Pairwise Alignments
Query, 1062 a.a., Multidrug efflux pump subunit AcrB from Paraburkholderia bryophila 376MFSha3.1
Subject, 1024 a.a., acriflavin resistance protein (RefSeq) from Shewanella sp. ANA-3
Score = 340 bits (873), Expect = 2e-97
Identities = 264/1040 (25%), Positives = 487/1040 (46%), Gaps = 39/1040 (3%)
Query: 3 IVNVALKRPYTFIVMAILIVLATPFVLFTTPVDVLPEINIPVVSIIWTYNGLSAEDMAHR 62
I+ A+ R + V+A + + L PVD LP + P++ + + G + ED+
Sbjct: 2 IIKAAISRRISTAVLAFGLAIFGALNLNMLPVDFLPSVKYPLIKLSIIWQGATPEDIDQN 61
Query: 63 IASVNERSLTTTVNDIEHIESQSLAGITILKVFLQPTANIQTAIAQTVAVEQAQLKQMPP 122
+A ER L + V+ ++++ S ++ G+ L V + ++ A T+A K +P
Sbjct: 62 LADPIERELAS-VDGLDYLSSSAIEGLYQLDVNYRYGVDVDVAYQDTLAAFNRSTKNLPV 120
Query: 123 GATPPLVISYSASSIPVIQLGLSSTKLSEQQLNDTALNFLRPQLVTIPGAAVPYPYGGKS 182
P++I S +P++Q S + QL ++L +L++ G A GG
Sbjct: 121 DIEAPVIIKADPSQLPIVQAVFESESMDLTQLRTWIDSWLTQRLLSASGVAAIDVAGGLE 180
Query: 183 RLISVDLNTRALLSKGLTPLDVVSAFNAQNLILPTGTAKIGPKEYTINMNGSPATLEGLN 242
R I + ++ L + GL + +A+NL G +E + + G + L +
Sbjct: 181 REIRIFVDDEKLEAHGLDLTTLERVLSAENLQRVGGRVTGKYRENIVRVMGEFSQLAVIQ 240
Query: 243 DIPV-RTVNGATTYLREVAHVRDGFSPQTNIVRENGHRGVLMSVLKNGSASTLSIVNTLH 301
D+ + R +G+ +R+VA V+D + R NGH V ++V+K A+T++ V+ +
Sbjct: 241 DLVLSRDSSGSIVRIRDVAEVKDSHEDIRMLTRLNGHPAVKVNVIKQADANTVTTVDNVE 300
Query: 302 GLLPAARAALPPDLKITALFDQSVFVKAAVQGVVREAVVAAALTAAMILLFLGNWRSTCI 361
L + P D+K T + +Q+ ++ +++GV A+ A AL ++ +FLGN R I
Sbjct: 301 DRLADLAPSFPKDIKFTLVENQADYINDSIRGVRNTALEAMALVVLVLFVFLGNSRQVLI 360
Query: 362 IAISIPLSILSSLIALHALGQTINIMTLGGLALAVGILVDDATVTIENIE--RHLHMGTN 419
IAI++P ++L + +H G ++NI +LGGL +A+G+L D + + +ENI R LH N
Sbjct: 361 IAIALPFALLVNFFLMHLAGFSLNIFSLGGLVVAIGVLPDTSIIVVENISRLRSLHDKAN 420
Query: 420 LHDAILEGAGEIAIPALVSTLCICIVFVPMFFLTGVARYLFVPLAEAVVFAMLASYVLSR 479
E E+ + +T+ +FVP + G+ LF L ++ M+ + + +
Sbjct: 421 PQSISEEATLEVGGAIMAATVTFIALFVPFLLVPGLITLLFKELVLVILGLMIIAGLAAI 480
Query: 480 TLVPTLAMLLMGHAHKPKADMKPSLFARLYRRFDNGFERMRAAYIVILSSLLVRRARFGS 539
TL P L +L+ KA+ + F+ + ++G +R AY +L S L R
Sbjct: 481 TLTPMLGGVLL------KANQREFAFS---EKINHG---LRWAYGALLHSALQFRLTTIF 528
Query: 540 IFLGFCVVSMGLAFVLGEDFFPSVDAGNIRLHMRAPTGTRIEETARLADEVEKVIREVVP 599
IF+G + + L G +FFP+VD G I + +R P G + +A +VE + V+
Sbjct: 529 IFIGVAIGGVLLFKSAGSEFFPAVDDGRIVVKIRMPAGANLARMDAIAQQVEAL---VIG 585
Query: 600 EKELGTILDNLGLPYSGINLSYSNAGTIGTLDGEIQIALKEGHE---PTQLYVDKLRAML 656
++ + ++ G G+ Y+N IG +GE+ I L E T Y+ +LR +
Sbjct: 586 DQRVRSVFTLSGGAVRGL---YTN--KIGN-EGEVDIELVPSSERKITTTEYIKELRPKV 639
Query: 657 PQRF-PGVEFFFQPADIVTQILNFGLPAAVDIQIAGADQQGNFDVARKLLKQVRMIPGTV 715
+ PG A + I + G A ++++I G++ FDVA KL ++ P
Sbjct: 640 AKLLAPGAILAVNQAK-MRGIRSVG-QAEIEVEINGSEVDTLFDVANKLAAKLAERPELT 697
Query: 716 DTHIQQKLDEPAINLQMDRTRLQQLNLTASNVAQNVLISLSGSSQTSPGFWYNDRNGVEY 775
