Pairwise Alignments
Query, 1450 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Subject, 1347 a.a., hypothetical protein from Pedobacter sp. GW460-11-11-14-LB5
Score = 492 bits (1266), Expect = e-142
Identities = 358/1301 (27%), Positives = 622/1301 (47%), Gaps = 156/1301 (11%)
Query: 251 HVSMINEVKKFDSNTLLLATDNGLIIYKIKEKEF-QLI--DIRTSTQPSNVVQSVYQDHY 307
H++++N K N + + T G+ Y + F QLI D + S + S+
Sbjct: 89 HITVLNGDAK---NRVWVGTQKGISYYDYADSRFHQLIYLDKGRKNEVSYAINSIAISQA 145
Query: 308 KELWIFPQTTGV--IRYNPSTKEMQHLFTPADEVIRYERKNKNVIFEDRQHTLWVLPPEG 365
+++ + G+ ++ N S E D ++ ++ D TLW+ +
Sbjct: 146 LAVYVATEEKGLFMLKKNSSLAERIPFGKNFDFTVK-------ALYIDDDQTLWLFIKDV 198
Query: 366 NLSYYDRENKELKPMLKDSNNPKSVFSPL--VRFYTLDNQGNCWLTSTRGIYKLSFFPHT 423
L YD KD N + V + L V T D + WL + RG+++ +
Sbjct: 199 GLCKYD----------KDQNKVRLVTAALSSVTCITKDTKQTLWLGTERGLFQFDKVKAS 248
Query: 424 YNLV--HIDNGFETRAFLCDNEKRLWVSSKAQMIRVYQPDGQLEGYLTPQGKISKDKQSF 481
+ H++N L D +++LW+S+ + VY Q YL+ GK K S
Sbjct: 249 ISKFNQHLNNE-NIMGLLLDRQQKLWISTDGGGVAVYDTKKQKTSYLSA-GK-EKGLLSS 305
Query: 482 TSVYCFLEDHEGNIWIGTKENGIYLLKKKSPDSYSVQQFT---HQPNMPYSLSGNSVYSI 538
SV EDHE WI T G+ ++ ++ +QFT H P SL N V S
Sbjct: 306 NSVAQVYEDHESRKWIATLRGGVNIIDTEN------EQFTTIKHDPLKSNSLINNFVLSF 359
Query: 539 FQDSHKRIWIGCYGGGIN-----LLTYNKDGKTEFIHSDNEL-KNYPTGYASKVRH---I 589
+D +K IWIG GGG++ L T+ KT N L N+ T + H +
Sbjct: 360 SEDENKNIWIGTDGGGLSVWNRKLNTFANYAKTS---DPNSLTSNFVTSILNDADHNVWV 416
Query: 590 SEAPGGVLLIGTTNGLLTFSNQFERPEEI------KFYRNCCES-GISTSLSG------- 635
+ GG+ T G N + + + K Y++ ++ + T+ G
Sbjct: 417 ASFSGGIDRFNKTTGKFVHYNCYNTSKGVDDINIWKLYQDKQQNIWVGTTKGGALYRYNK 476
Query: 636 ------------NDVMHTYTDKQKRTYIASFTGGIS-QIVSKNLLSNKIEF--------- 673
D+ + D + R + ++T I V+K KI F
Sbjct: 477 SIDKFELFDTKLKDIHSLFQDSKGRLWAGNYTELIEIDPVNKKHNYTKINFAIRAIQEDF 536
Query: 674 -----------------------KTYTTDDGLASDLVQAMQEDQQGNLWILSENAISKFD 710
K Y DGL S+ V + +D QGNLW + N +S+FD
Sbjct: 537 NHQIWIGTEGGGLLLFDPETKKIKRYIQSDGLPSNSVLNILQDAQGNLWCSTYNGLSRFD 596
