Pairwise Alignments
Query, 1450 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Subject, 1368 a.a., hybrid sensor histidine kinase/response regulator from Pedobacter sp. GW460-11-11-14-LB5
Score = 501 bits (1289), Expect = e-145
Identities = 356/1373 (25%), Positives = 639/1373 (46%), Gaps = 160/1373 (11%)
Query: 171 SFKQNLKGDKIYTVFEDSEGDEWILTNKGISIIGKK-------------QVDSDFPFQYI 217
S ++ L ++ + +D+ G WI T G++ K V S +
Sbjct: 49 SVEKGLSQSTVFAIKQDTLGFIWIGTQDGLNRYDSKGFKVYRPVKSDPKSVQSYYTRTLF 108
Query: 218 KEADGIIYLVSQSDKLASYNFKTRQFKFIEIP-----YHVSMINEVKKFDSNTLLLATDN 272
+ G ++ V + ++ YN+ T F ++P ++VS I E D + AT
Sbjct: 109 IDHTGSLW-VGGNQGVSRYNYATDSFTNYKLPRSLGEWYVSSITE----DPQHNIWATSV 163
Query: 273 GLIIYKIKEKEFQLIDIRTSTQPSNVVQSVYQDHYKELWIFPQTTGVIRYNPSTKEMQHL 332
++K+ E Q + + + + + VY +K+ + G+ + ++ +
Sbjct: 164 VGGVFKLTAGESQFKQVNYDSFNTGIKRVVYVGSWKQNILIGTEVGLFKMTGPKNKLVKI 223
Query: 333 FTPADEVIRYERKNKNVIFEDRQHTLWVLPPEGNLSYYDRENKELKPMLKDSNNPKSVFS 392
D + N ++ D WV L Y E E K + S KS+
Sbjct: 224 DLGTD------KPAINDVYIDGD-VFWVATEGDGLIQYHFETGE-KKVFMHSPGGKSIAD 275
Query: 393 PLVRFYTLDNQGNCWLTSTRGIY-------KLSFFPHTYNLVHIDNGFETRAFLCDNEKR 445
+R D GN WL + +G+ L + H + + + R F D +
Sbjct: 276 NNIRCVGKDTDGNIWLGTFKGLTIFDLNTNTLENYYHQISQPYTISQNSVRCFFKDKQNG 335
Query: 446 LWVSSKAQMIRVYQPDGQLEGYLTPQ-GKISKDKQSFTSVYCFLEDHEGNIWIGTKENGI 504
+W+ + I Y + L+ G++S + + +++ ED +GN WIGT + G+
Sbjct: 336 IWLGTFYGGINYYHKNDIKFNLLSQNTGRLSLNDEVVSAIK---EDSKGNFWIGTNDKGL 392
Query: 505 YLLKKKSPDSYSVQQFTHQPNMPYSLSGNSVYSIFQDSHKRIWIGCYGGGINLLTYNKDG 564
+ + + + F++ N SLS N++ +I D+ + + +G + GG+N+L N
Sbjct: 393 NYWNRATNN---ISYFSNNENNANSLSANNIKAIAFDNDQNLLVGMHNGGLNILNPNTGN 449
Query: 565 KTEFIHSDNELKNYPTGYASKVRH-ISEAPGGVLLIGTTNGLLTFSNQFERPEEIKFYRN 623
+ HS+N+ P A + + I + + IGT +GL F+ Q + I +
Sbjct: 450 VKRYRHSEND----PNSIAGDLVYGILKDYKNRIWIGTRSGLDQFNPQSQTFTHIHLDK- 504
Query: 624 CCESGISTSLSGNDVMHTYTDKQKRTYIASFTGGISQIVSKNLL---------------- 667
S +D+ + + D + R +I + T G++ N+L
Sbjct: 505 -----AGKRPSSDDITYLFEDSKHRIWIGT-TNGVTLFYPDNMLFGNDLNNQLRDDVISC 558
Query: 668 ---------------------SNKIEFKTYTTDDGLASDLVQAMQEDQQGNLWILSENAI 706
N+ F TY + +Q D +GN+W+ + +
Sbjct: 559 ITEDKKGRIWIGSREGLILYDENQQSFVTYKNRKDFIKGTIYGLQPDNEGNIWVSTNRGL 618
Query: 707 SKFDAQRKTFENYGLNSLHQEFSFSEAAPVINARNQIVFGTDKGFIEISSKEMQKSSYVP 766
+++ + KT + + Q F++ A + ++FG KG +++
Sbjct: 619 IRYNPEAKTSQAFDETDGLQNNQFNDYAFCKASDGMLLFGGIKGLSYFYPSSIKQQPLPL 678
Query: 767 PIVFTGLKVQGQSSVIA---------IDDLEELRLTPSQRNVTFQFAALDYVDSKEIRYA 817
