Pairwise Alignments
Query, 1343 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Subject, 1374 a.a., hypothetical protein from Pedobacter sp. GW460-11-11-14-LB5
Score = 513 bits (1321), Expect = e-149
Identities = 373/1379 (27%), Positives = 662/1379 (48%), Gaps = 136/1379 (9%)
Query: 37 KQLSITEGLSHNTVNAISQDSKGFMWFGTRNGLCRYDGYNITRYFHEEGDSTTISHDFIT 96
K I EGL + A +D +GF+W GT NGLC++DGY Y + GD+T++++++I
Sbjct: 40 KTYGINEGLPSKSTTAALKDKRGFIWVGTENGLCKFDGYAFKIYVNITGDTTSLTNNYIN 99
Query: 97 KLYNDPCRNVLWISTEQGICKYNPQNEQFTRYHIEGNNKNSVL------FLNTSDSRLLT 150
+ D V W+ T G+ K++P E+F R++ + NN+ S+ L ++L
Sbjct: 100 AVVEDK-NGVFWVGTMNGLNKFDPVTEKFERFYHKENNRTSLSNNKIWSLLIDRTNKLWV 158
Query: 151 GCSNGIYQYDNEKNSFTPFILNEG-----KGENIRGLVEDSNNVLWI-NSNKGVKRYNLK 204
G +G ++ N+FT + + KG+++ + ED LW+ N +KG+ +++ K
Sbjct: 159 GTDDGFNLFNKNSNAFTVYQPDFKDPDAIKGKSVNAIAEDKAGNLWLGNWSKGLNKFDKK 218
Query: 205 KEQFEPLPLNIRPFLETCIQLVMLPGNQLLFNTPQEVFVYNINNDSLYPLAAIKDIRQFR 264
+ F+ N Q+ N + ++ L
Sbjct: 219 TKSFK--------------------------NYTQKEVAGEKNPNDIWTL---------- 242
Query: 265 CATTDTMNNIWLGT--ENGIFIYDQTFRLVTHYQQ----SESDLSNLNDSPIYSLFEDYN 318
C D M IW+G+ + +F +D T Y + S S LN L
Sbjct: 243 CLDADGM--IWIGSYWKGDLFRFDPKSESFTTYASKGTGNASIFSVLNLGTEKLLVGGSA 300
Query: 319 HNMWVGTYFGG----------VNYFIYASDQFRIYPYGNSP-----------NHLS---G 354
WV T N +Y I+ G + N +S G
Sbjct: 301 GVFWVNTKLNKWEKIEELEFFANGGLYRDKSGMIWICGKNGFSKIDFNQYKFNFISLPFG 360
Query: 355 KAVRQIINTPDNGLYIATEDGGLNYLNSNREITRSERLHERMNIKARNIHSLLIDSKQNL 414
+A + I + ++ T G Y N +++ + ++ + I +L D K L
Sbjct: 361 QAEIKSIISYGKDFWVGTNKGLFKYNPDNHAVSKLQHTGNPNSLSSSEIINLSTDLKNRL 420
Query: 415 WIGLFLRGMNYYMPKENKTLSFND----GMGKNSSGFC-IIEDETGKIWYGGPSGLFTLK 469
W+ + G + Y K NK + + G N F +IE + + +GL
Sbjct: 421 WV-MGENGFDRYDEKANKFIHHHHRSALGSFFNEDVFRDLIEVNADEYYLATDAGLKVYN 479
Query: 470 KQNGSF--------QLKKVSALPVFCMLNLNDSIIWTGNRQNGIYQINKRTEEQTPLPQF 521
+ S+ +S ++C+L +W G +G+ + N +T + +
Sbjct: 480 DKTNSYTHYFNDPKNQASLSNNHLYCLLKDAQGNVWIGTYGSGLSRFNPKTRKFSNYMIN 539
Query: 522 SS-----SKLYMTYLYMDSQGNIWAGTNNDGLFVLNKKGEKLKSYSKKE-LGSNAIKGII 575
