Pairwise Alignments
Query, 1450 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Subject, 1346 a.a., hypothetical protein from Pedobacter sp. GW460-11-11-14-LB5
Score = 511 bits (1317), Expect = e-148
Identities = 379/1395 (27%), Positives = 652/1395 (46%), Gaps = 202/1395 (14%)
Query: 173 KQNLKGDKIYTVFEDSEGDEWILTNKGISIIGKKQVDSDFPFQYIKEADGIIYLVSQSDK 232
++ L + + T+ +D EG W T G++ +
Sbjct: 27 EKGLSQNSVLTIIQDKEGFMWFGTQYGLN------------------------------R 56
Query: 233 LASYNFKTRQFKFIEIPYHVSMINEVKKFDSNTLLLATDNGLIIYKIKEKEFQLIDIRTS 292
Y FK + ++ + IN + L +AT NGL Y ++ F+ I I +S
Sbjct: 57 YDGYRFKIYRNTGLKNAISANEINYLFNDREQNLWVATSNGLNKYNPEKDAFEKIVINSS 116
Query: 293 TQ--PSNVVQSVYQDHYKELWI--FPQTTGVIRYNPSTKEM------------------- 329
S+V+ +Y+D LWI T +I+ P E+
Sbjct: 117 KNWPGSHVITCIYEDSKSNLWIGSINGLTKMIKNPPYKSELFLKSGLNGLASNEIKAISE 176
Query: 330 ----------QHLFTPADEVI------RYERKNK---------NVIFEDRQHTLWVLPPE 364
T D++ Y+ K I D+QH +WV
Sbjct: 177 DDSGKIWVGTTKGLTVIDKINGHYAFKTYQADGKPGSLADNYITTIVTDKQHRMWVGTQS 236
Query: 365 GNLSYYDRENKELKPMLKDSNNPKSVFSPLVRFYTLDNQGNCWLTSTRGIYKLSFFPHTY 424
G S + NK+ + +N + +R DN+GN W+ S G+ ++ P T
Sbjct: 237 GGFSTF---NKKTNAFVNYNNGKNGAVNDNIRKMIFDNKGNLWIGSLEGLMIMN--PSTG 291
Query: 425 NLVHIDNGFETRAFLCDNE---------KRLWVSSKAQMIRVYQPDGQL-----EGYLTP 470
+ I + E R L N +WV + + V P + G++ P
Sbjct: 292 KISSIKHDTENRKSLSQNSVYSLFMDKANAIWVGTYFGGVNVTYPTTTVFNNFQNGHINP 351
Query: 471 QGKISKDKQSFTSVYCFLEDHEG-NIWIGTKENGIYLLKKKSPDSYSVQQFTHQPNMPYS 529
S V LE++ G N+WIGT+ G+ +K S + + + N S
Sbjct: 352 AF-------SDNVVSSVLEENGGKNLWIGTEGGGLNFYEKSSNKN---TLYKNIQNNSSS 401
Query: 530 LSGNSVYSIFQDSHKRIWIGCYGGGINLLTYNKDGKTEFIHSDNELKNYPTGYASKVRHI 589
L N + + +D + +WIG +GGG+N L + F++S + + ++ +
Sbjct: 402 LGSNLIKVLLKDKDENLWIGTHGGGLNYLARGSNVFKRFLYSAED----QIATSREIPAL 457
Query: 590 SEAPGGVLLIGTTNGLL---------------TFSNQFERPEEIKFYRNCCES----GIS 630
+E G++ +GT NGL T S E+P IK N E G +
Sbjct: 458 AEDKKGIIWVGTQNGLYKSNELKNIFTRYNVKTASGIIEKPS-IKCLLNDAEDNLWMGTT 516
