Pairwise Alignments
Query, 1346 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Subject, 1374 a.a., hypothetical protein from Pedobacter sp. GW460-11-11-14-LB5
Score = 456 bits (1173), Expect = e-132
Identities = 367/1401 (26%), Positives = 649/1401 (46%), Gaps = 175/1401 (12%)
Query: 16 VAQTYQYLGVEDGLSNRRVYYIQKDNVGYMWFLTHEGIDRYNGKEFKRYKLMDGDKELNS 75
V +TY G+ +GL ++ KD G++W T G+ +++G FK Y + GD +
Sbjct: 38 VIKTY---GINEGLPSKSTTAALKDKRGFIWVGTENGLCKFDGYAFKIYVNITGDTTSLT 94
Query: 76 LLNLNWLYIDPEGTLWEIGKKGKIFRYDRIHDTFELVYKLPIEDFKDLPAPITFSWIDHN 135
+N + D G W +G + ++D + + FE Y I ID
Sbjct: 95 NNYINAVVEDKNGVFW-VGTMNGLNKFDPVTEKFERFYHKENNRTSLSNNKIWSLLIDRT 153
Query: 136 NHIWLCNEETIFLYNTRTEEVTHVKNCLSE-------AINDIEQIDESHYFIGT-EMGIH 187
N +W+ ++ L+N + T + + ++N I + + ++G G++
Sbjct: 154 NKLWVGTDDGFNLFNKNSNAFTVYQPDFKDPDAIKGKSVNAIAEDKAGNLWLGNWSKGLN 213
Query: 188 H-----AQLKNNTLQLLPCDKLDNVNIQVNDLHFDPKIRKLFIGAFERGVMV-YDMNTKT 241
KN T + + +K N +I L D I +IG++ +G + +D +++
Sbjct: 214 KFDKKTKSFKNYTQKEVAGEKNPN-DIWTLCLDADGMI---WIGSYWKGDLFRFDPKSES 269
Query: 242 ITQ-PEVSLKDVSISRIKPLNAKELLIATDGGGIYKMNVDTYQTVPFIVADYNSYNGMNG 300
T + SI + L ++LL+ G++ +N + ++ + G+
Sbjct: 270 FTTYASKGTGNASIFSVLNLGTEKLLVG-GSAGVFWVNTKLNKWEKIEELEFFANGGL-- 326
Query: 301 NSINDIYIDDEERIWMANYPIGITIQNNRYPSYKWIKHSVGNKQSLINDQVNSIIEDSEG 360
Y D IW+ I N+Y + +I G + + SII +
Sbjct: 327 ------YRDKSGMIWICGKNGFSKIDFNQY-KFNFISLPFGQAE------IKSIISYGK- 372
Query: 361 DLWYGTNNGISLQDSKTGKWRSFLSTFENVQNSKNHIFTTLCEVSPGI---IWAGGYFSG 417
D W GTN G+ K +S ++ N + + + +S + +W G +G
Sbjct: 373 DFWVGTNKGLF----KYNPDNHAVSKLQHTGNPNSLSSSEIINLSTDLKNRLWVMGE-NG 427
Query: 418 LYQIDKRTSKTTYFTPASYAHESIRPDKYIRDIRKDSRGYVWSGGYYNLKRINVQTKDIR 477
+ D++ +K + + H S + D+ +D
Sbjct: 428 FDRYDEKANKFIH-----HHHRSALGSFFNEDVFRD------------------------ 458
Query: 478 LYHGLHSVTAIIEKDDKSMWIGTATGLFLLDIESGKYERI------QLPVESTYVYSLYQ 531
+IE + ++ T GL + + ++ Y Q + + ++Y L +
Sbjct: 459 ----------LIEVNADEYYLATDAGLKVYNDKTNSYTHYFNDPKNQASLSNNHLYCLLK 508
Query: 532 TKQGSLYIGTSGSGVLIYDPQTKLFTHYYTGNCAM--ISNNIYTILS-DEDNEILLSTEN 588
QG+++IGT GSG+ ++P+T+ F++Y N ISNNI L D + + T +
Sbjct: 509 DAQGNVWIGTYGSGLSRFNPKTRKFSNYMINNSKRGGISNNIVNSLYLDSHQNVWVCTRD 568
