLAGEIETMRVPANPLDILAQHTVAAAALEPLDADAWFDTVRR 470
Query: 485 AAPYAELAREQYDAVLRMLAEGYTSRN----GPRAAYIHRDVVSGTLRGRRGGKLVAVTS 540
AAP+A L R ++A L +L+ Y S PR Y D +GTL R G + +AVTS
Sbjct: 471 AAPFATLPRSLFEATLDLLSGKYPSTEFAELRPRLVY---DRDTGTLTARPGAQRLAVTS 527
Query: 541 GGTIPENADYAVVLEPQAVN-IGTVNEDFAVESLAGDVFQLGNASYRILRIESGRVRVED 599
GG IP+ +AV L + + +G ++E+ ES GDV LG S+RI I RV V
Sbjct: 528 GGAIPDRGLFAVYLATERPSRVGELDEEMVYESRPGDVISLGATSWRITEITHDRVLVIP 587
Query: 600 AQGQPPNIPFWLGEAPGRSDELSFGVARLREQIARLLASGDDATTPLDNAQASDTASKAT 659
A GQP +PFW G+ GR EL + L ++A L
Sbjct: 588 APGQPARLPFWRGDDAGRPAELGAALGALTGELAAL------------------------ 623
Query: 660 ASEYVPDATAEAPNPMPARLERAIDWLIAELGLDEAAARQIVDYLARARAALGVLPTQDT 719
D TA A LG D+ A + L R A V+PT T
Sbjct: 624 ------DRTAFGTR-------------CAGLGFDDYATDNLWRLLDDQRTATAVVPTDST 664
Query: 720 LVMERFFDESGGTQLVVHAPFGSRVNRAWGLALRKRFCRQFNFELQAAATEDAIVLSL-- 777
L++ERF DE G ++++H+P+G RV+ LA+ +R ++ + + A+++ IV+ L
Sbjct: 665 LLVERFRDELGDWRVILHSPYGLRVHGPLALAVGRRLRDRYGIDEKPTASDNGIVVRLPD 724
Query: 778 ---------TGSHSFVLDEVWRYLHSNSAERLLIQALLDAPLFGVRWRWNATTALGLPRY 828
G+ FV D ++ + ++ + + LF R+R +A AL LPR
Sbjct: 725 TVSAGEDSPPGAELFVFD-------ADEIDPIVTTEVAGSALFASRFRESAARALLLPRR 777
Query: 829 TGGRKTAPQLQRMRSEDLLTSVFPEQAACLENVVGERELPHHPLVDQTVDDCLHDAMDSE 888
GR++ QR R+ LL R+ P P+V +TV +CL D D
Sbjct: 778 HPGRRSPLWQQRQRAARLLEVA--------------RKYPDFPIVLETVRECLQDVYDVP 823
Query: 889 RWLALLRRMENGDVRLVARDLPAPSPLAAEIL--NAKPYAYLDDAPIEERRTQAVLNRRW 946
+ L+ R+ VR+ + PSP AA +L + Y D P+ ERR A+
Sbjct: 824 ILVELMARIAQRRVRVAEAETAKPSPFAASLLFGYVGAFMYEGDTPLAERRAAAL---AL 880
Query: 947 TDPASADDLG------ALDADAIASVRDE-----AWPQARSIDEMHEALTGLACITEAEA 995
A+ LG LD D IA+ + A AR + + + L L +TE E
Sbjct: 881 DGTLLAELLGRVELRELLDPDVIAATSRQLQHLAADRVARDAEGVADLLRLLGPLTEDEI 940
Query: 996 QHNEGWPE---WLASLARSGRATRIEIAADAALWLPAERLTCFDALYRSRNSGTTNSGPR 1052
G PE WL L + RA + A + W+ E + G G
Sbjct: 941 AARAGAPEVSGWLDGLRAAKRALVVSFAG-RSWWVAVE------------DMGRLRDGVG 987
Query: 1053 FTPPLTAPKGYTDEWSADDALLDVLRARLTGFGPLPADAIADALKLPRTSVEQALGRLEA 1112
P+ P +T+ + D L ++L P A A L LGRL +
Sbjct: 988 AAVPVGLPASFTE--AVADPLGELLGRYARTHTPFTTAAAAARFGLGLRVTADVLGRLAS 1045
Query: 1113 EGYVMRGRFTP----NTSEEEWCERHLLARIHRYTVKRLRREIEPVERHDFMRFLFEWQH 1168
+G ++RG F + E+WC+ +L + R ++ LR + EPV + RFL WQH
Sbjct: 1046 DGRLVRGEFVAAAKGSAGGEQWCDAEVLRILRRRSLAALRAQAEPVSTAAYGRFLPAWQH 1105
Query: 1169 LTPDTRSEGRDALAAVLEQMEGFEAAASAWEEDILPARVKAYSNTSLDELCRSGKIVWTR 1228
++ + G D LAAV++Q+ G ASA E +L R++ YS LDEL SG + W+
Sbjct: 1106 VS--AGNSGIDGLAAVIDQLAGVRIPASAIEPLVLAPRIRDYSPAMLDELLASGDVTWSG 1163
Query: 1229 LTERSRS----AAGPVRSTPIVLLPRPQVRTWSALIDAERQPELSARAQSVYDALSQHGA 1284
S S A P S P+ L ++ DA R ++ +L GA
Sbjct: 1164 AGSISGSDGWIALHPADSAPMTLAEPAEI----DFTDAHR---------AILASLGTGGA 1210
Query: 1285 MFFDELLHELRVLRIELESALGELVAAGLVNSDSFAGLRALLKPAAKRN----AYSGSRR 1340
FF +L H+ + EL++AL EL+ AG V D+FA +RA+L A R A+ G R
Sbjct: 1211 YFFRQLTHD-GLTEAELKAALWELIWAGRVTGDTFAPVRAVLGGAGTRKRAAPAHGGHRP 1269
Query: 1341 ARSSMGLGALIGGMDDAGRWALVNRRASIATSEETAAQPGRPQQQRRRQLPAETLEHVAM 1400
R S R+ L + +A A P + L A + A
Sbjct: 1270 PRLS--------------RYRLTHAQARNADPTVAGRWSALPLPEPDSTLRA---HYQAE 1312
Query: 1401 TLLRRYGVVFWRVLEREADWLPPWRDLLRVYQRLEARGVIRGGRFVNGLAGEQFALPEAI 1460
LL R+GV+ + E + L +V E G + G F+ L G QFA+ +
Sbjct: 1313 LLLNRHGVLTKDAVAAEG-VAGGFATLYKVLSAFEDAGRCQRGYFIESLGGAQFAVASTV 1371
Query: 1461 PLLRE----VRRHANDGAFVCVGGTDPLNLVGTLLVGERVPAVAGNRVLYRDGVVIATLA 1516
LR V D V + DP N G L A R + G ++ +
Sbjct: 1372 DRLRSYLDGVDPEQPDYHAVVLAAADPANPYGAALPWPASSADGTARPGRKAGALVVLVD 1431
Query: 1517 AGAFWF 1522
WF
Sbjct: 1432 GELAWF 1437