+ FTGL+V S ID +L + T F +Y+ + +Y
Sbjct: 679 KLTFTGLEVFNNSVTSGDETKILENHIDQSTQLEFAAEYKQFTIHFNTFNYISANRTKYL 738
Query: 818 YRLKGLEEEWHDGDKNRSASYINLPNGKYKLQIKSTNSDGVWMDNIRTLSINVLPTFWET 877
Y+L G +++W + + +Y NL G Y IK+ +G +RTL I + P ++
Sbjct: 739 YKLDGFDKDWQHTE-DLKITYNNLRAGSYNFLIKAVGPNGE-ASAVRTLKIIISPPWYNA 796
Query: 878 GWAWLLYVILFVLFTGSIVYVLFYIYRLR----HQVDIEQ-------QLSNIKLRFFTDI 926
W Y+ +F+ G+ Y+ + I R HQ+ +E+ ++ +K+ FFT++
Sbjct: 797 TW---FYLFVFIDLVGAS-YIAYRIIDQRIKALHQLKLERIDKEKVRYINQVKMDFFTNV 852
Query: 927 SHELRTPLTLISSPVNEVLENEDLSATAREHLTVVQKNAERMLRLMNQILDFRKIQNQKM 986
SHELRTPLTLI +P+ E+++ + ++ NA+R+ L++Q+ +FRK +
Sbjct: 853 SHELRTPLTLILAPLEELIKKPSTDKVITKRHEMMLINAKRLYNLVDQLFEFRKTETGTR 912
Query: 987 KVLVEKTDLIPLLEKVMINFRLIAEEKKINFRLASELKSIYAWIDRDKFEKIFFNLISNA 1046
K+ V K+D++ + +V +F+ ++++ ++ + S + + D D EKI FNL+SNA
Sbjct: 913 KLKVSKSDIVSFIHEVYESFKPLSDKNQVQYTYHSSEAKLSFYFDNDAMEKILFNLLSNA 972
Query: 1047 FKYTPAEKAITIEVTKQTDKVTISVVDEGIGIEPTKLRTLFQRFETLAQQNMLQPSSGIG 1106
FKYT A I++E++ Q + I+V D G+GI + +F RF + Q M SG+G
Sbjct: 973 FKYTGAHNKISVELSTQDNFAIITVTDTGVGISEDDIAKVFDRFYQVNNQEM-NLGSGVG 1031
Query: 1107 LSLVKEMVDMHHGTIKVTSEPEAGSRFIVTLPLQKEVFEQDSQVEFILNDSQSPTTHPDS 1166
L+ K ++++HHG+IK SE GS+F V++P+ V+++D + E
Sbjct: 1032 LAFTKRLIELHHGSIKAESELGRGSKFTVSIPMADAVYQEDVKTE--------------- 1076
Query: 1167 SLQTEKRAEAEDKEDMENNT--APDTLTI------------LVVEDNEELKAFLKNILSE 1212
+++ E E++ ENN A +LTI L+V+DN+E+ +L++ E
Sbjct: 1077 NMRYELSIVPEEEAIAENNLMYADQSLTIGLNENDGQRSKLLLVDDNKEILDYLQDYFKE 1136
Query: 1213 NYTVITASNGKEGLQHAVDNIPDLIISDVMMPVMDGLEMIRQIKENNNICHIPIIVLSAK 1272
+Y + A +GK L + DLI+SDVMMP +DGL +++K+N N HIP+I+L+AK
Sbjct: 1137 SYEITIAFDGKMALDILENEQFDLIVSDVMMPELDGLHFCKRLKQNINTSHIPVILLTAK 1196
Query: 1273 ASLDDRIAGLEQGIDDYITKPFSATYLKTRIASLLRQRKSLQEIYMAKLTEGKEIAVAEA 1332
++ +I GLE G DDYITKPFS L +IASLL+ RK L+E Y ++
Sbjct: 1197 TEVNQQIKGLEMGADDYITKPFSVEMLGAKIASLLKSRKRLKEYY----------GGSKE 1246
Query: 1333 LTPSQPQITPYDEQFMQKVMEFIEEQMDNAELTIDEFAEHLMLSRTIFYRKLKSIIGLTP 1392
+ P DE+F+++ + +E+ + +++ ++D+F+ + +SR+ Y K K+I G +
Sbjct: 1247 VVPQNLAFNTLDEEFLKEAIAIVEKYLADSDFSVDKFSREIGMSRSNLYLKFKAITGESA 1306
Query: 1393 VDFIREVRIKRAAQLIDSGEYNFSQVAYMTGFNDPKYFSKCFKKVVGITPSEY 1445
DFI+ +R +A +L+ S Y +Q+ YM GFN P YFS FK+ G PSEY
Sbjct: 1307 TDFIKRIRFSKAVELMQSKRYTIAQITYMCGFNSPSYFSTAFKQYYGCMPSEY 1359
Score = 112 bits (280), Expect = 3e-28
Identities = 167/711 (23%), Positives = 278/711 (39%), Gaps = 103/711 (14%)
