Pairwise Alignments
Query, 1420 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Subject, 1365 a.a., hypothetical protein from Pedobacter sp. GW460-11-11-14-LB5
Score = 512 bits (1318), Expect = e-148
Identities = 407/1420 (28%), Positives = 659/1420 (46%), Gaps = 181/1420 (12%)
Query: 87 LKSNFIRNVCEDAFQRLWIVSEGGTDIIDLSTLKPIIPHDPKGILPKILELPATRIMKDT 146
L N + + +D Q +W+ + G + D K I ++ L + + ++ D+
Sbjct: 37 LSQNSVMAITQDKNQFIWMGTRHGLNRYDGYRFK--IYNNSSDNLNSLSDNVINTLLSDS 94
Query: 147 QGCIWLHCDNALHRIEFNDKGE--VQILSTLSPVYLNGPDIALKDIDEDGKIWMGNNGEI 204
+G +W+ +N L+ +NDK + +I S + + D IW+G +
Sbjct: 95 KGRLWVGTENGLNI--YNDKNDHFYRINKRSSANSFSCDSVECIYEDPQKNIWVGTYNGL 152
Query: 205 RKVALSPQKRLVTTPIADCLKFEAGT--YISDFLSKENEVWISSDRGLFR-YNKTGNV-I 260
V + +K++ + D +++ S F ++ +W+ + GL R Y G
Sbjct: 153 NLV-IDTEKQIFKKFLFDKPNYKSALNCIFSIFKDEKQNLWVGTYNGLVRIYQVKGKYHF 211
Query: 261 KRYEHDSGNPYSLSQNYLTNLAITDDKQLIVATLRGINIYNPMTDNFERIACDLPNGGTN 320
+ + H+ N S+S N + ++ I K+L + T G+N+++ F+R + +
Sbjct: 212 EIFRHNPNNKNSISSNAVKSIVIDKQKRLWLGTYNGLNLFDYEHKTFKRYQTSATDPNS- 270
Query: 321 LLNSNFINCILTDGEHIWFGTETGGINLLNPRQLSIRSYRHDKENPSSLSYNPVNAIYED 380
++N++ +IW GT+ G +++L+P +YR+D E P LS N +++I++D
Sbjct: 271 IINNDIRKLTRDKVGNIWIGTQEG-LSILDPNTRKFSNYRYDPEQPDGLSQNSIHSIFQD 329
Query: 381 VYGTLWVGTVEGGLNRKERNSEDFTHY--TREHGGLSHNSVSALTADTDNHLWIGTWGGG 438
+ G++++GT G N ++ FT + ++ GLS + VSA+ D +++LWIGT GGG
Sbjct: 330 LNGSVYLGTYYKGANVVYPSATPFTVFRNSKTRQGLSSDIVSAMVEDQNHNLWIGTEGGG 389
Query: 439 LNLLDLKAPRQILEVISSQTGGGFPINFIGVLNYDPINEGIWIGANQG-LYFYDPVKKEI 497
LN ++ + + G N I L D + + +G ++G LY ++
Sbjct: 390 LNYVNRSNHTFTYYKLEPNSNNGLNSNLIKTLCLDKTGQ-LLVGTHRGGLYLFNAAGHNF 448
Query: 498 TAPLPDKAAENIHG---CIGSIIDKEGKLWVGCLEGV----------------------- 531
+ K +N G I D +G +WVG +G+
Sbjct: 449 KKIINVKNKKNNPGGSEVIAITEDSDGTVWVGSRDGLSTLKKTNGLYAATTVKSPLEQNL 508
Query: 532 ---YIIDLHSRSSK--------GEFQYRHLNYKLD-------DPSSRLIEKITCFYQGKD 573
YI + +K G + Y ++ P S + I C Q ++
Sbjct: 509 RNKYIQVIFEDKAKNLWIGTMAGLYAYHPATKRITAYYKNKTKPGSLNSDHINCIVQIQN 568
Query: 574 GTLWLGSN--GYGIYQRKIDAQGKEQFISYSTAQGLPNNSVRGILEDNNGNLWISTNNGL 631
G + +G++ G I+ K +F +Y+ GLPN++V GI+ED NLWIST+ GL
Sbjct: 569 GNICVGTSFGGLSIFDNK-----SRKFKNYNEKDGLPNSNVLGIIEDEENNLWISTDKGL 623
Query: 632 SCYHQAENRFINYTIQDGLIDTQFYWNASCGSSHDLLYFGSVGGLVA-------IESNRP 684