+S S + LY+DS N+W T DGL K + YSK+ SN ++
Sbjct: 540 NSKRGGISNNIVNSLYLDSHQNVWVCTR-DGLNKYIAKTNTFEIYSKQNGFASNVFTDLV 598
Query: 576 EDDQNTIWIGTDNGLCNIQPKSGLISRYTIADGLPTNQFNYSSVCKKPDGELFFGTINGM 635
ED+ +W+ T+ G+ P S ++ Y DG+ N +++CK GE++ G+
Sbjct: 599 EDNNGRLWVTTEQGISLFDPVSKMVKNYDEKDGVYAN----AAICKNAKGEIYLAGSKGI 654
Query: 636 ISFYPEQVRPVEPHFNIALTGVWSNNDVVSSS----NPDALLPASISESDVMTLTHEQAQ 691
+ F P+ ++ +N V+ ++ + + D+ L + + +TL + Q+
Sbjct: 655 VYFNPQLLK-----YNKTAPAVYFSDFSIFNKLILPGDDSPLKLPVYMTREITLPYSQSV 709
Query: 692 SIRIEYSGLNYQYKDKTQYAMKLEGIDKEWQFVGNQHQVRFSNLPTGDYTLKIKASNDGV 751
+ + LNY +K +YA LEG DK+W + G++H+V ++NL G Y LK++ASN+
Sbjct: 710 -LSFGFVALNYTLSEKNKYAYFLEGFDKKWNYSGSEHKVTYTNLNPGKYVLKVRASNNDG 768
Query: 752 NWDEKGQKELTIHVLPPWWLSIWAYLTYVCMVLCIIYLAYKYTKARLILLMRLKTEHEQR 811
W+ +G + I + PPW+ + WA+ Y +IY KY + R L ++K H +
Sbjct: 769 IWNMEGNS-IGITITPPWYRTWWAFCIYGLTFFGMIYAYLKYREHRANLEFQVKLAHVES 827
Query: 812 VNMEKMNQSKINFFTYVSHDLKTPLTLILSPLQRLIKQKQIDNNDREKLEVIYRNANRMH 871
+++++ K++FFT VSH+ +TPLTLI++P++ L+ K N D L ++YRNA R+
Sbjct: 828 EKEKELSEKKLSFFTNVSHEFRTPLTLIINPVKELL-YKNDKNVDTTDLNIVYRNAKRLL 886
Query: 872 YLIDELLTFSKIEMQQMEINVRKGNIMHFLEEISHIFDIVSKEKEIDFIVSLEETDEEVW 931
L+D+LL F K + ++ V N++ +E+ F ++ K I ++ TDE +
Sbjct: 887 SLVDQLLLFRKADTYGEKLKVAPVNLVSLCKEVFLCFVHQARSKNI--VLDFIGTDEVIP 944
Query: 932 F--SPSKLERIMYNLLSNAFKYTQPGDYVKLSAKLLKKDSENFIEISVKDSGRGIPKEMK 989
F K+E + +NLLSNA K+T G VK+ +D I++ ++D+G GI
Sbjct: 945 FYADREKIEIVFFNLLSNAIKFTPEGGTVKMIVGNRGED----IQVGIEDTGCGITTVAG 1000
Query: 990 DKIFDSYFQVE-KKDHREGFGLGLSLTKSLIHMHKGEIKVESEVGKGSEFIVSLNVSESA 1048
+K+++ ++Q K + GFG+GL L K+ I MH G I S KG+ F +SL S
Sbjct: 1001 EKLYEKFYQDPGNKSAKGGFGIGLYLAKNFIEMHGGTINYTSTENKGTIFNISLRRGISH 1060
Query: 1049 YSSSEKSLESITS------EEIQKYNLRMKETIELIPDQLISTEQDNTDVKESILIVEDN 1102
+ + E++ +E+ + + + +E + LI + Q D+K ++LI++DN
Sbjct: 1061 FKDAVILQEALVDTDSSLFKELIEDEITANKIVEAAEEPLIDS-QLALDLK-TLLIIDDN 1118
Query: 1103 KEMNDYLAEIFSKDYQVFRAYNGAEACKLLKKQLPDLIVSDVMMPVMDGLELTAYVKQDL 1162
