Pairwise Alignments
Query, 1431 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Subject, 1374 a.a., hypothetical protein from Pedobacter sp. GW460-11-11-14-LB5
Score = 488 bits (1255), Expect = e-141
Identities = 374/1377 (27%), Positives = 635/1377 (46%), Gaps = 200/1377 (14%)
Query: 183 DSPGHVWIGTKQGLWKYHDGKLEAMDTQGESWEHIFSYDQYTCIITGKKEIYRHSLSNNR 242
D G +W+GT+ GL K+ DG +++ Y I TG SL+NN
Sbjct: 59 DKRGFIWVGTENGLCKF-DG---------------YAFKIYVNI-TGDTT----SLTNNY 97
Query: 243 LEKIASLTELGDTGVITGSLRLQHQWVMFTATGSYILDPVTGKLRRF-----SRLNIKNG 297
+ + GV WV T G DPVT K RF +R ++ N
Sbjct: 98 INAVVE----DKNGVF---------WVG-TMNGLNKFDPVTEKFERFYHKENNRTSLSNN 143
Query: 298 NVTR---DNKGNAWVHNYTG-NVWYVNTSTGDIKHFQFLSSEHLGYIDVERYSIIHDSRD 353
+ D WV G N++ N++ + F + + V +I D
Sbjct: 144 KIWSLLIDRTNKLWVGTDDGFNLFNKNSNAFTVYQPDFKDPDAIKGKSVN--AIAEDKAG 201
Query: 354 IIWITTYGNGLFAYDLNTGDLQHFTFEVSHSSHINSNYLQYIIEDRSGGIWVSSEFSG-- 411
+W+ + GL +D T +++T + + N N + + D G IW+ S + G
Sbjct: 202 NLWLGNWSKGLNKFDKKTKSFKNYT-QKEVAGEKNPNDIWTLCLDADGMIWIGSYWKGDL 260
Query: 412 --------------------LSHLEILNKGTLRIYPNGEDASDRSNTIRMLLRGKNGNVY 451
S +LN GT ++ G NT +
Sbjct: 261 FRFDPKSESFTTYASKGTGNASIFSVLNLGTEKLLVGGSAGVFWVNTKLNKWEKIEELEF 320
Query: 452 MANRMGTLYEYDADLKNILRREKFTHNVYSMCEDNEGQLWLGMRGIG--LRIGADQW--- 506
AN G LY + + I + F+ ++ + N L G I + G D W
Sbjct: 321 FAN--GGLYRDKSGMIWICGKNGFSKIDFNQYKFNFISLPFGQAEIKSIISYGKDFWVGT 378
Query: 507 ----YRYNSKDN-----------NSLSNDNVYLIYRDRKGRMWIGTFGGGLNLAVKTGNG 551
++YN ++ NSLS+ + + D K R+W+ G K
Sbjct: 379 NKGLFKYNPDNHAVSKLQHTGNPNSLSSSEIINLSTDLKNRLWVMGENGFDRYDEKANKF 438
Query: 552 YQFKH------FFQDSYGEKRVRVIQEDRNGMMWVGTNNGIYIFHPDS-----LINSPKN 600
H FF + + V ++ ++ T+ G+ +++ + N PKN
Sbjct: 439 IHHHHRSALGSFFNEDVFRDLIEVNADE----YYLATDAGLKVYNDKTNSYTHYFNDPKN 494
Query: 601 YVLYNHVNETFPSNEIRCLVNDHEGNMWIGTTGAGFAICYPG------------------ 642
+ +N + CL+ D +GN+WIGT G+G + P
Sbjct: 495 QA-------SLSNNHLYCLLKDAQGNVWIGTYGSGLSRFNPKTRKFSNYMINNSKRGGIS 547
Query: 643 ---------NDYQHL----------------TFDCYSIKDGLPNGVIQSIVEDQDNKMWI 677
+ +Q++ TF+ YS ++G + V +VED + ++W+
Sbjct: 548 NNIVNSLYLDSHQNVWVCTRDGLNKYIAKTNTFEIYSKQNGFASNVFTDLVEDNNGRLWV 607
