Pairwise Alignments
Query, 1450 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Subject, 1347 a.a., hypothetical protein from Pedobacter sp. GW460-11-11-14-LB5
Score = 434 bits (1117), Expect = e-125
Identities = 387/1405 (27%), Positives = 643/1405 (45%), Gaps = 195/1405 (13%)
Query: 150 CAAIRIDDQLCKQGKGITLYSSFKQNLKGDKIYTVFEDSEGDEWILTNKGISIIGKKQVD 209
C A++++ QL ++ + S + L + + ++ +D +G W T G+S
Sbjct: 29 CGALQVNAQL-----SVSTHFSTEDGLVQNNVLSIAQDRQGFMWFGTENGLS-------- 75
Query: 210 SDFPFQYIKEADGIIYLVSQSDKLASYNFKTRQFKFI----EIPYHVSMINEVKKFDSNT 265
DG+ + R FK I P ++I + N
Sbjct: 76 ---------RFDGL---------------RWRSFKNILGDTNKPSSPALIRSLFWDQQNR 111
Query: 266 LLLATDNGLIIYKIKEKEFQLIDIRTSTQPSNVVQSVYQDHYKELWIFPQTTGVIRYNPS 325
L + T GLI + ++F+ I + QP V+ V +D + + T G++
Sbjct: 112 LWMGTALGLITFDPLTEKFRQIKLPYPIQPE--VKQVTRDLSGNI-LAGTTAGIVLITKE 168
Query: 326 TKEMQ--HLFTPADEVIRYERKNKNVIFEDRQHTLWVLPPEGNLSYYDRENKELKPMLKD 383
K + F ++++ + IF +W N ++ + K + ML
Sbjct: 169 NKIIASARAFDDGEDILCH------TIFCGSDGRIWC---GTNRGLFEVKIKADRIMLSR 219
Query: 384 SNNPKSVF--SPLVRFYTLDNQGNCWLTSTRG-----IYKLSFFPHTYNLVHIDNGFETR 436
+ VF + +DN G W S G Y+ F + G
Sbjct: 220 TTAELPVFLQKEKITSIKMDNNGRFWFGSYAGGLLLCHYQQGKFIEAQQQPALPGG---- 275
Query: 437 AFLCDNEKRLWVSSKAQMIRVYQPDGQLE---GYLTPQGKISK--DKQSF--TSVYCFLE 489
++ R +S I V DG L SK D+QS +S++ +
Sbjct: 276 ---ATHKIRSIISLLDHKISVATADGLFFFDINNLNTFELTSKAGDEQSLHNSSIHSLFQ 332
Query: 490 DHEGNIWIGTKENGIYLLKKKSPDSYSVQQFTHQPNMPYSLSGNS--VYSIFQDSHKRIW 547
G IWIG+ +G+ L+K + F H P +L+ N V S+ + +W
Sbjct: 333 QRSGTIWIGSYYSGLDLIKPP------LAPFRHLGIGPTALNLNHRVVSSVCNRNQTELW 386
Query: 548 IGCYGGGINLLTYNKDGKTEFIHSDNELKNYPTGYASKVRHISEAPGGVLLIGTTNGLL- 606
IG GGGIN+ YN+ K + + N+ N + ++ ++ + + G L IGT +G L
Sbjct: 387 IGTEGGGINI--YNQSTK-QVSYLKNQQGNDKSISSNFIKTLFKDEDGNLWIGTFSGTLD 443
Query: 607 -------TFSNQFERPEEIKFYRNCCESGIS-----------------TSLSGNDVMH-- 640
T ++ E I + E G++ T L + +M
Sbjct: 444 VLNASTNTIEHRLTGTERITEVNSIVEDGLNRLWITSSNGLKVYKRIRTHLKADRLMQQP 503