+ ++ +P + +DRT + L+ +A + ++GS T Y + + + Y
Sbjct: 698 NVYVSLDSSKPEWQVDIDRTLAAEHGLSTKEIAHVLNGYINGSVPTR----YREASEL-Y 752
Query: 776 NVAVQTPQYSISSIDDLLRTPVSASATGPTQLLGNLVRVQPQNQFAVVTHYNIRPVIDLY 835
++ + P+ + S D+ + A+ +G L ++ +V + N + +
Sbjct: 753 DIRIIMPESQLRSRSDVENISI-ATPSGHYVRLKDVAKVTAATGPVEIIRKNQIKQVIVR 811
Query: 836 VSVDKRDLGSVADQVDKLVEQARASLPRGSQITVRGQVQTMRSSYFGLGLGVAMAIVLVY 895
DL S + V ++ + + P G ++ G+ M + + A+ +
Sbjct: 812 CDPSATDLNSAKELVTNILTE--TTWPTGYTYSIGGKALQMTQMQTTVQSILGYAVFFSF 869
Query: 896 LLIVVNFQSWVDPLIIVSALPAALAGIVWMLFLTGTHLSVPALTGAIMTMGVATANSILM 955
+++ V F + PL+I+ A P L GI + LF + A++ + + +L+
Sbjct: 870 IVLAVQFNNLRLPLVILFAAPFCLTGIGYGLFFASQPFGATVIIAAMIVLAANVIDGVLL 929
Query: 956 VAFARQRLSAGAPPLTAALEAGASRIRPVLMTAFAMIIGMIPMALGLGEGAEQNAPLGRA 1015
+ A ++ G L A +AG SR+RP LMT ++G +P+AL EG E P+ A
Sbjct: 930 IQTAERQKQQGITLLKATFDAGLSRLRPRLMTVLPAVLGFMPLALAFEEGGELLRPMAAA 989
Query: 1016 VIGGLLFATVSTLFFVPLVF 1035
IGGLL LF VP+++
Sbjct: 990 AIGGLLLNVFVALFLVPVLY 1009
Score = 57.8 bits (138), Expect = 4e-12
Identities = 111/516 (21%), Positives = 210/516 (40%), Gaps = 36/516 (6%)
Query: 525 VILSSLLVRRARFGSIFLGFCVVSMGLAFVLGEDFFPSVDAGNIRLHMRAPTGTRIEETA 584
+I+ + + RR + G + +L DF PSV I+L + T +
Sbjct: 1 MIIKAAISRRISTAVLAFGLAIFGALNLNMLPVDFLPSVKYPLIKLSIIWQGATPEDIDQ 60
Query: 585 RLADEVEKVIREVVPEKELGTILDNLGLPYSGINLSYSNAGTIGTLDGEIQIALKEGHEP 644
LAD +E+ + V L + GL +N Y + D + P
Sbjct: 61 NLADPIERELASVDGLDYLSSSAIE-GLYQLDVNYRYGVDVDVAYQDTLAAFNRSTKNLP 119
Query: 645 TQLYVDKLRAMLPQRFPGVEFFFQPADIVTQILNFGLPAAVDIQIAGADQQGNFDVARKL 704
+ + P + P V+ F+ + L + + + ++ A DVA L
Sbjct: 120 VDIEAPVIIKADPSQLPIVQAVFESESMDLTQLRTWIDSWLTQRLLSASGVAAIDVAGGL 179
Query: 705 LKQVRMIPGTVDTHIQQKLDEPAINLQMDRTRLQQLNLTASNVAQNVLISLSGSSQTSPG 764
+++R+ VD +KL+ ++L T L+++ L+A N+ Q V ++G +
Sbjct: 180 EREIRIF---VD---DEKLEAHGLDL----TTLERV-LSAENL-QRVGGRVTGKYR---- 223
Query: 765 FWYNDRNGVEYNVAVQTPQYSISSIDDLLRTPVSASATGPTQLLGNLVRVQPQNQ-FAVV 823
E V V ++ I DL+ +S ++G + ++ V+ ++ ++
Sbjct: 224 ---------ENIVRVMGEFSQLAVIQDLV---LSRDSSGSIVRIRDVAEVKDSHEDIRML 271
Query: 824 THYNIRPVIDLYVSVDKRDLGSV--ADQVDKLVEQARASLPRGSQIT-VRGQVQTMRSSY 880
T N P + + V + + D +V D V+ + S P+ + T V Q + S
Sbjct: 272 TRLNGHPAVKVNV-IKQADANTVTTVDNVEDRLADLAPSFPKDIKFTLVENQADYINDSI 330
Query: 881 FGLGLGVAMAIVLVYLLIVVNFQSWVDPLIIVSALPAALAGIVWMLFLTGTHLSVPALTG 940
G+ A+ LV L++ V + LII ALP AL +++ L G L++ +L G
Sbjct: 331 RGVRNTALEAMALVVLVLFVFLGNSRQVLIIAIALPFALLVNFFLMHLAGFSLNIFSLGG 390
Query: 941 AIMTMGVATANSILMVA-FARQR-LSAGAPPLTAALEAGASRIRPVLMTAFAMIIGMIPM 998
++ +GV SI++V +R R L A P + + EA ++ I +P
Sbjct: 391 LVVAIGVLPDTSIIVVENISRLRSLHDKANPQSISEEATLEVGGAIMAATVTFIALFVPF 450
Query: 999 ALGLGEGAEQNAPLGRAVIGGLLFATVSTLFFVPLV 1034
L G L ++G ++ A ++ + P++
Sbjct: 451 LLVPGLITLLFKELVLVILGLMIIAGLAAITLTPML 486