Query: 678 ATEYGISRFTLATKQIENYYFSSHTLGNVYSENTACINADGRLLFGTNYGLVVLDANKVE 737
TE GIS F +K ++NY VY+ C NA G + + G+V + ++
Sbjct: 608 TTEQGISLFDPVSKMVKNY----DEKDGVYANAAICKNAKGEIYLAGSKGIVYFNPQLLK 663
Query: 738 NMEKLASTVFTGLHINGAHMLPGMDDSPLNETMSYTGQLNLKHYQNSFVIAFSTFNF-LS 796
+ + F+ I +LPG DDSPL + T ++ L + Q+ F N+ LS
Sbjct: 664 YNKTAPAVYFSDFSIFNKLILPG-DDSPLKLPVYMTREITLPYSQSVLSFGFVALNYTLS 722
Query: 797 GASKYSYRMPPYDSEWSIPSAQNLATYRNLPPGKYQLQVKACNVAGVWGEE-STMEIVIA 855
+KY+Y + +D +W+ +++ TY NL PGKY L+V+A N G+W E +++ I I
Sbjct: 723 EKNKYAYFLEGFDKKWNYSGSEHKVTYTNLNPGKYVLKVRASNNDGIWNMEGNSIGITIT 782
Query: 856 PPFWQTTWAYLIY-LVFIGIV-CYFSFHIIRKFNRLRNRIA-----VEKQLTEYKLEFFT 908
PP+++T WA+ IY L F G++ Y + R + ++A EK+L+E KL FFT
Sbjct: 783 PPWYRTWWAFCIYGLTFFGMIYAYLKYREHRANLEFQVKLAHVESEKEKELSEKKLSFFT 842
Query: 909 NISHEFRTPLTLIQGALNKLINIENPPKEMQRPLKTMDKSTQRMLRLINQLLEFRKMQKN 968
N+SHEFRTPLTLI + +L+ +N L + ++ +R+L L++QLL FRK
Sbjct: 843 NVSHEFRTPLTLIINPVKELL-YKNDKNVDTTDLNIVYRNAKRLLSLVDQLLLFRKADTY 901
Query: 969 KLALSLEETDVIAFLYEIFLSFKDTSESKNIDFSFEPSQPAYKMFIDKGNLDKVTYNLLS 1028
L + ++++ E+FL F + SKNI F + + D+ ++ V +NLLS
Sbjct: 902 GEKLKVAPVNLVSLCKEVFLCFVHQARSKNIVLDFIGTDEVIPFYADREKIEIVFFNLLS 961
Query: 1029 NAFKYTPSNGKIIFKIDIQEDKQQLRIQVIDNGIGIPKEKRSELFKRFMQSSFSHSS--- 1085
NA K+TP G + K+ + + +++ + D G GI +L+++F Q + S+
Sbjct: 962 NAIKFTPEGGTV--KMIVGNRGEDIQVGIEDTGCGITTVAGEKLYEKFYQDPGNKSAKGG 1019
Query: 1086 VGVGLHLTHELVQVHKGNISYDENEGGGSVFTVLLPTNSDIYQEKDFLIPNQLLTEEEEQ 1145
G+GL+L +++H G I+Y E G++F + L I KD +I + L + +
Sbjct: 1020 FGIGLYLAKNFIEMHGGTINYTSTENKGTIFNISL--RRGISHFKDAVILQEALVDTDSS 1077
Query: 1146 HSKDFLRNETS-----EDTFQPPVDP---LNKRKVLIIEDDTDIREFLREEIGVYFEVEV 1197
K+ + +E + E +P +D L+ + +LII+D+ +IRE+L++ + + +
Sbjct: 1078 LFKELIEDEITANKIVEAAEEPLIDSQLALDLKTLLIIDDNIEIREYLKQVFRMDYHLYE 1137
Query: 1198 AADGTSGFEKASTYDADLIVCDVLMPGMNGFEVTRKLKNEFTTSHIPIILLTALNIEEKY 1257
A +G G++ D+++CDV+M G+ G E+ K+K + SHIPIILLTA++ E
Sbjct: 1138 AGNGEDGYDMVKELLPDIVICDVMMDGITGIELCSKIKEDVAVSHIPIILLTAISAPEVK 1197
Query: 1258 QEGIESGADAYITKPFNVSLLLARIFKLIELRDKLRQKYSNEPGLAHSIICTNDKDQKFS 1317
+GIE GAD YI+KPF+ L AR+ +++ ++ L++ + NE I N + K S