Query: 631 TSL----SGND------------------VMHTYTDKQKRTYIASFTGGISQIVSKNLLS 668
+ L G D + D +K+ +I S+ GG+ S+N
Sbjct: 517 SELYIKPKGQDRFAPVLQRIKNIRPKIKYINTIAQDSKKQIWIGSYYGGLYCYRSQN--- 573
Query: 669 NKIEFKTYTTDDGLASDLVQAMQEDQQGNLWILSENAISKFDAQRKTFENYGLNSLHQEF 728
N +E +T ++GL S+ +QA+ ED NLWI + N +S ++ + F+NY +
Sbjct: 574 NTLEI--FTEENGLPSNNIQAILEDDSHNLWISTSNGLSVYNPGTRHFKNYNTSDGLLNN 631
Query: 729 SFSEAAPVINARNQIVFGTDKGFIEISSKEMQKSSYVPPIVFTGLKVQGQSSVIAIDD-- 786
F++ A + + + FG G +Q ++ P+VFT LK+ +S I+ DD
Sbjct: 632 VFNKNARLKSVNGALYFGGYNGLTSFYPNNIQSNNVASPVVFTDLKLFNKS--ISADDES 689
Query: 787 ---------LEELRLTPSQRNVTFQFAALDYVDSKEIRYAYRLKGLEEEWHDGDKNRSAS 837
+L L Q +T +FA L+++ S + +AY+L G ++ W+ +A+
Sbjct: 690 GLLKADINFTNKLVLAYDQNTLTIEFALLNFIKSGKNHFAYKLDGYDKNWNTVSVP-AAT 748
Query: 838 YINLPNGKYKLQIKSTNSDGVWMDNIRTLSINVLPTFWETGWAWLLYVILFVLFTGSIVY 897
Y NLP+G Y +K N+DGV+ NI + I V P F+ T WA+L Y F + +V
Sbjct: 749 YTNLPSGSYTFLVKGINNDGVYSANIGRIEIVVNPPFYGTWWAYLFY---FCVAAAILVI 805
Query: 898 VLFYIYRLRHQVDIEQQLSNIKLRFFTDISHELRTPLTLISSPVNEVLENEDLSATAREH 957
++ Y+ +R + E++++ KL FFT+ISHE+RTPLTLI P+ +++E E +
Sbjct: 806 IIRYLL-IRAIFEKEKEINEHKLEFFTNISHEIRTPLTLIVGPLEDLIETEKDNPELYRS 864
Query: 958 LTVVQKNAERMLRLMNQILDFRKIQNQKMKVLVEKTDLIPLLEKVMINFRLIAEEKKINF 1017
L ++ NA+R++ L+ ++LDFRK ++ KM + V +++ ++ + F+ +A K+I +
Sbjct: 865 LQPIKNNADRLMNLVTELLDFRKAESGKMPLHVGSGNIVKFCREIFMAFQNMAISKQIEY 924
Query: 1018 RLASELKSIYAWIDRDKFEKIFFNLISNAFKYTPAEKAITIEVTKQTDKVTISVVDEGIG 1077
++ + I + D+ + EK+FFNL+SNAFK+TP E I ++ + VTI + D G G
Sbjct: 925 NFEADKEEIQLYFDKVQLEKVFFNLLSNAFKFTPKEGKINFKIEESDHLVTIKICDNGPG 984
Query: 1078 IEPTKLRTLFQRFETLAQQNMLQPSSGIGLSLVKEMVDMHHGTIKVTSEPEAGSR----- 1132
I + LF+RF + + +G+GLS K ++D+HHG I + P+
Sbjct: 985 IPLAEQENLFERFYQAKSASTI--GTGLGLSFSKSILDLHHGNITFENIPQNADASGLTC 1042
Query: 1133 FIVTLPLQKEVFEQDSQVEFILNDSQSPTTHPDSSLQTEKRAEAEDKEDMENNTAPD--T 1190
F V+L K F++ + + D H ++ E++ EN + +
Sbjct: 1043 FKVSLKTGKSHFKESDFITDAVYD------HDEARYGNFLTNAVENESAGENLVLAEEQS 1096