Query: 711 AQRKTFENYGLNSLHQEFSFSEAAPVINARNQIVFGTDKGFIEISSKEMQKSSYVPPIVF 770
+ +F+NY Q F+ A + A +FG GF S ++K+ +P +V
Sbjct: 597 VRHHSFKNYYATDGLQSNQFNYNAALKLANGNFLFGGIGGFNLFSPDSIKKNKRIPKMVL 656
Query: 771 TGLKVQG----QSSV---IAIDDLEELRLTPSQRNVTFQFAALDYVDSKEIRYAYRLKGL 823
T ++ Q S I++ +L + + S ++ +AA+++ +I YAY L+G
Sbjct: 657 TDFRINNIPLDQDSAYNDISVINLARIEIPFSDAVISIDYAAIEFSFQDQISYAYYLEGW 716
Query: 824 EEEWHDGDKNRSASYINLPNGKYKLQIKSTNSDGVWMDNIRTLSINVLPTFWETGWAWLL 883
+ +W+ +K +A Y L G+YKL IKST+++G W +N + + I +LP ++ T WA+ +
Sbjct: 717 DRDWNYVNKLSTAYYSRLNEGEYKLHIKSTDTEGAWSNNEKIVVIRILPPWYRTWWAYTI 776
Query: 884 YVILFVLFTGSIVYVLFYIYR-----LRHQVDI-------EQQLSNIKLRFFTDISHELR 931
Y+I+ GS ++ LF YR L+H+V+I E+ L+ KL FFT+ISHELR
Sbjct: 777 YLII-----GSSIFYLFQTYRNRQRRLKHEVEITNLKMEREKDLNEKKLNFFTNISHELR 831
Query: 932 TPLTLISSPVNEVLENEDLSATAREHLTVVQKNAERMLRLMNQILDFRKIQNQKMKVLVE 991
TPLTLI +P+ +++ +D + L +V +N+ R+L L++Q+L FRK +++ + +
Sbjct: 832 TPLTLIVNPIKDIILKKD-PGPEKNDLNIVYRNSRRLLSLVDQLLLFRKTESENDTLKIV 890
Query: 992 KTDLIPLLEKVMINFRLIAEEKKINFRLASELKSIYAWIDRDKFEKIFFNLISNAFKYTP 1051
+ +L ++ + F +A++ I++ E + + + D+DK E +FFNL+SNA K+TP
Sbjct: 891 RINLYKFTNEIFLCFNYLAKQNHIDYTFECEEEELDIYADKDKLEIVFFNLLSNALKFTP 950
Query: 1052 AEKAITIEVTKQTDKVTISVVDEGIGIEPTKLRTLFQRFETLAQQNMLQPSSGIGLSLVK 1111
+ V +V I V D G GI LF +F + L+ GIGL L K
Sbjct: 951 KGGFVKFSVKPLGMRVQIEVSDSGPGIPAHVGEKLFDKFYKVMSNESLKMGFGIGLYLAK 1010
Query: 1112 EMVDMHHGTIKVTSEPEAGSRFIVTLPLQKEVFEQDSQVEFILNDSQSPTTHPDSSLQTE 1171
V++H G I S G+ F++ +P+ + + Q+ T+ + + E
Sbjct: 1011 NFVELHKGKISFRSNQGMGTIFLIDIPVGEPNLQHSGVF-------QNELTYVNELIAQE 1063
Query: 1172 KRAEAEDKEDMEN--NTAPDTLTILVVEDNEELKAFLKNILSENYTVITASNGKEGLQHA 1229
+ AE D E + N D +ILV++DN E+ ++++I EN+ + A NG +GL+
Sbjct: 1064 EEAENNDTEHVGNLQLLISDLHSILVIDDNPEIIDYIRHIFQENFKIYKAENGTDGLKRC 1123
Query: 1230 VDNIPDLIISDVMMPVMDGLEMIRQIKENNNICHIPIIVLSAKASLDDRIAGLEQGIDDY 1289
+ +PD++ISDV M ++G+E+ + IK+++ + HIP+I+L+ S + ++ G+E G D+