S RFINYT DGL F + S L+FG GL A I SNR
Sbjct: 624 SKLITKTGRFINYTKSDGLAGNDFNIRSFLKDSRGELFFGGYDGLTAFYPSQIDINSNRN 683
Query: 685 AMSLPAAKVRFTRLRIGNEEILPGSE--YLSEDIAITTELKLHEKEKSFSLEFAALNFES 742
A + FT L++ ++ + + L+EDI ++ +FSL+FA LN+
Sbjct: 684 V-----APITFTELKLFDKPVAVNAPDGLLNEDIKSIKQITFKHDNNNFSLDFALLNYIK 738
Query: 743 NNTAIYSYRLVGFDDKWVQ--VPGNRRFASYTNLPPGSYTLQVRYTPDGENEGENITELK 800
Y Y L G WV+ VP +Y++LP G+YT V + N G LK
Sbjct: 739 PEKNSYRYILKGHSKDWVKTDVPS----VTYSDLPAGNYTFIVTGNNNDGNPGNKPASLK 794
Query: 801 ITIVPYFYKTVWFILFIIVLLSVSVWQFYQWRIRNLKRQKEYLH-RTVEERTHELEQQKH 859
IT++P F+ T W+ ++I L S F R YL R + +RT ++++
Sbjct: 795 ITVLPPFWAT-WWA-YLIYLACFSGLLFLIVR---------YLFVRALLKRTEDIQKM-- 841
Query: 860 LLENQTDELSRQNQMLIQQNEKITRQKAQLIRMSRKVQELTLDKISFFTNITHEFRTPIT 919
K++FFT + HE RTP+T
Sbjct: 842 -------------------------------------------KLNFFTYVAHEIRTPLT 858
Query: 920 LIIGPIERALK-LSYNPQVIEQLNFVERNSKYLLSLVNQLMDFRKVESGKLEIVKTRGNF 978
LI+GP+E K + ++ Q+ ++ N+ L+ L+ +LMDFRK E+G L + T N
Sbjct: 859 LILGPLENLSKQYQTDTELNRQIIPIKNNANRLMRLITELMDFRKAETGHLTLHVTEDNI 918
Query: 979 LKFIDSLITPFEVFAQERNIVLKRYYRMEMPEILYDEEAMRKVVTNLLSNAIKFTPNGGT 1038
+ FI+ + F AQ +I + E + +D+ + KV+ NLLSNA KF GG
Sbjct: 919 VDFINEIFISFSHLAQTNDIQYEFVRGQENISLFFDKRQLEKVLFNLLSNAFKFCDKGGK 978
Query: 1039 VSLYLSALFAKDSEKETLYICVKDSGSGIPEEDLNRIFNRFYQSQNQVKYPVYGQAGTGI 1098
+S+ L + D+E + I + D+G GIP E L +F+ ++Q Q Q G+GI
Sbjct: 979 ISVTLVDM---DNE---VAISIADNGLGIPAESLKNLFSDYFQVDEQHS----NQIGSGI 1028
Query: 1099 GLYLCKRIVQMHGGEIK-----AFNNRHAGCSFRILLPLQRNERKDEKTIIIDHNDSSAT 1153
GL L K IV+ H G I A N +F + L + + KT I D T
Sbjct: 1029 GLALSKAIVEEHKGHIAVESTPAENGERGFTNFTVRL---KKGKSHFKTAIFDGAKDYPT 1085
Query: 1154 PVQDSGSPKEKE-------------ALSILVVEDNADMRGYIRSILREQYHVLEAANGEE 1200
EKE +ILVVEDN+++R I S++ Y V E+ NG
Sbjct: 1086 HPNIYTQQPEKELNILKPEKETDLSTETILVVEDNSEIRQLIASLIGGHYLVAESENGLM 1145
Query: 1201 ALHILNSNPIDFIISDLMMPVMDGIELSRRVKETFAISHIPFLMLTAKTSQEARLESYRM 1260
D II D+MMP+MDGIEL RR+KE SHIP ++LTA++S ++
Sbjct: 1146 GWETAVETLPDLIICDIMMPIMDGIELCRRLKEDERTSHIPVIILTARSSHIHQVSGLET 1205
Query: 1261 GVDEYLLKPFDETLLLARIQNILENRKRYQRKFTLDMDVDVLNMEEESGDKKFLNQVMEV 1320
G D Y+ KPF LLL ++N+L +R+ ++KF + + + + D+ F+ ++++
Sbjct: 1206 GADAYITKPFSPELLLLNVRNLLMSRQVMRQKFLKHIHLQPKELTINAIDEAFMLKLLKY 1265