Query: 589 GLTSFYPKQKTFYNWTKEMGLMTTHFNAL----SGTL----------------------- 621
GL + K TF ++K+ G + F L +G L
Sbjct: 569 GLNKYIAKTNTFEIYSKQNGFASNVFTDLVEDNNGRLWVTTEQGISLFDPVSKMVKNYDE 628
Query: 622 ------------RRNNNFIFGSSDGAIEFNKDMKLPRTYSSKMIFSDFKLFYQTVYPGDK 669
S G + FN + + + FSDF +F + + PGD
Sbjct: 629 KDGVYANAAICKNAKGEIYLAGSKGIVYFNPQLLKYNKTAPAVYFSDFSIFNKLILPGD- 687
Query: 670 NSPLEKDINETKELRLKYNQNIFSLMVSSINYDYPSNVLYSWKLEEFYEEWSKPGNESTI 729
+SPL+ + T+E+ L Y+Q++ S ++NY Y++ LE F ++W+ G+E +
Sbjct: 688 DSPLKLPVYMTREITLPYSQSVLSFGFVALNYTLSEKNKYAYFLEGFDKKWNYSGSEHKV 747
Query: 730 RYTNLAPGKYVLRVRAISNEDQRVMLEERSIDIIIAQPFWLTPWAMILYAILI------- 782
YTNL PGKYVL+VRA SN D +E SI I I P++ T WA +Y +
Sbjct: 748 TYTNLNPGKYVLKVRA-SNNDGIWNMEGNSIGITITPPWYRTWWAFCIYGLTFFGMIYAY 806
Query: 783 --------SLIAVIILRVLILKKQRKVSDEKIHFFINTAHDIRTPLTLIKAPLEDLREKE 834
+L + L + +K++++S++K+ FF N +H+ RTPLTLI P+++L K
Sbjct: 807 LKYREHRANLEFQVKLAHVESEKEKELSEKKLSFFTNVSHEFRTPLTLIINPVKELLYKN 866
Query: 835 ALSKEGIANMNTAIRNVNALLRLTTNLINFERADVYSSELYISEHELNTFMTEIFNAFQP 894
+ + ++N RN LL L L+ F +AD Y +L ++ L + E+F F
Sbjct: 867 DKNVD-TTDLNIVYRNAKRLLSLVDQLLLFRKADTYGEKLKVAPVNLVSLCKEVFLCFVH 925
Query: 895 YANIKHINFTYESNFRYMNVWFDKEKMESILKNIISNALKYTPENGNVQIFVSENNDSWS 954
A K+I + + + D+EK+E + N++SNA+K+TPE G V++ V +
Sbjct: 926 QARSKNIVLDFIGTDEVIPFYADREKIEIVFFNLLSNAIKFTPEGGTVKMIVGNRGEDIQ 985
Query: 955 VEVKDTGIGIPASEQKKLFKLHFRGSNAINSKVTGSGIGLMLVWKLVRLHKGKINLSSVE 1014
V ++DTG GI +KL++ ++ ++K G GIGL L + +H G IN +S E
Sbjct: 986 VGIEDTGCGITTVAGEKLYEKFYQDPGNKSAK-GGFGIGLYLAKNFIEMHGGTINYTSTE 1044
Query: 1015 NQGSVIKISFP------KDSKRFHKAHLATPSKR-----RQEITSTTNVPASIYENVHKE 1063
N+G++ IS KD+ +A + T S EIT+ V A+ + +
Sbjct: 1045 NKGTIFNISLRRGISHFKDAVILQEALVDTDSSLFKELIEDEITANKIVEAAEEPLIDSQ 1104
Query: 1064 QNPNHQRILIVEDNDELRNYLSQTLAEEYTVQNCCNGKEALTIIPEYKPELVISDIMMPE 1123
+ + +LI++DN E+R YL Q +Y + NG++ ++ E P++VI D+MM
Sbjct: 1105 LALDLKTLLIIDDNIEIREYLKQVFRMDYHLYEAGNGEDGYDMVKELLPDIVICDVMMDG 1164
Query: 1124 MRGDELCDAIKNNIETSHIPVILLTALNNEKDILSGLQIGADEYIVKPFNIGILKATVSN 1183
+ G ELC IK ++ SHIP+ILLTA++ + L G++ GAD+YI KPF+ LKA V++
Sbjct: 1165 ITGIELCSKIKEDVAVSHIPIILLTAISAPEVKLKGIEGGADDYISKPFDKDFLKARVAS 1224
Query: 1184 LLINR-ALLRSKYGSLDMDDEDDHEDECINCSQDIDWK-FIANVRKNIEDNIDNPALTVD 1241