Sbjct: 1124 KEYLPDIVISDVNMDGLNGIELCKAIKDDSALSHIPVILLTGDPSPEVKLKGIEVGAYDF 1183
Query: 1290 ITKPFSATYLKTRIASLLRQRKSLQEIYMAKLTEGKEIAVAEALTPSQPQITPYDEQFMQ 1349
I+KPF +I S+++ R +LQ + ++T L +++ D+ F+Q
Sbjct: 1184 ISKPFDRELFTAKINSIIKNRTNLQSYFYNEIT----------LKSDAHKVSQEDKGFLQ 1233
Query: 1350 KVMEFIEEQMDNAELTIDEFAEHLMLSRTIFYRKLKSIIGLTPVDFIREVRIKRAAQLID 1409
K + IEE + + A L +S + Y+++K+ G + FIR +R+++AA+L+
Sbjct: 1234 KCIMIIEENLMEDSFNVKILASDLGMSHSNLYKRIKATSGQSVNGFIRFIRLRKAAELLI 1293
Query: 1410 SGEYNFSQVAYMTGFNDPKYFSKCFKKVVGITPSEYKEKNK 1450
+ N ++ A+ G ND KYF + F+K+ +TPSE+ +K++
Sbjct: 1294 NTNLNINEAAFRVGINDSKYFREQFQKLFKLTPSEFIKKHR 1334
Score = 85.9 bits (211), Expect = 3e-20
Identities = 94/430 (21%), Positives = 174/430 (40%), Gaps = 63/430 (14%)
Query: 39 VQTIIQDKKGFLWFGTWNGLNKFDGYTFKNYKTSYKDGYILNTNRISQIAETKYGDIWCQ 98
V I +D K LW GT GL +FD K + K LN I + + +W
Sbjct: 220 VTCITKDTKQTLWLGTERGLFQFD----KVKASISKFNQHLNNENIMGLLLDRQQKLWIS 275
Query: 99 AYDGRVYMFDNQTEKFIDILGSVAETMITNN-----YADH-----IYTLSKGISWITFQN 148
G V ++D + +K + + ++++N Y DH I TL G++ I +N
Sbjct: 276 TDGGGVAVYDTKKQKTSYLSAGKEKGLLSSNSVAQVYEDHESRKWIATLRGGVNIIDTEN 335
Query: 149 ECAAIRIDDQLCKQGKGITLYSSFKQNLKGDKIYTVFEDSEGDEWILTNKGISIIGK--- 205
E D L K +L ++F + D+ ++ ++G + N+ ++
Sbjct: 336 EQFTTIKHDPL----KSNSLINNFVLSFSEDENKNIWIGTDGGGLSVWNRKLNTFANYAK 391
Query: 206 ----KQVDSDFPFQYIKEADGIIYLVSQSDKLASYNFKTRQFKFIEIPYHVSMINEVKKF 261
+ S+F + +AD +++ S S + +N T +F H + N K
Sbjct: 392 TSDPNSLTSNFVTSILNDADHNVWVASFSGGIDRFNKTTGKF------VHYNCYNTSKGV 445
Query: 262 DS-----------NTLLLATDNGLIIYKIKEK--EFQLIDIRTSTQPSNVVQSVYQDHYK 308
D + + T G +Y+ + +F+L D + + S++QD
Sbjct: 446 DDINIWKLYQDKQQNIWVGTTKGGALYRYNKSIDKFELFDTKLKD-----IHSLFQDSKG 500
Query: 309 ELWIFPQTTGVIRYNPSTKEMQHLFTPADEVIRYERKNKNVIFEDRQHTLWVLPPEGNLS 368
LW T +I +P K+ H +T + IR I ED H +W+ G L
Sbjct: 501 RLWA-GNYTELIEIDPVNKK--HNYTKINFAIR-------AIQEDFNHQIWIGTEGGGLL 550
Query: 369 YYDRENKELKPMLKDSNNPKSVFSPLVRFYTLDNQGNCWLTSTRGIYKLSFFPHTYNLVH 428
