Pairwise Alignments
Query, 1354 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Subject, 1349 a.a., hybrid sensor histidine kinase/response regulator from Pedobacter sp. GW460-11-11-14-LB5
Score = 692 bits (1786), Expect = 0.0
Identities = 450/1365 (32%), Positives = 728/1365 (53%), Gaps = 74/1365 (5%)
Query: 24 ITFSHLTTDDGLSQFSVNSLYIDERGIIWIGTREGLNRYNGNDIKSFKLKKNDPNSLFSN 83
++F HL+ ++GLSQ +V S+ D RG +W GTR+ LNRY+G +K ++ ++P S+ +
Sbjct: 8 LSFDHLSVNNGLSQSTVLSICKDSRGYMWFGTRDCLNRYDGKSVKIYRTDPDNPASISTE 67
Query: 84 TVLRIT----------GNKNG-KVYLLCTDGVAEFDMTTQRFKTLLQGNVDAIYYNE--K 130
+ G +NG Y+ D + ++ + +IY + K
Sbjct: 68 DYIYALEEDRQKNLWIGTQNGLNRYIPEKDAFERIAFDPKNANSISDKIILSIYADRSGK 127
Query: 131 LYIGKREEVFVF-NENTNNFDLYYH---LAGKDINLSCLHLDEKKNLWMGTTSN------ 180
++ G + + + N ++ F Y LAG + + D K N+W+GTT+
Sbjct: 128 VWFGTNQGLSMLENGSSRKFKKIYQKDGLAGNSVYT--IFEDSKGNIWVGTTTGLSRLSF 185
Query: 181 --GVYCL-SDDKQLSQP--ITKGNIASIYEDSSKELWIGSWEEGLYR-IRTNGTIDNFRH 234
G Y + S + P I+ +I +I ED +WIGS EGL + + + FR+
Sbjct: 186 KEGKYHIQSFYHRAGDPGSISGNSIRTIAEDGKGRIWIGSESEGLNLFLPQSHSFKRFRY 245
Query: 235 DPKNPNSICSDFVRSCCEDNLGNLWIGTFHGLNRYDKSTGQFQLYTANDNKPDGLTHSSI 294
PN++ +D VR D GNLWI T +GLN D T F Y + + L+ +SI
Sbjct: 246 SALQPNALSNDIVRKIMPDGKGNLWIATMNGLNILDTQTLGFTSYKHDADNRKSLSDNSI 305
Query: 295 WCIVKDEQGTLWLGTYFGGVNYFNPEYEIYTRYKVGDTEKEGLSSPIVGRMTEDKDGNLW 354
I +D+QG++W+GT FGGVN + +T +K + +SS I + D D NLW
Sbjct: 306 KEIFQDDQGSIWIGTMFGGVNVAHRNTIPFTVFKYSKY-RNSISSDISSVIAADNDQNLW 364
Query: 355 ICTEGGGVNVYNRKNNTYRWYRHE-EGKNSISHNNVKAIYYDRTEEIMWIGTHLGGLNKL 413
I TEG G+N YN K ++ Y ++ S+S+N +KAI+ DR I WIG + GGL
Sbjct: 365 IGTEGQGLNFYNVKTGLFKKYINDPRDPGSLSNNTIKAIFNDRKGRI-WIGLYQGGLELF 423
Query: 414 DLRTNRFTVYRM-KAGDPTTLPSDIVRDIVPYEDKLIIATQN-GVCLFNPATGTCEHLFK 471
T +F Y + G S I D + +L++ T + G+ +F+P + + +
Sbjct: 424 IPSTGKFKHYPPGRNGLSQGYLSSISEDD---QGRLLLGTSSKGLNIFDPEKESFQLI-- 478
Query: 472 DTKEGRNIGMVASL----YIDKDETLWVSATGEGVYSYRFDTGKLTHYAHNPSIPNTLSN 527
D + G + + +S Y D + LWV T G+ + ++ + +L +
Sbjct: 479 DDQPGHGLKLSSSYIRFAYQDTKKNLWVG-TPRGLNFLPPGANHFSVFSRDDKTKGSLKS 537
Query: 528 NNVNNIMQDSNGNLWFSTSGSGLDRYRKESNDFENFDMQKDGLSSDCIYEVFESSIQKGD 587
+ + + +D G++W T GL Y +S F + + GL+SD I +V + + G+