Query: 641 ---------TYTDKQKRTYIASFT-------------------GGISQ--------IVSK 664
+ D +KR + A+ T IS+ + S+
Sbjct: 504 GLKSFLAGVAFQDTKKRLWFATETKVMKVEGDSIRIYHLKYPVNTISEHHGTIYLGLESR 563
Query: 665 NLLS---NKIEFKTYTTDDGLASDLVQAMQEDQQGNLWILSENAISKFDAQRKTFENYGL 721
L + + +F Y + + + V ++ D+Q +W+ S++ + K ++K Y
Sbjct: 564 GLAAFNEQRGQFALYQINSQVNNRSVYSIAFDRQNRIWLASDSGLLKVSPKQKIVTQYTK 623
Query: 722 NSLHQEFSFSEAAPVINAR----NQIVFGTDKGFIEISSKEMQKSSYVPPIVFTGLK--- 774
+F+ INAR N + FGT G I +++ + IV TG++
Sbjct: 624 ADGLISTNFN-----INARYERDNNLFFGTLDGLIYFDPDQIRDDTTKSSIVITGMRIFD 678
Query: 775 --VQGQSSVI--AIDDLEELRLTPSQRNVTFQFAALDYVDSKEIRYAYRLKGLEEEWHDG 830
V+ SSV+ +I + L+ +Q ++TF+FA LD++ K+ + Y L+GL + W
Sbjct: 679 VPVEIDSSVLRKSITYTNRVELSHNQNSLTFEFALLDFIKPKKNAFRYSLQGLSKGWTTT 738
Query: 831 DKNRSASYINLPNGKYKLQIKSTNSDGVWMDNIRTLSINVLPTFWETGWAWLLYVILFVL 890
+ A++ NL G Y L + N WM+ IR L+IN+ P FW T WA++LY I+
Sbjct: 739 NL-AEATFNNLAPGTYTLMVSGNNGSPNWMEPIR-LTINIHPPFWATWWAYMLYGIILT- 795
Query: 891 FTGSIVYVLFYIYRLRHQVDIEQQLSNIKLRFFTDISHELRTPLTLISSPVNEVLENEDL 950
SIV+ + + LR + E +L K+ FFT++SHE+RT L+LIS P+ +++ +E L
Sbjct: 796 ---SIVFFISRYFVLRTLLKREDELHQYKINFFTNVSHEIRTHLSLISPPIEQLVSDEQL 852
Query: 951 SATAREHLTVVQKNAERMLRLMNQILDFRKIQNQKMKVLVEKTDLIPLLEKVMINFRLIA 1010
++ + V NA R+L L+N++LDFRK +++ + + DL+P+LE + F A
Sbjct: 853 GKKQKDKILGVAGNARRLLTLVNELLDFRKTEDKHLTLSENVQDLLPILEDCLQMFSETA 912
Query: 1011 EEKKINFRLASE-LKSIYAWIDRDKFEKIFFNLISNAFKYTPAEKAITIEVTKQTDKVTI 1069
E+K+I L E LKS + D + +K NL++NA+K+T + + +++ +VTI
Sbjct: 913 EQKQITTLLEKENLKSAFLLCDAFQLKKAIINLLANAYKFTQNGGLVKLRISQTYHEVTI 972
Query: 1070 SVVDEGIGIEPTKLRTLFQRFETLAQQNMLQPSSGIGLSLVKEMVDMHHGTIKVTSEPEA 1129
++ D G GI + L LF+ + +A GIGL+L K +V++H GTI VTS E
Sbjct: 973 TIEDNGRGISQSHLNKLFENYYQVADHGFQNTGYGIGLALSKAIVELHQGTITVTSRLET 1032
Query: 1130 GSR-----FIVTLPL-QKEVFEQDSQVEFILNDSQSPTTHPDSSLQTEKRAEAEDKEDME 1183
+ F ++LP QKE ++ L + T PD + + +
Sbjct: 1033 MNEPGHTSFTISLPKRQKEAYDS-------LAAYNAEHTFPDHGDEQTQHKPLLPLTQAD 1085
Query: 1184 NNTAPDTLTILVVEDNEELKAFLKNILSENYTVITASNGKEGLQHAVDNIPDLIISDVMM 1243