Sbjct: 1198 LKGIEGGADDYISKPFDKDFLKARVASILKSKNALQRYFYNE-------ITLNSNNTKIS 1250
Query: 1318 VKLNE-------VLNEHMTDTDFSVNDFAGIMGLGRTVFYKKVRGVTGYSPYEYLRVMRM 1370
+ E ++ EH+ D DF+++ +G+ R+ Y+K++ ++G S ++R +R+
Sbjct: 1251 AEYKEFLDHCIRIVEEHLIDPDFNIDTLTATIGMSRSNLYRKIKSISGQSANGFIRFIRL 1310
Query: 1371 KKAAEMLLTEDLTIAEVAYSVGINDPFYFSKCFKNQFGVSPSAYRKKLSEDENEPIN 1427
+KAAE+ + D TI E +Y VGINDP YF + F F ++PS Y KK + + IN
Sbjct: 1311 RKAAEIFINTDKTIQETSYMVGINDPKYFREQFYRLFNMNPSQYIKKFRKPFSNNIN 1367
Score = 112 bits (280), Expect = 3e-28
Identities = 159/646 (24%), Positives = 252/646 (39%), Gaps = 85/646 (13%)
Query: 11 LSFYLSSVHASV-EIRSNK--LTTG----------DGLANNSIRYMFQDSKGFMWMGTVN 57
L F+L H E+R+N + TG +GL + S +D +GF+W+GT N
Sbjct: 11 LHFFLLFTHVKAQELRTNNQPVLTGHYVIKTYGINEGLPSKSTTAALKDKRGFIWVGTEN 70
Query: 58 GLSYYDGNSFVSIYPDPNLPISLADPRIRNMEEDSNGFLWIATLSSLYSCYDLKHGRFVD 117
GL +DG +F SL + I + ED NG W+ T++ L + +D +F
Sbjct: 71 GLCKFDGYAFKIYVNITGDTTSLTNNYINAVVEDKNGVFWVGTMNGL-NKFDPVTEKFER 129
Query: 118 FTGCGEYKQSYSKKIIAS---DQSIWLW---------DNNNGCRRVVYQDGQFSSQAYKK 165
F + S S I S D++ LW N N VYQ A K
Sbjct: 130 FYHKENNRTSLSNNKIWSLLIDRTNKLWVGTDDGFNLFNKNSNAFTVYQPDFKDPDAIKG 189
Query: 166 ELGNLSSDKVLFVYESNDSPGHVWIGT-KQGLWKYHDGKLEAMD--TQGESWEHIFSYDQ 222
+ N ++ D G++W+G +GL K+ D K ++ TQ E D
Sbjct: 190 KSVNAIAE---------DKAGNLWLGNWSKGLNKF-DKKTKSFKNYTQKEVAGEKNPNDI 239
Query: 223 YTCIITGKKEIYRHSLSNNRLEKIASLTELGDTGVITGSLRLQHQWVMFTATGSYILDPV 282
+T + I+ S L + +E T G+ V+ T ++
Sbjct: 240 WTLCLDADGMIWIGSYWKGDLFRFDPKSESFTTYASKGTGNASIFSVLNLGTEKLLVGGS 299
Query: 283 TG------KLRRFSRLN----IKNGNVTRDNKGNAWVHNYTGNVWYVNTSTGDIKHFQFL 332
G KL ++ ++ NG + RD G W+ G + K F F+
Sbjct: 300 AGVFWVNTKLNKWEKIEELEFFANGGLYRDKSGMIWICGKNG---FSKIDFNQYK-FNFI 355
Query: 333 SSEHLGYIDVERYSIIHDSRDIIWITTYGNGLFAYDLNTGDLQHFTFEVSHSSHINSNYL 392
S L + E SII +D W+ T GLF Y+ + H ++ H+ + NS
Sbjct: 356 S---LPFGQAEIKSIISYGKD-FWVGT-NKGLFKYNPD----NHAVSKLQHTGNPNSLSS 406
Query: 393 QYIIE---DRSGGIWVSSEFSGLSHLEILNKGTLRIYPNGEDASDRSNTIRMLLRGKNGN 449
II D +WV E + E NK + + + + R L+
Sbjct: 407 SEIINLSTDLKNRLWVMGENGFDRYDEKANKFIHHHHRSALGSFFNEDVFRDLIEVNADE 466