Query: 1191 LTILVVEDNEELKAFLKNILSENYTVITASNGKEGLQHAVDNIPDLIISDVMMPVMDGLE 1250
+L+VEDN+++++FLK L Y + + NG +GL+ A + IPD+IISDVMMPV+DGLE
Sbjct: 1097 YHVLLVEDNDDVRSFLKKSLQTKYHIHESENGLKGLEKAFEIIPDIIISDVMMPVLDGLE 1156
Query: 1251 MIRQIKENNNICHIPIIVLSAKASLDDRIAGLEQGIDDYITKPFSATYLKTRIASLLRQR 1310
+ R++K + HIPI++L+A+++ ++ GLE G D YI KPF+ L+ I +LL R
Sbjct: 1157 LCRRLKTDERTSHIPIVLLTARSAYVHQVNGLENGADSYIMKPFNLKILQLHIQNLLNAR 1216
Query: 1311 KSLQEIYMAKLTEGKEIAVAEALTPSQPQITPYDEQFMQKVMEFIEEQMDNAELTIDEFA 1370
+ +++ + A L P + ++ F+ K+++ IE +M + + + +
Sbjct: 1217 EKVKQ----------KFAGIIQLEPKNLLVNTTEQNFLHKIIQIIETKMTDPDFDVPMLS 1266
Query: 1371 EHLMLSRTIFYRKLKSIIGLTPVDFIREVRIKRAAQLIDSGEYNFSQVAYMTGFNDPKYF 1430
+ +S+ Y+K++++ L+ +FI+ +R+KRAAQL+ N S VAY G+ D KYF
Sbjct: 1267 SEIGMSQPTLYKKIRALTDLSVNEFIKSIRLKRAAQLLKQKIGNISDVAYAVGYTDRKYF 1326
Query: 1431 SKCFKKVVGITPSEY 1445
S FKK G +P+E+
Sbjct: 1327 SIEFKKYFGKSPTEF 1341
Score = 150 bits (380), Expect = 6e-40
Identities = 174/724 (24%), Positives = 303/724 (41%), Gaps = 90/724 (12%)
Query: 19 AQPTYQIKHYSVNDGMSQGIVQTIIQDKKGFLWFGTWNGLNKFDGYTFKNYK-TSYKDGY 77
AQ H++V G+SQ V TIIQDK+GF+WFGT GLN++DGY FK Y+ T K+
Sbjct: 15 AQQQIYFDHFNVEKGLSQNSVLTIIQDKEGFMWFGTQYGLNRYDGYRFKIYRNTGLKNA- 73
Query: 78 ILNTNRISQIAETKYGDIWCQAYDGRVYMFDNQTEKFIDILGSVAETMITNNYADHIYTL 137
++ N I+ + + ++W +G + ++ + + F I+ + ++ ++ IY
Sbjct: 74 -ISANEINYLFNDREQNLWVATSNG-LNKYNPEKDAFEKIVINSSKNWPGSHVITCIYED 131
Query: 138 SKGISWITFQNECAAIRIDDQLCKQGKGITLYSSFKQNLKGDKIYTVFEDSEGDEWILTN 197
SK WI N + + K S L ++I + ED G W+ T
Sbjct: 132 SKSNLWIGSINGLTKMIKNPPY----KSELFLKSGLNGLASNEIKAISEDDSGKIWVGTT 187
Query: 198 KGISIIGKKQVDSDFPFQYIKEADG-------------------IIYLVSQSDKLASYNF 238
KG+++I K ++ + F+ +ADG +++ +QS +++N
Sbjct: 188 KGLTVIDK--INGHYAFK-TYQADGKPGSLADNYITTIVTDKQHRMWVGTQSGGFSTFNK 244
Query: 239 KTRQFKFIEIPYHVSMINEVKK--FDS-NTLLLATDNGLIIYKIKEKEFQLIDIRTSTQP 295
KT F + ++ + ++K FD+ L + + GL+I + I T +
Sbjct: 245 KTNAFVNYNNGKNGAVNDNIRKMIFDNKGNLWIGSLEGLMIMNPSTGKISSIKHDTENRK 304