+ P TIL+ EDN EL L +IL+ Y VI + NGKE + A +IPDLIISDVMM
Sbjct: 1086 ESQKP---TILLAEDNLELATLLDDILNPYYHVIISRNGKEAWEQAKRHIPDLIISDVMM 1142
Query: 1244 PVMDGLEMIRQIKENNNICHIPIIVLSAKASLDDRIAGLEQGIDDYITKPFSATYLKTRI 1303
P M G + IK N HIP I+L+AK +D I GL G D Y+TKPF+ L ++
Sbjct: 1143 PEMSGFDFCDLIKSNVATNHIPFILLTAKTQTEDVITGLSHGADVYLTKPFTPQALLLQV 1202
Query: 1304 ASLLRQRKSLQEIYMAKLTEGKE-IAVAEALTPSQPQITPYDEQFMQKVMEFIEEQMDNA 1362
+L+ +++ L + E I + L Q Q+ ++FM +++E I ++N
Sbjct: 1203 NNLIVAIQNVHTHVGQLLNKNSEPIDIFNQLI--QTQLGTESKKFMNQLVENITASIENP 1260
Query: 1363 ELTIDEFAEHLMLSRTIFYRKLKSIIGLTPVDFIREVRIKRAAQLIDSGEYNFSQVAYMT 1422
E ++E A + +S I Y+K+KS+ G + DFI+ +R+K+AA+L+++ Y QV+YM
Sbjct: 1261 EFGVNELARLMNMSTPILYKKVKSVTGSSVNDFIKGLRLKKAAELLETRLYTVYQVSYMV 1320
Query: 1423 GFNDPKYFSKCFKKVVGITPSEYKE 1447
GF D +YFSK FKK G PSE+ E
Sbjct: 1321 GFLDSRYFSKEFKKFFGKLPSEWIE 1345
Score = 111 bits (278), Expect = 4e-28
Identities = 143/661 (21%), Positives = 263/661 (39%), Gaps = 110/661 (16%)
Query: 27 HYSVNDGMSQGIVQTIIQDKKGFLWFGTWNGLNKFDGYTFKNYKTSYKDGYILNTNR--- 83
H+S DG+ Q V +I QD++GF+WFGT NGL++FDG ++++K D TN+
Sbjct: 43 HFSTEDGLVQNNVLSIAQDRQGFMWFGTENGLSRFDGLRWRSFKNILGD-----TNKPSS 97
Query: 84 ---ISQIAETKYGDIWCQAYDGRVYMFDNQTEKFIDILGSVAETMITNNYADHIYTLSKG 140
I + + +W G + FD TEKF I + + +++
Sbjct: 98 PALIRSLFWDQQNRLWMGTALGLI-TFDPLTEKFRQI-------KLPYPIQPEVKQVTRD 149
Query: 141 ISWITFQNECAAIRIDDQLCKQGKGITLYSSFKQNLKGDKI--YTVFEDSEGDEWILTNK 198
+S A I + + K+ K I +F G+ I +T+F S+G W TN+
Sbjct: 150 LSGNILAGTTAGIVL---ITKENKIIASARAFDD---GEDILCHTIFCGSDGRIWCGTNR 203
Query: 199 GISIIGKK-------QVDSDFPFQYIKEA--------DGIIYLVSQSDKLASYNFKTRQF 243
G+ + K + ++ P KE +G + S + L ++ +Q
Sbjct: 204 GLFEVKIKADRIMLSRTTAELPVFLQKEKITSIKMDNNGRFWFGSYAGGLLLCHY--QQG 261
Query: 244 KFIEIPYHVSM-------INEVKKFDSNTLLLATDNGLIIYKIKE-KEFQLIDIRTSTQP 295
KFIE ++ I + + + +AT +GL + I F+L Q
Sbjct: 262 KFIEAQQQPALPGGATHKIRSIISLLDHKISVATADGLFFFDINNLNTFELTSKAGDEQS 321
Query: 296 --SNVVQSVYQDHYKELWIFPQTTGVIRYNPSTKEMQHLFTPADEVIRYERKNKNVIFED 353
++ + S++Q +WI +G+ P +HL + + + +