Query: 450 VYMANRMG---------TLYEYDADLKNILRREKFTHNVYSMCEDNEGQLWLGMRGIGL- 499
Y+A G + Y D KN + +++Y + +D +G +W+G G GL
Sbjct: 467 YYLATDAGLKVYNDKTNSYTHYFNDPKN--QASLSNNHLYCLLKDAQGNVWIGTYGSGLS 524
Query: 500 ----RIGADQWYRYNSKDNNSLSNDNVYLIYRDRKGRMWIGTFGGGLNLAVKTGNGYQFK 555
+ Y N+ +SN+ V +Y D +W+ T GLN + N ++
Sbjct: 525 RFNPKTRKFSNYMINNSKRGGISNNIVNSLYLDSHQNVWVCT-RDGLNKYIAKTNTFEI- 582
Query: 556 HFFQDSYGEKRVRVIQEDRNGMMWVGTNNGIYIFHPDSLINSPKNY 601
+ Q+ + + ED NG +WV T GI +F P S KNY
Sbjct: 583 YSKQNGFASNVFTDLVEDNNGRLWVTTEQGISLFDPVS--KMVKNY 626
Score = 62.4 bits (150), Expect = 3e-13
Identities = 66/285 (23%), Positives = 118/285 (41%), Gaps = 18/285 (6%)
Query: 484 EDNEGQLWLGMRGIGLRIG--ADQWYRYNSKDNNSLSNDNVYLIYRDRKGRMWIGTFGGG 541
+D G +W+G + A + Y + D SL+N+ + + D+ G W+GT G
Sbjct: 58 KDKRGFIWVGTENGLCKFDGYAFKIYVNITGDTTSLTNNYINAVVEDKNGVFWVGTMNGL 117
Query: 542 LNLAVKTGNGYQFKHFFQD--SYGEKRVRVIQEDRNGMMWVGTNNGIYIFHPDSLINSPK 599
T +F H + S ++ + DR +WVGT++G +F+ +S N+
Sbjct: 118 NKFDPVTEKFERFYHKENNRTSLSNNKIWSLLIDRTNKLWVGTDDGFNLFNKNS--NAFT 175
Query: 600 NYVLYNHVNETFPSNEIRCLVNDHEGNMWIGTTGAGFAICYPGNDYQHLTFDCYSIKDGL 659
Y + + + D GN+W+G G D + +F Y+ K+
Sbjct: 176 VYQPDFKDPDAIKGKSVNAIAEDKAGNLWLGNWSKGL----NKFDKKTKSFKNYTQKEVA 231
Query: 660 ----PNGVIQSIVEDQDNKMWIATEYGISRFTLATKQIENYYFSSHTLGNVYSENTACIN 715
PN I ++ D D +WI + + F K ++S GN + +
Sbjct: 232 GEKNPND-IWTLCLDADGMIWIGSYWKGDLFRFDPKSESFTTYASKGTGNASIFSVLNLG 290
Query: 716 ADGRLLFGTNYGL--VVLDANKVENMEKLASTVFTGLHINGAHML 758
+ +LL G + G+ V NK E +E+L GL+ + + M+
Sbjct: 291 TE-KLLVGGSAGVFWVNTKLNKWEKIEELEFFANGGLYRDKSGMI 334
Score = 54.3 bits (129), Expect = 8e-11
Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 14/142 (9%)
Query: 600 NYVLYNH-VNETFPSNEIRCLVNDHEGNMWIGTTGAGFAIC----YPGNDYQHLTFDCYS 654
+YV+ + +NE PS + D G +W+GT +C Y Y ++T D S
Sbjct: 36 HYVIKTYGINEGLPSKSTTAALKDKRGFIWVGTENG---LCKFDGYAFKIYVNITGDTTS 92
Query: 655 IKDGLPNGVIQSIVEDQDNKMWIATEYGISRFTLATKQIENYYFSSHTLGNVYSEN--TA 712
L N I ++VED++ W+ T G+++F T++ E +Y + ++ + +
Sbjct: 93 ----LTNNYINAVVEDKNGVFWVGTMNGLNKFDPVTEKFERFYHKENNRTSLSNNKIWSL 148
Query: 713 CINADGRLLFGTNYGLVVLDAN 734
I+ +L GT+ G + + N
Sbjct: 149 LIDRTNKLWVGTDDGFNLFNKN 170