Query: 296 S---NVVQSVYQDHYKELWIFPQTTGVIRYNPSTKEMQHLFTPADEVIRYERKNKNVIFE 352
S N V S++ D +W+ GV P+T + + +V+ E
Sbjct: 305 SLSQNSVYSLFMDKANAIWVGTYFGGVNVTYPTTTVFNNFQNGHINPAFSDNVVSSVLEE 364
Query: 353 DRQHTLWVLPPEGNLSYYDRENKELKPMLKDSNNPKSVFSPLVRFYTLDNQGNCWLTSTR 412
+ LW+ G L++Y++ + + NN S+ S L++ D N W+ +
Sbjct: 365 NGGKNLWIGTEGGGLNFYEKSSNKNTLYKNIQNNSSSLGSNLIKVLLKDKDENLWIGTHG 424
Query: 413 GIYKLSFFPHTYNLV---------HIDNGFETRAFLCDNEKRLWVSSKAQMIRVYQPDGQ 463
G L++ N+ I E A D + +WV ++ + + +
Sbjct: 425 G--GLNYLARGSNVFKRFLYSAEDQIATSREIPALAEDKKGIIWVGTQNGLYKSNELKNI 482
Query: 464 LEGY--LTPQGKISKDKQSFTSVYCFLEDHEGNIWIGTKENGIYLLKKKSPDSYS--VQQ 519
Y T G I K S+ C L D E N+W+GT +K K D ++ +Q+
Sbjct: 483 FTRYNVKTASGIIEK-----PSIKCLLNDAEDNLWMGTTSE--LYIKPKGQDRFAPVLQR 535
Query: 520 FTH-QPNMPYSLSGNSVYSIFQDSHKRIWIGCYGGGINLLTYNKDGKT-EFIHSDNELKN 577
+ +P + Y + +I QDS K+IWIG Y GG L Y T E +N L
Sbjct: 536 IKNIRPKIKY------INTIAQDSKKQIWIGSYYGG--LYCYRSQNNTLEIFTEENGLP- 586
Query: 578 YPTGYASKVRHISEAPGGVLLIGTTNGLLTFSNQFERPEEIKFYRNCCESGISTSLSGND 637
++ ++ I E L I T+NGL ++ P F G+ ++ +
Sbjct: 587 -----SNNIQAILEDDSHNLWISTSNGLSVYN-----PGTRHFKNYNTSDGLLNNVFNKN 636
Query: 638 VMHTYTDKQKRTYIASFTGGISQIVS---KNLLSNKIEFKTYTTDDGLASDLVQAMQEDQ 694
+ K A + GG + + S N+ SN + TD L + + A +D+
Sbjct: 637 A------RLKSVNGALYFGGYNGLTSFYPNNIQSNNVASPVVFTDLKLFNKSISA--DDE 688
Query: 695 QGNL 698
G L
Sbjct: 689 SGLL 692
Score = 34.7 bits (78), Expect = 7e-05
Identities = 34/159 (21%), Positives = 71/159 (44%), Gaps = 17/159 (10%)
Query: 670 KIEFKTYTTDDGLASDLVQAMQEDQQGNLWILSENAISKFDAQRKTFENYGLNSLHQEFS 729
+I F + + GL+ + V + +D++G +W ++ ++++D R F+ Y L S
Sbjct: 18 QIYFDHFNVEKGLSQNSVLTIIQDKEGFMWFGTQYGLNRYDGYR--FKIYRNTGLKNAIS 75
Query: 730 FSEAAPVINARNQIVF-GTDKGF------------IEISSKEMQKSSYVPPIVFTGLKVQ 776
+E + N R Q ++ T G I I+S + S+V ++ K
Sbjct: 76 ANEINYLFNDREQNLWVATSNGLNKYNPEKDAFEKIVINSSKNWPGSHVITCIYEDSK-- 133
Query: 777 GQSSVIAIDDLEELRLTPSQRNVTFQFAALDYVDSKEIR 815
+ +I+ L ++ P ++ F + L+ + S EI+
Sbjct: 134 SNLWIGSINGLTKMIKNPPYKSELFLKSGLNGLASNEIK 172