Pairwise Alignments
Query, 1353 a.a., two-component system sensor histidine kinase/response (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Subject, 1349 a.a., hybrid sensor histidine kinase/response regulator from Pedobacter sp. GW460-11-11-14-LB5
Score = 831 bits (2147), Expect = 0.0
Identities = 485/1360 (35%), Positives = 756/1360 (55%), Gaps = 54/1360 (3%)
Query: 28 QITFSYISINEGLSQSTVFSIDQDKRGNMWFATYDGVNKYDGYAFTVYQHNEDDPNSIAN 87
Q++F ++S+N GLSQSTV SI +D RG MWF T D +N+YDG + +Y+ + D+P SI+
Sbjct: 7 QLSFDHLSVNNGLSQSTVLSICKDSRGYMWFGTRDCLNRYDGKSVKIYRTDPDNPASIST 66
Query: 88 -DISRIVKTDSQGRVWIGTRDGLSRYDEEKDIFQNFFYE-KNGKHLQVNGIEEISPEQ-- 143
D ++ D Q +WIGT++GL+RY EKD F+ ++ KN + I I ++
Sbjct: 67 EDYIYALEEDRQKNLWIGTQNGLNRYIPEKDAFERIAFDPKNANSISDKIILSIYADRSG 126
Query: 144 -LLISTPEGLIMFDIKES-KFIDDSFSTAMHKTIASTLYRQGD-QIYIGTSTDGLYTYSI 200
+ T +GL M + S KF + T++ I++GT+T GL S
Sbjct: 127 KVWFGTNQGLSMLENGSSRKFKKIYQKDGLAGNSVYTIFEDSKGNIWVGTTT-GLSRLSF 185
Query: 201 TQKTFEKVI--------PILGTKQIQAILQQSPTRIWVATEGAGLFLINPKTKEIKNYLH 252
+ + + I+ I + RIW+ +E GL L P++ K + +
Sbjct: 186 KEGKYHIQSFYHRAGDPGSISGNSIRTIAEDGKGRIWIGSESEGLNLFLPQSHSFKRFRY 245
Query: 253 SPSNPKSISSNYIRSLAMDSQNRLWIGTFNDLNIYHEGTDSFASYSSNPVENGSLSQRSV 312
S P ++S++ +R + D + LWI T N LNI T F SY + SLS S+
Sbjct: 246 SALQPNALSNDIVRKIMPDGKGNLWIATMNGLNILDTQTLGFTSYKHDADNRKSLSDNSI 305
Query: 313 RSIFMDSQGGMWLGTYFGGLNYYHPIRNRFKNIRNIPYKNSLSDNVVSCIVEDKDKNLWI 372
+ IF D QG +W+GT FGG+N H F + Y+NS+S ++ S I D D+NLWI
Sbjct: 306 KEIFQDDQGSIWIGTMFGGVNVAHRNTIPFTVFKYSKYRNSISSDISSVIAADNDQNLWI 365
Query: 373 GTNDGGLNLYNPITQRFTSYTLQEDESARGIGSNNIKAVYVDEKKSLVYIGTHAGGLSIL 432
GT GLN YN T F Y + + + +N IKA++ D +K ++IG + GGL +
Sbjct: 366 GTEGQGLNFYNVKTGLFKKY-INDPRDPGSLSNNTIKAIFND-RKGRIWIGLYQGGLELF 423
Query: 433 HRNSGQVENFNQRNSQLVNENVYAILPDGEGNLWLGTLS-ALVRFNPEQRSFTTIEKEKD 491
++G+ +++ + L + +I D +G L LGT S L F+PE+ SF I+ +
Sbjct: 424 IPSTGKFKHYPPGRNGLSQGYLSSISEDDQGRLLLGTSSKGLNIFDPEKESFQLIDDQPG 483
Query: 492 -GTPVVSKQITTLFRDSHKRLWIGGEEGL----------SVFKQEGLDIQKASILPVSNV 540
G + S I ++D+ K LW+G GL SVF ++ D K S L S +
Sbjct: 484 HGLKLSSSYIRFAYQDTKKNLWVGTPRGLNFLPPGANHFSVFSRD--DKTKGS-LKSSQI 540