Sbjct: 538 SQITCLWEDRLGHIWVGTMRGGLSLYHPDSKSFSTYT-RAQGLASDNIIDVLDDN--DGN 594
Query: 588 LLLITNQGFSQFDYPQKKFYNYGTENGFPLTAVNENALFVTHDGEVFLGGIQGMISFWEK 647
L + T++G S+FDY + F NY T +G P N N+ + G+++ G G++ F +
Sbjct: 595 LWISTDRGLSKFDYKRGVFKNYNTGDGLPTNEFNVNSAYRDIHGKLYFGSYDGLVVFTPR 654
Query: 648 KLHFTPKSYSIILSRLLVNGKEITAGDDTGILEQSIAYTPEISLKADQSMFSIEYATSNF 707
++ + S L + K + +D G+L+Q I++T I+ A+Q++FS+E+ + N+
Sbjct: 655 EITENTLIPRTVFSGLKLFNKPVGINEDNGLLKQDISFTKGITFTAEQNIFSLEFVSLNY 714
Query: 708 IPANRNEIVYRLEGFSDEWNHTDRKQTLITYTNLNPGKYTLVIK-SDGDGIEEAR---LL 763
+ RN Y+LEGF +WN+ +YTNL G Y L++K S+ DG+ +
Sbjct: 715 VQPQRNRYAYKLEGFEKDWNYVTIPSA--SYTNLPSGNYKLLVKGSNNDGLWSKAPVVME 772
Query: 764 IRVLPPWYETWWAYLIYTICTVSLLWYLIQNYNSRIKLRESLKYEKKHIEDLEALNQSKL 823
IRVLPP ++TWWAY +Y I LL+++++ + KL+ L YE + E L Q KL
Sbjct: 773 IRVLPPLWQTWWAYTLYFIAGGLLLYFVLRFTRRQQKLKTELYYEHLNSERQSELYQMKL 832
Query: 824 RFFTNISHEFRTPLTLIVGQVETLLQVQTFTPNIYHKILGIYKNSLQLRELITELLDFRK 883
FFT ISHE RTPLTLI +E L+++ + ++ I +N+ +L LI+ELLDFRK
Sbjct: 833 DFFTRISHEIRTPLTLIFAPLEKLIKITAENGAVNLQLQNIKRNTDRLVRLISELLDFRK 892
Query: 884 QEQGHMKIKVSRHNLVNFLYENYLLFLEYASSKQINFKFNKQSDDIEVWYDQKQMQKVVN 943
E G++ +KVS ++LV+F + Y +L A K I+++F +++ + V+YD QM+KV
Sbjct: 893 IESGNLSLKVSENDLVSFCRQIYESYLGLAEIKNIDYRFECEAESMLVYYDPAQMEKVFY 952
Query: 944 NLLSNALKHTKAEDTISINVSQEDKYVIIEIKDTGTGIAAAEIDKIFDRFYQTERLDSLN 1003
N+LSNA K T I+ ++ Q D I I DTG GI A DKIF F+Q + +
Sbjct: 953 NILSNAFKFTPDNGKITFSLKQSDGLAKIAITDTGIGIPADLQDKIFTNFFQVK--NGAA 1010
Query: 1004 TGAGTGIGLALTKGIIELHHGTIRVESEPGKGSRFIIT-----LKSGNQHFTEEQIIRDN 1058
G GIGLAL K I++LH G + V SEP R IT L G HF++EQI
Sbjct: 1011 ATEGWGIGLALAKNILDLHKGEVNVYSEPANNKRQGITILHVSLLLGKNHFSDEQI---- 1066
Query: 1059 ADANIQQPPETIVPTVEILPDSEWKEEDNKRIEDAK---MLIVEDNESIKQMLVGIFETF 1115
P T P D E + ED K +L+VEDN+ ++ +V +
Sbjct: 1067 ----ASNPIVTDKPVAVGSLDHELAKIQLVAPEDKKRHTVLVVEDNDELRDFIVQSLKHT 1122
Query: 1116 YQVTTASDGVEALDIIQKDMPSIILSDVVMPRMSGTELCKQVKTDFNTCHIPVVLLTART 1175
Y + +G+ ++ + +P I++SDV MP ++G ELC+++K + T HIPV++LTA
Sbjct: 1123 YHILEGKNGLVGWEVATEHVPDIVVSDVTMPELNGFELCQRLKQEETTNHIPVIMLTAMA 1182
Query: 1176 AVEHNIEGLKIGADDYITKPFNTNLLISRCNNLVNSRRLLQEKFSKQPQAFAQMLATNPM 1235
+ H I+GL+ GAD YITKPF+ +L NL+ R L++K+ KQ + L T