Query: 5 RLLLISLFNYCI---LVAQPTYQ-IKHYSVNDGMSQGIVQTIIQDKKGFLWFGTWNGLNK 60
R LL ++ C+ L AQ + ++ SV G+SQ V I QD GF+W GT +GLN+
Sbjct: 21 RYLLTAILVLCVFSKLHAQINGRHFRNISVEKGLSQSTVFAIKQDTLGFIWIGTQDGLNR 80
Query: 61 FDGYTFKNYKTSYKDGYILNTNRISQIAETKYGDIWCQAYDGRVYMFDNQTEKFIDI--- 117
+D FK Y+ D + + + G +W G V ++ T+ F +
Sbjct: 81 YDSKGFKVYRPVKSDPKSVQSYYTRTLFIDHTGSLWVGGNQG-VSRYNYATDSFTNYKLP 139
Query: 118 --LGSVAETMITNNYADHIYTLS--KGISWITFQNECAAIRIDDQLCKQG-KGITLYSSF 172
LG + IT + +I+ S G+ +T E +++ G K + S+
Sbjct: 140 RSLGEWYVSSITEDPQHNIWATSVVGGVFKLT-AGESQFKQVNYDSFNTGIKRVVYVGSW 198
Query: 173 KQN-----------LKGDKIYTVFED------------SEGDEWILTNKGISII------ 203
KQN + G K V D +GD + + +G +I
Sbjct: 199 KQNILIGTEVGLFKMTGPKNKLVKIDLGTDKPAINDVYIDGDVFWVATEGDGLIQYHFET 258
Query: 204 GKKQVDSDFPFQYI----------KEADGIIYL-VSQSDKLASYNFKTRQFKFIEI--PY 250
G+K+V P K+ DG I+L + + N T + + +I PY
Sbjct: 259 GEKKVFMHSPGGKSIADNNIRCVGKDTDGNIWLGTFKGLTIFDLNTNTLENYYHQISQPY 318
Query: 251 HVSMINEVKKF---DSNTLLLATDNGLIIYKIK-EKEFQLIDIRTSTQPSN--VVQSVYQ 304
+S N V+ F N + L T G I Y K + +F L+ T N VV ++ +
Sbjct: 319 TISQ-NSVRCFFKDKQNGIWLGTFYGGINYYHKNDIKFNLLSQNTGRLSLNDEVVSAIKE 377
Query: 305 DHYKELWIFPQTTGVIRYNPSTKEMQHLFTPADEVIRYERKNKNVIFEDRQHTLWVLPPE 364
D WI G+ +N +T + + + N I D L V
Sbjct: 378 DSKGNFWIGTNDKGLNYWNRATNNISYFSNNENNANSLSANNIKAIAFDNDQNLLVGMHN 437
Query: 365 GNLSYYDRENKELKPMLKDSNNPKSVFSPLVRFYTLDNQGNCWLTSTRGIYKLSFFPHTY 424
G L+ + +K N+P S+ LV D + W+ + G+ + + T+
Sbjct: 438 GGLNILNPNTGNVKRYRHSENDPNSIAGDLVYGILKDYKNRIWIGTRSGLDQFNPQSQTF 497
Query: 425 NLVHID------NGFETRAFLCDNEKRLWVSSKAQMIRVYQPDGQLEGYLTPQGKISKDK 478
+H+D + + D++ R+W+ + + ++ PD L G ++
Sbjct: 498 THIHLDKAGKRPSSDDITYLFEDSKHRIWIGT-TNGVTLFYPDNML------FGNDLNNQ 550
Query: 479 QSFTSVYCFLEDHEGNIWIGTKENGIYLLKKKSPDSYSVQQFTHQPNMPYSLSGNSVYSI 538
+ C ED +G IWIG++E G+ L + Q F N + G ++Y +
Sbjct: 551 LRDDVISCITEDKKGRIWIGSRE-GLILYDENQ------QSFVTYKNRKDFIKG-TIYGL 602
Query: 539 FQDSHKRIWIGCYGGGINLLTYNKDGKTE--FIHSDNELKNYPTGYASKVRHISEAPGGV 596
D+ IW+ G L+ YN + KT F +D N YA +A G+
Sbjct: 603 QPDNEGNIWVSTNRG---LIRYNPEAKTSQAFDETDGLQNNQFNDYA-----FCKASDGM 654
Query: 597 LLIGTTNGLLTF--SNQFERPEEIKF-------YRNCCESGISTSLSGNDV 638
LL G GL F S+ ++P +K + N SG T + N +
Sbjct: 655 LLFGGIKGLSYFYPSSIKQQPLPLKLTFTGLEVFNNSVTSGDETKILENHI 705
Score = 30.8 bits (68), Expect = 0.001
Identities = 11/44 (25%), Positives = 28/44 (63%)
Query: 669 NKIEFKTYTTDDGLASDLVQAMQEDQQGNLWILSENAISKFDAQ 712
N F+ + + GL+ V A+++D G +WI +++ ++++D++
Sbjct: 41 NGRHFRNISVEKGLSQSTVFAIKQDTLGFIWIGTQDGLNRYDSK 84