Query: 541 TKLFTNCIYEASNGIIWVGT-REGFYCFNEKDKQIKRYNTTNGLPNNVVYGILEDSFGRL 599
T C++E G IWVGT R G ++ K Y GL ++ + +L+D+ G L
Sbjct: 541 T-----CLWEDRLGHIWVGTMRGGLSLYHPDSKSFSTYTRAQGLASDNIIDVLDDNDGNL 595
Query: 600 WLSTNRGISCFNPETEKFRNFTESDGLQSNQFNTASYCRTSVGQMYFGGINGITTFRPEL 659
W+ST+RG+S F+ + F+N+ DGL +N+FN S R G++YFG +G+ F P
Sbjct: 596 WISTDRGLSKFDYKRGVFKNYNTGDGLPTNEFNVNSAYRDIHGKLYFGSYDGLVVFTPRE 655
Query: 660 LLDNPYTPPVVITKLQLFNKVVRPDDETGILTKNISETKSITLKSWQTAFSIEFVVSNYI 719
+ +N P V + L+LFNK V +++ G+L ++IS TK IT + Q FS+EFV NY+
Sbjct: 656 ITENTLIPRTVFSGLKLFNKPVGINEDNGLLKQDISFTKGITFTAEQNIFSLEFVSLNYV 715
Query: 720 SGQHNTFAYKLEGYDKEWYYLTDSRTVSYSNLPQGTYQFLVKAANSDGKWNPIPTALEII 779
Q N +AYKLEG++K+W Y+T + SY+NLP G Y+ LVK +N+DG W+ P +EI
Sbjct: 716 QPQRNRYAYKLEGFEKDWNYVTIP-SASYTNLPSGNYKLLVKGSNNDGLWSKAPVVMEIR 774
Query: 780 VLPIWYKTWWALLIFFATFAGFITFVFRFFWMRKSMEAQLEIERRDKEHQEEINQMKMRF 839
VLP ++TWWA ++F + FV RF ++ ++ +L E + E Q E+ QMK+ F
Sbjct: 775 VLPPLWQTWWAYTLYFIAGGLLLYFVLRFTRRQQKLKTELYYEHLNSERQSELYQMKLDF 834
Query: 840 FINISHELRTPLTLILTPLQEIINKISDRWTRN-QLEYIQRNANRLLHLVNQLMDYRRAE 898
F ISHE+RTPLTLI PL+++I ++ N QL+ I+RN +RL+ L+++L+D+R+ E
Sbjct: 835 FTRISHEIRTPLTLIFAPLEKLIKITAENGAVNLQLQNIKRNTDRLVRLISELLDFRKIE 894
Query: 899 LGVFELKAKKGNAHQLIQDNFLFYDKLARHKKITYTLHSELEDKEVLFDANYLELIVNNL 958
G LK + + + + Y LA K I Y E E V +D +E + N+
Sbjct: 895 SGNLSLKVSENDLVSFCRQIYESYLGLAEIKNIDYRFECEAESMLVYYDPAQMEKVFYNI 954
Query: 959 LSNAFKYTESGQSITVTLKEENGWLLLQVSDTGIGIPINKQGKIFERFYQIESEHV---G 1015
LSNAFK+T IT +LK+ +G + ++DTGIGIP + Q KIF F+Q+++ G
Sbjct: 955 LSNAFKFTPDNGKITFSLKQSDGLAKIAITDTGIGIPADLQDKIFTNFFQVKNGAAATEG 1014
Query: 1016 SGIGLSLVQRLIELHHGRIELDSEENKGSTFSVYLPQDLSVYKPSELASNNEQNEEE--- 1072
GIGL+L + +++LH G + + SE Q +++ S L N ++E+
Sbjct: 1015 WGIGLALAKNILDLHKGEVNVYSEPANNKR------QGITILHVSLLLGKNHFSDEQIAS 1068
Query: 1073 -QVYSTNSKAMYFIDTEKVENESVESGDKKRGTILIVEDNNEIRRYLSNGLADLFNTLEA 1131
+ + A+ +D E + + V DKKR T+L+VEDN+E+R ++ L ++ LE
Sbjct: 1069 NPIVTDKPVAVGSLDHELAKIQLVAPEDKKRHTVLVVEDNDELRDFIVQSLKHTYHILEG 1128
Query: 1132 GNGEEALEKLKDNEVDVIVTDVMMPVMDGIKLCKNVKQNIRTCHIPVIILSAKTDIKDQM 1191
NG E ++ D++V+DV MP ++G +LC+ +KQ T HIPVI+L+A Q+
Sbjct: 1129 KNGLVGWEVATEHVPDIVVSDVTMPELNGFELCQRLKQEETTNHIPVIMLTAMASHVHQI 1188