+D E K++K ++ P + +++ D QGN W ++ G+ + H++ +
Sbjct: 551 LFDPETKKIKRYIQSDGLPSNSVLNILQ----DAQGNLWCSTYNGLSRFDVRHHSFKNYY 606
Query: 429 IDNGFETRAF 438
+G ++ F
Sbjct: 607 ATDGLQSNQF 616
Score = 48.9 bits (115), Expect = 3e-09
Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 6/78 (7%)
Query: 16 ILVAQPTYQIKHYSVNDGMSQGIVQTIIQDKKGFLWFGTWNGLNKFD--GYTFKNYKTSY 73
+L T +IK Y +DG+ V I+QD +G LW T+NGL++FD ++FKNY +
Sbjct: 550 LLFDPETKKIKRYIQSDGLPSNSVLNILQDAQGNLWCSTYNGLSRFDVRHHSFKNYYAT- 608
Query: 74 KDGYILNTNRISQIAETK 91
DG L +N+ + A K
Sbjct: 609 -DG--LQSNQFNYNAALK 623
Score = 45.4 bits (106), Expect = 4e-08
Identities = 57/276 (20%), Positives = 105/276 (38%), Gaps = 32/276 (11%)
Query: 490 DHEGNIWIGTKENGIYLLKKKSPDSYSVQQFTHQPNMPYSLSGNSVYSIFQDSHKRIWIG 549
DH G +W+GT + D Y + F + +SL N + + D+ R+W+G
Sbjct: 51 DHFGFMWMGTYDG------LNRYDGYHFKVFRNGWGDEHSLVNNHITVLNGDAKNRVWVG 104
Query: 550 CYGGGINLLTYNKDGKTEFIHSDNELKNYPTGYASKVRHISEAPGGVLLIGTTNGLLTFS 609
G I+ Y + I+ D KN YA IS+A V + GL
Sbjct: 105 TQKG-ISYYDYADSRFHQLIYLDKGRKN-EVSYAINSIAISQALA-VYVATEEKGLFMLK 161
Query: 610 NQFERPEEIKFYRNCCESGISTSLSGNDVMHTYTDKQKRTYIASFTGGISQIVSKNLLSN 669
E I F +N + V Y D + ++ G+ + N
Sbjct: 162 KNSSLAERIPFGKNFDFT----------VKALYIDDDQTLWLFIKDVGLCKYDKDQ---N 208
Query: 670 KIEFKTYTTDDGLASDLVQAMQEDQQGNLWILSENAISKFDAQRKTFENYGLNSLHQEFS 729
K+ T A V + +D + LW+ +E + +FD + + + + ++
Sbjct: 209 KVRLVT------AALSSVTCITKDTKQTLWLGTERGLFQFDKVKASISKFNQHLNNENIM 262
Query: 730 FSEAAPVINARNQIVFGTDKGFIEISSKEMQKSSYV 765
+++ + ++ TD G + + + QK+SY+
Sbjct: 263 ----GLLLDRQQKLWISTDGGGVAVYDTKKQKTSYL 294
Score = 32.0 bits (71), Expect = 4e-04
Identities = 21/84 (25%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Query: 668 SNKIEFKTYTTDDGLASDLVQAMQEDQQGNLWILSENAISKFDAQR-KTFENYGLNSLHQ 726
S I K + GL++++V ++ D G +W+ + + ++++D K F N G H
Sbjct: 26 STAIPLKYLGVESGLSNNVVNSLYLDHFGFMWMGTYDGLNRYDGYHFKVFRN-GWGDEHS 84
Query: 727 EFSFSEAAPVINARNQIVFGTDKG 750
+ +A+N++ GT KG
Sbjct: 85 LVNNHITVLNGDAKNRVWVGTQKG 108