Sbjct: 1183 SHVHQIDGLEAGADVYITKPFSIQVLELSIRNLLQGREELRQKYIKQIMLNPRKLETASP 1242
Query: 1236 DKEMLDRAMAIIEQHLDNTDFNVNIFAREMGMARTNLFTKLKAVTGQTPNDFILSIRLKK 1295
+++ L+R M +IE +++ +FNV ++GM++T L+ K+KA+TG + +DFI S RLK+
Sbjct: 1243 EEKFLNRLMQLIEDGMEDPEFNVGGLVDQIGMSQTVLYKKIKALTGLSISDFIKSQRLKR 1302
Query: 1296 GAVMLRNNPELNITEISDRIGFSSSRYFSKCFKEIYHVSPLAYRK 1340
A +L N+ ++NI E++ +GF+ +YFSK F++ + V+P Y++
Sbjct: 1303 AAQLL-NDHKMNIAEVAYSVGFNDRKYFSKEFRKQFGVAPSEYQQ 1346
Score = 152 bits (383), Expect = 3e-40
Identities = 135/493 (27%), Positives = 233/493 (47%), Gaps = 52/493 (10%)
Query: 21 GQNITFSHLTTDDGLSQFSVNSLYIDERGIIWIGTREGLNRYNGND----IKSFKLKKND 76
G + F + DGL+ SV +++ D +G IW+GT GL+R + + I+SF + D
Sbjct: 142 GSSRKFKKIYQKDGLAGNSVYTIFEDSKGNIWVGTTTGLSRLSFKEGKYHIQSFYHRAGD 201
Query: 77 PNSLFSNTVLRITGNKNGKVYLLC-TDGVAEFDMTTQRFK----TLLQGN------VDAI 125
P S+ N++ I + G++++ ++G+ F + FK + LQ N V I
Sbjct: 202 PGSISGNSIRTIAEDGKGRIWIGSESEGLNLFLPQSHSFKRFRYSALQPNALSNDIVRKI 261
Query: 126 YYNEK--LYIGKREEVFVFNENTNNFDLYYHLAG-----KDINLSCLHLDEKKNLWMGTT 178
+ K L+I + + + T F Y H A D ++ + D++ ++W+GT
Sbjct: 262 MPDGKGNLWIATMNGLNILDTQTLGFTSYKHDADNRKSLSDNSIKEIFQDDQGSIWIGTM 321
Query: 179 SNGV---------YCLSDDKQLSQPITKGNIASIYEDSSKELWIGSWEEGL--YRIRTNG 227
GV + + + I+ + I D+ + LWIG+ +GL Y ++T G
Sbjct: 322 FGGVNVAHRNTIPFTVFKYSKYRNSISSDISSVIAADNDQNLWIGTEGQGLNFYNVKT-G 380
Query: 228 TIDNFRHDPKNPNSICSDFVRSCCEDNLGNLWIGTFH-GLNRYDKSTGQFQLYTANDNKP 286
+ +DP++P S+ ++ +++ D G +WIG + GL + STG+F+ Y N
Sbjct: 381 LFKKYINDPRDPGSLSNNTIKAIFNDRKGRIWIGLYQGGLELFIPSTGKFKHYPPGRN-- 438
Query: 287 DGLTHSSIWCIVKDEQGTLWLGTYFGGVNYFNPEYEIYTRYKVGDTEKEG--LSSPIVGR 344
GL+ + I +D+QG L LGT G+N F+PE E + + D G LSS +
Sbjct: 439 -GLSQGYLSSISEDDQGRLLLGTSSKGLNIFDPEKESF--QLIDDQPGHGLKLSSSYIRF 495
Query: 345 MTEDKDGNLWICTEGGGVNVYNRKNNTYRWYRHEEGKNSISHNNVKAIYYDRTEEIMWIG 404
+D NLW+ T G + N+ + R ++ K S+ + + ++ DR I W+G
Sbjct: 496 AYQDTKKNLWVGTPRGLNFLPPGANHFSVFSRDDKTKGSLKSSQITCLWEDRLGHI-WVG 554
Query: 405 THLGGLNKLDLRTNRFTVYRMKAGDPTTLPSDIVRDIVPYED-KLIIATQNGVCLFNPAT 463
T GGL+ + F+ Y G L SD + D++ D L I+T G+ F+
Sbjct: 555 TMRGGLSLYHPDSKSFSTYTRAQG----LASDNIIDVLDDNDGNLWISTDRGLSKFDYKR 610
Query: 464 GTCEHLFKDTKEG 476
G +FK+ G
Sbjct: 611 G----VFKNYNTG 619