E+ +YL ++F DY ++ A NG + ++K+ LPD+++ DVMM + G+EL + +K+D+
Sbjct: 1119 IEIREYLKQVFRMDYHLYEAGNGEDGYDMVKELLPDIVICDVMMDGITGIELCSKIKEDV 1178
Query: 1163 NSSHIPVILLTAKTDELDHTQGYLKGADAYITKPFNAQNLELLVQNMRTNRKQNIEYFKR 1222
SHIP+ILLTA + +G GAD YI+KPF+ L+ V ++ ++ YF
Sbjct: 1179 AVSHIPIILLTAISAPEVKLKGIEGGADDYISKPFDKDFLKARVASILKSKNALQRYFYN 1238
Query: 1223 IEKLNITQITNNPRDEVFMKELVDLIMANIKDEEFGVTEIITHMKVSRSLLHTKLKSLTG 1282
LN + + F+ + ++ ++ D +F + + + +SRS L+ K+KS++G
Sbjct: 1239 EITLNSNNTKISAEYKEFLDHCIRIVEEHLIDPDFNIDTLTATIGMSRSNLYRKIKSISG 1298
Query: 1283 CSITQFMRTIKM-KEAKIHLQNGMNVSEASYAVGMSDPNYFTKCFKKEFNITPTEFIKQ 1340
S F+R I++ K A+I + + E SY VG++DP YF + F + FN+ P+++IK+
Sbjct: 1299 QSANGFIRFIRLRKAAEIFINTDKTIQETSYMVGINDPKYFREQFYRLFNMNPSQYIKK 1357
Score = 103 bits (258), Expect = 9e-26
Identities = 106/392 (27%), Positives = 171/392 (43%), Gaps = 46/392 (11%)
Query: 231 NQLLFNTPQEVFVYNINND--SLYPLAAIKDIRQFRCATTDTMNNIWLGTENGIFIYD-Q 287
NQ + + Y IN S AA+KD R F IW+GTENG+ +D
Sbjct: 29 NQPVLTGHYVIKTYGINEGLPSKSTTAALKDKRGF----------IWVGTENGLCKFDGY 78
Query: 288 TFRLVTHYQQSESDLSNLNDSPIYSLFEDYNHNMWVGTYFGGVNYFIYASDQF-RIYPYG 346
F++ Y D ++L ++ I ++ ED N WVGT G+N F +++F R Y
Sbjct: 79 AFKI---YVNITGDTTSLTNNYINAVVEDKNGVFWVGT-MNGLNKFDPVTEKFERFYHKE 134
Query: 347 NSPNHLSGKAVRQIINTPDNGLYIATEDG-GLNYLNSNREITRSERLHERMNIKARNIHS 405
N+ LS + ++ N L++ T+DG L NSN + IK +++++
Sbjct: 135 NNRTSLSNNKIWSLLIDRTNKLWVGTDDGFNLFNKNSNAFTVYQPDFKDPDAIKGKSVNA 194
Query: 406 LLIDSKQNLWIGLFLRGMNYYMPKENKTLSFNDGMGKNSSG-------FCIIEDETGKIW 458
+ D NLW+G + +G+N + + KT SF + K +G + + D G IW
Sbjct: 195 IAEDKAGNLWLGNWSKGLNKF---DKKTKSFKNYTQKEVAGEKNPNDIWTLCLDADGMIW 251
Query: 459 YGG--PSGLFTLKKQNGSFQL---KKVSALPVFCMLNLNDSIIWTGNRQNGIYQIN---K 510
G LF ++ SF K +F +LNL + G G++ +N
Sbjct: 252 IGSYWKGDLFRFDPKSESFTTYASKGTGNASIFSVLNLGTEKLLVGG-SAGVFWVNTKLN 310
Query: 511 RTEEQTPLPQFSSSKLYMTYLYMDSQGNIWAGTNNDGLFVLNKKGEKLKSYSKKELGSNA 570
+ E+ L F++ LY D G IW N G ++ K ++ G
Sbjct: 311 KWEKIEELEFFANGG-----LYRDKSGMIWICGKN-GFSKIDFNQYKF-NFISLPFGQAE 363