Query: 1192 EGLQMGADDYIPKPFSLAILTTKIQNMMRTRRRMLDKYAKSLEVEPEKITFNAMDEALLK 1251
+GL+ GAD YI KPFS+ +L I+N+++ R + KY K + + P K+ + +E L
Sbjct: 1189 DGLEAGADVYITKPFSIQVLELSIRNLLQGREELRQKYIKQIMLNPRKLETASPEEKFLN 1248
Query: 1252 RAMAIVEKNMDNIEFSTDEFAREMNMSRSNLHLKLKAITGESTIDFIRKIRFNEAAKLLK 1311
R M ++E M++ EF+ ++ MS++ L+ K+KA+TG S DFI+ R AA+LL
Sbjct: 1249 RLMQLIEDGMEDPEFNVGGLVDQIGMSQTVLYKKIKALTGLSISDFIKSQRLKRAAQLLN 1308
Query: 1312 DGRYTVAEVSTMVGFNTPSYFATSFKKYFGCLPTEYIKKS 1351
D + +AEV+ VGFN YF+ F+K FG P+EY +K+
Sbjct: 1309 DHKMNIAEVAYSVGFNDRKYFSKEFRKQFGVAPSEYQQKT 1348
Score = 84.3 bits (207), Expect = 7e-20
Identities = 81/331 (24%), Positives = 144/331 (43%), Gaps = 24/331 (7%)
Query: 17 GMHSAFSETPEQITFSYISINEGLSQSTVFSIDQDKRGNMWFATY-DGVNKYDGYA--FT 73
G++ A T F Y +S I D N+W T G+N Y+ F
Sbjct: 324 GVNVAHRNTIPFTVFKYSKYRNSISSDISSVIAADNDQNLWIGTEGQGLNFYNVKTGLFK 383
Query: 74 VYQHNEDDPNSIANDISRIVKTDSQGRVWIGT-RDGLSRYDEEKDIFQNFFYEKNG-KHL 131
Y ++ DP S++N+ + + D +GR+WIG + GL + F+++ +NG
Sbjct: 384 KYINDPRDPGSLSNNTIKAIFNDRKGRIWIGLYQGGLELFIPSTGKFKHYPPGRNGLSQG 443
Query: 132 QVNGIEEISPEQLLIST-PEGLIMFDIKESKF--IDDSFSTAMHKTIASTLYRQGD---Q 185
++ I E +LL+ T +GL +FD ++ F IDD + + + + D
Sbjct: 444 YLSSISEDDQGRLLLGTSSKGLNIFDPEKESFQLIDDQPGHGLKLSSSYIRFAYQDTKKN 503
Query: 186 IYIGTS------TDGLYTYSITQKTFEKVIPILGTKQIQAILQQSPTRIWVATEGAGLFL 239
+++GT G +S+ + +K L + QI + + IWV T GL L
Sbjct: 504 LWVGTPRGLNFLPPGANHFSVFSRD-DKTKGSLKSSQITCLWEDRLGHIWVGTMRGGLSL 562
Query: 240 INPKTKEIKNYLHSPSNPKSISSNYIRSLAMDSQNRLWIGTFNDLNIYHEGTDSFASYSS 299
+P +K Y + + ++S+ I + D+ LWI T L+ + F +Y
Sbjct: 563 YHPDSKSFSTY----TRAQGLASDNIIDVLDDNDGNLWISTDRGLSKFDYKRGVFKNY-- 616
Query: 300 NPVENGSLSQRSVRSIFMDSQGGMWLGTYFG 330
N + ++ +V S + D G ++ G+Y G
Sbjct: 617 NTGDGLPTNEFNVNSAYRDIHGKLYFGSYDG 647
Score = 40.4 bits (93), Expect = 1e-06
Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Query: 26 PEQITFSYISINEGLSQSTVFSIDQDKRGNMWFATYDGVNKYDGYAFTVYQHNEDDPNSI 85
P+ +FS + +GL+ + + D GN+W +T G++K+D Y V+++
Sbjct: 565 PDSKSFSTYTRAQGLASDNIIDVLDDNDGNLWISTDRGLSKFD-YKRGVFKNYNTGDGLP 623
Query: 86 ANDIS-RIVKTDSQGRVWIGTRDGL 109
N+ + D G+++ G+ DGL
Sbjct: 624 TNEFNVNSAYRDIHGKLYFGSYDGL 648