Sbjct: 322 LHNSSIHSLFQQRSGTIWIGSYYSGLDLIKPPLAPFRHLGI-GPTALNLNHRVVSSVCNR 380
Query: 354 RQHTLWVLPPEGNLSYYDRENKELKPMLKDSNNPKSVFSPLVRFYTLDNQGNCWL---TS 410
Q LW+ G ++ Y++ K++ + N KS+ S ++ D GN W+ +
Sbjct: 381 NQTELWIGTEGGGINIYNQSTKQVSYLKNQQGNDKSISSNFIKTLFKDEDGNLWIGTFSG 440
Query: 411 TRGIYKLSFFPHTYNLVHIDNGFETRAFLCDNEKRLWVSSKAQMIRVY------------ 458
T + S + L + E + + D RLW++S + ++VY
Sbjct: 441 TLDVLNASTNTIEHRLTGTERITEVNSIVEDGLNRLWITS-SNGLKVYKRIRTHLKADRL 499
Query: 459 --QP------------DGQLEGYLTPQGKISKDKQSFTSVYCF------LEDHEGNIWIG 498
QP D + + + K+ K + +Y + +H G I++G
Sbjct: 500 MQQPGLKSFLAGVAFQDTKKRLWFATETKVMKVEGDSIRIYHLKYPVNTISEHHGTIYLG 559
Query: 499 TKENGIYLLKKKSPDSYSVQQFTHQPNMPYSLSGNSVYSIFQDSHKRIWIGCYGGGINLL 558
+ G+ ++ +++ Q Q N SVYSI D RIW+ G + +
Sbjct: 560 LESRGLAAFNEQR-GQFALYQINSQVN------NRSVYSIAFDRQNRIWLASDSGLLKVS 612
Query: 559 TYNKDGKTEFIHSDNELKNYPTGYASKVRHISEAPGGVLLIGTTNGLLTFSNQFERPEEI 618
K T++ +D + T + R+ + L GT +GL+ F P++I
Sbjct: 613 PKQKI-VTQYTKADGLIS---TNFNINARYERD---NNLFFGTLDGLIYFD-----PDQI 660
Query: 619 K 619
+
Sbjct: 661 R 661
Score = 38.5 bits (88), Expect = 5e-06
Identities = 54/264 (20%), Positives = 98/264 (37%), Gaps = 60/264 (22%)
Query: 25 IKHYSVND-GMSQGIVQTIIQDKKGFLWFGTWNGLNKFDGYTFKNYKTSYKDGYILNTNR 83
+K+ ND +S ++T+ +D+ G LW GT++G N T+ + + T R
Sbjct: 407 LKNQQGNDKSISSNFIKTLFKDEDGNLWIGTFSGT-----LDVLNASTNTIEHRLTGTER 461
Query: 84 ISQIAETKYGDIWCQAYDGRVYMFDNQTEKFIDILGSVAETMITNNYADHIYTLSKGISW 143
I+++ S+ E + W
Sbjct: 462 ITEV-------------------------------NSIVEDGLNR-------------LW 477
Query: 144 ITFQNECAAIRIDDQLCKQGKGITLYSSFKQNLKGDKIYTVFEDSEGDEWILTNKGISII 203
IT N +++ ++ K L + LK F+D++ W T + +
Sbjct: 478 ITSSN---GLKVYKRIRTHLKADRLMQ--QPGLKSFLAGVAFQDTKKRLWFATETKVMKV 532
Query: 204 GKKQV---DSDFPFQYIKEADGIIYLVSQSDKLASYNFKTRQFKFIEIPYHVS--MINEV 258
+ +P I E G IYL +S LA++N + QF +I V+ + +
Sbjct: 533 EGDSIRIYHLKYPVNTISEHHGTIYLGLESRGLAAFNEQRGQFALYQINSQVNNRSVYSI 592
Query: 259 KKFDSNTLLLATDNGLIIYKIKEK 282
N + LA+D+GL+ K+K
Sbjct: 593 AFDRQNRIWLASDSGLLKVSPKQK 616