Query: 571 IKGIIEDDQNTIWIGTDNGLCNIQPKSGLISR 602
IK II ++ W+GT+ GL P + +S+
Sbjct: 364 IKSIISYGKD-FWVGTNKGLFKYNPDNHAVSK 394
Score = 78.2 bits (191), Expect = 5e-18
Identities = 79/362 (21%), Positives = 147/362 (40%), Gaps = 74/362 (20%)
Query: 33 NVRFKQLSITEGLSHNTVNAISQDSKGFMWFGTRNGLCRYDGYN------ITRYFHEEGD 86
N + + E L + +D G +W +NG + D +N I+ F +
Sbjct: 306 NTKLNKWEKIEELEFFANGGLYRDKSGMIWICGKNGFSKID-FNQYKFNFISLPFGQAEI 364
Query: 87 STTISH--DFITKLYNDPCRNVLWISTEQGICKYNPQNEQFTRYHIEGN----NKNSVLF 140
+ IS+ DF W+ T +G+ KYNP N ++ GN + + ++
Sbjct: 365 KSIISYGKDF-------------WVGTNKGLFKYNPDNHAVSKLQHTGNPNSLSSSEIIN 411
Query: 141 LNTS-DSRLLTGCSNGIYQYDNEKNSFTPFILNEGKG-----ENIRGLVEDSNNVLWINS 194
L+T +RL NG +YD + N F G + R L+E + + ++ +
Sbjct: 412 LSTDLKNRLWVMGENGFDRYDEKANKFIHHHHRSALGSFFNEDVFRDLIEVNADEYYLAT 471
Query: 195 NKGVKRYNLKKEQFEPLPLNIRPFLETCIQLVMLPGNQLLFNTPQEVFVYNINNDSLYPL 254
+ G+K YN K + FN P+ +++N+ LY
Sbjct: 472 DAGLKVYNDKTNSYTH-----------------------YFNDPKN--QASLSNNHLY-- 504
Query: 255 AAIKDIRQFRCATTDTMNNIWLGT-ENGIFIYDQTFRLVTHYQQSESDLSNLNDSPIYSL 313
C D N+W+GT +G+ ++ R ++Y + S ++++ + SL
Sbjct: 505 ----------CLLKDAQGNVWIGTYGSGLSRFNPKTRKFSNYMINNSKRGGISNNIVNSL 554
Query: 314 FEDYNHNMWVGTYFGGVNYFIYASDQFRIYPYGNSPNHLSGKAVRQIINTPDNGLYIATE 373
+ D + N+WV T G+N +I ++ F IY + N + ++ + L++ TE
Sbjct: 555 YLDSHQNVWVCTR-DGLNKYIAKTNTFEIY---SKQNGFASNVFTDLVEDNNGRLWVTTE 610
Query: 374 DG 375
G
Sbjct: 611 QG 612
Score = 42.0 bits (97), Expect = 4e-07
Identities = 44/157 (28%), Positives = 63/157 (40%), Gaps = 21/157 (13%)
Query: 489 LNLNDSIIWTGNRQNGIYQINKRTEEQTPLPQFSSSKLYMTYLYMDSQGNIWAGTNNDGL 548
L N+ + TG+ Y IN+ LP S+ T D +G IW GT N GL
Sbjct: 25 LRTNNQPVLTGHYVIKTYGINEG------LPSKST-----TAALKDKRGFIWVGTEN-GL 72
Query: 549 FVLNKKGEKLKSY-----SKKELGSNAIKGIIEDDQNTIWIGTDNGLCNIQPKSGLISRY 603
+ G K Y L +N I ++ED W+GT NGL P + R+
Sbjct: 73 CKFD--GYAFKIYVNITGDTTSLTNNYINAVVEDKNGVFWVGTMNGLNKFDPVTEKFERF 130
Query: 604 TIADGLPTNQFNYS--SVCKKPDGELFFGTINGMISF 638
+ T+ N S+ +L+ GT +G F
Sbjct: 131 YHKENNRTSLSNNKIWSLLIDRTNKLWVGTDDGFNLF 167