+L ++ AL R Y + ++ N ++K F+ + + +E+++ +P +D
Sbjct: 1225 ILKSKNALQRYFYNEITLNSN--------NTKISAEYKEFLDHCIRIVEEHLIDPDFNID 1276
Query: 1242 VLCNLMGMSRTSFYNKLRALTDQAPGDYIRLIRLKRSVKLLKEGTHSITEIAEMTGFSDA 1301
L +GMSR++ Y K+++++ Q+ +IR IRL+++ ++ +I E + M G +D
Sbjct: 1277 TLTATIGMSRSNLYRKIKSISGQSANGFIRFIRLRKAAEIFINTDKTIQETSYMVGINDP 1336
Query: 1302 KYFREVFKKHFNVSPSQYGKE 1322
KYFRE F + FN++PSQY K+
Sbjct: 1337 KYFREQFYRLFNMNPSQYIKK 1357
Score = 57.0 bits (136), Expect = 1e-11
Identities = 59/282 (20%), Positives = 113/282 (40%), Gaps = 52/282 (18%)
Query: 335 WIKHSVGNKQSLINDQVNSIIEDSEGDLWYGTNNGISLQDSKTGKWRSFLSTFENVQNSK 394
++ + G + L + + ++D G +W GT NG+ D ++ +++ + +
Sbjct: 37 YVIKTYGINEGLPSKSTTAALKDKRGFIWVGTENGLCKFDGYA--FKIYVNITGDTTSLT 94
Query: 395 NHIFTTLCEVSPGIIWAGGYFSGLYQIDKRTSKTTYFTPASYAHESIRPDKYIRDIRKDS 454
N+ + E G+ W G +GL + D T K F Y E+ R S
Sbjct: 95 NNYINAVVEDKNGVFWV-GTMNGLNKFDPVTEKFERF----YHKENNRTSL--------S 141
Query: 455 RGYVWSGGYYNLKRINVQTKDIRLYHGLHSVTAIIEKDDKSMWIGTATGLFLLDIESGKY 514
+WS +I++ +K +W+GT G L + S +
Sbjct: 142 NNKIWS--------------------------LLIDRTNK-LWVGTDDGFNLFNKNSNAF 174
Query: 515 ERIQL------PVESTYVYSLYQTKQGSLYIGTSGSGVLIYDPQTKLFTHYYTGNCA--M 566
Q ++ V ++ + K G+L++G G+ +D +TK F +Y A
Sbjct: 175 TVYQPDFKDPDAIKGKSVNAIAEDKAGNLWLGNWSKGLNKFDKKTKSFKNYTQKEVAGEK 234
Query: 567 ISNNIYTILSDEDNEILLST--ENGLTSFYPKQKTFYNWTKE 606
N+I+T+ D D I + + + L F PK ++F + +
Sbjct: 235 NPNDIWTLCLDADGMIWIGSYWKGDLFRFDPKSESFTTYASK 276
Score = 55.5 bits (132), Expect = 3e-11
Identities = 46/198 (23%), Positives = 84/198 (42%), Gaps = 22/198 (11%)
Query: 428 TTYFTPASYAHESIRPDKYIRDIRKDSRGYVWSG---------GYYNLKRINVQTKDIRL 478
T ++ +Y P K KD RG++W G GY +N+ L
Sbjct: 34 TGHYVIKTYGINEGLPSKSTTAALKDKRGFIWVGTENGLCKFDGYAFKIYVNITGDTTSL 93
Query: 479 YHGLHSVTAIIEKDDKSMWIGTATGLFLLDIESGKYERI------QLPVESTYVYSLYQT 532
+ + + A++E + W+GT GL D + K+ER + + + ++SL
Sbjct: 94 TN--NYINAVVEDKNGVFWVGTMNGLNKFDPVTEKFERFYHKENNRTSLSNNKIWSLLID 151
Query: 533 KQGSLYIGTSGSGVLIYDPQTKLFTHY---YTGNCAMISNNIYTILSDEDNEILLST-EN 588
+ L++GT G +++ + FT Y + A+ ++ I D+ + L
Sbjct: 152 RTNKLWVGTD-DGFNLFNKNSNAFTVYQPDFKDPDAIKGKSVNAIAEDKAGNLWLGNWSK 210
Query: 589 GLTSFYPKQKTFYNWTKE 606
GL F K K+F N+T++
Sbjct: 211 GLNKFDKKTKSFKNYTQK 228