Query: 1321 IKENYKNSYFEVSDFCEAVGVSKSLLNKKLQNLIGQSAGQFIRNYRLNIARELILKNRET 1380
I E+ + F VS+ VG+S+ +L KK++NL S F+++ RL A EL +NR T
Sbjct: 1266 IDEHITDEDFGVSELASMVGMSRPVLYKKIRNLTNLSVNDFVKSIRLKKAMELFKQNRFT 1325
Query: 1381 KNMNIAEVAYEVGFNDPKYFTRCFTKHFNVTPSALLNNEE 1420
I EVAY+VGFNDPKYF+R F K F +P A +N E
Sbjct: 1326 ----IYEVAYQVGFNDPKYFSREFKKQFGKSPRAFMNGSE 1361
Score = 90.9 bits (224), Expect = 8e-22
Identities = 81/284 (28%), Positives = 130/284 (45%), Gaps = 16/284 (5%)
Query: 367 SSLSYNPVNAIYEDVYGTLWVGTVEGGLNRKE-RNSEDFTHYTREHGGLSHNSVSALTAD 425
+ LS N V AI +D +W+GT GLNR + + + + + LS N ++ L +D
Sbjct: 35 NGLSQNSVMAITQDKNQFIWMGT-RHGLNRYDGYRFKIYNNSSDNLNSLSDNVINTLLSD 93
Query: 426 TDNHLWIGTWGGGLNLLDLKAPRQILEVISSQTGGGFPINFIGVLNYDPINEGIWIGANQ 485
+ LW+GT GLN+ + K + + F + + + DP + IW+G
Sbjct: 94 SKGRLWVGT-ENGLNIYNDKND-HFYRINKRSSANSFSCDSVECIYEDP-QKNIWVGTYN 150
Query: 486 GLYFYDPVKKEITAP-LPDKA-AENIHGCIGSII-DKEGKLWVGCLEGVYIIDLHSRSSK 542
GL +K+I L DK ++ CI SI D++ LWVG G ++ ++ K
Sbjct: 151 GLNLVIDTEKQIFKKFLFDKPNYKSALNCIFSIFKDEKQNLWVGTYNG--LVRIYQVKGK 208
Query: 543 GEFQ-YRHLNYKLDDPSSRLIEKITCFYQGKDGTLWLGS-NGYGIYQRKIDAQGKEQFIS 600
F+ +RH + SS ++ I K LWLG+ NG ++ + + Q S
Sbjct: 209 YHFEIFRHNPNNKNSISSNAVKSIVI---DKQKRLWLGTYNGLNLFDYEHKTFKRYQ-TS 264
Query: 601 YSTAQGLPNNSVRGILEDNNGNLWISTNNGLSCYHQAENRFINY 644
+ + NN +R + D GN+WI T GLS +F NY
Sbjct: 265 ATDPNSIINNDIRKLTRDKVGNIWIGTQEGLSILDPNTRKFSNY 308
Score = 54.7 bits (130), Expect = 6e-11
Identities = 76/363 (20%), Positives = 138/363 (38%), Gaps = 68/363 (18%)
Query: 40 EGLPHNFIDDLYKDSRGFMWISTAGGGLSRYD----GYEFVNYTPNNHQCKLKSNFIRNV 95
+GL + + + +D +WI T GGGL+ + + + PN++ L SN I+ +
Sbjct: 363 QGLSSDIVSAMVEDQNHNLWIGTEGGGLNYVNRSNHTFTYYKLEPNSNN-GLNSNLIKTL 421
Query: 96 CEDAFQRLWI-VSEGGTDIIDLS--TLKPIIPHDPKGILPKILELPATRIMKDTQGCIWL 152
C D +L + GG + + + K II K P E+ A I +D+ G +W+
Sbjct: 422 CLDKTGQLLVGTHRGGLYLFNAAGHNFKKIINVKNKKNNPGGSEVIA--ITEDSDGTVWV 479
Query: 153 HCDNALHRIEFNDKGEVQILSTLSPVYLNGPDIALKDIDEDGKIWMGNNGEIRKVALSPQ 212
+ L ++ G + SP+ N + ++ I ED
Sbjct: 480 GSRDGLSTLK-KTNGLYAATTVKSPLEQNLRNKYIQVIFED------------------- 519
Query: 213 KRLVTTPIADCLKFEAGTYISDFLSKENEVWISSDRGLFRYNKTGNVIKRYEHDSGNPYS 272
K +WI + GL+ Y+ I Y + P S
Sbjct: 520 -------------------------KAKNLWIGTMAGLYAYHPATKRITAYYKNKTKPGS 554
Query: 273 LSQNYLTNLAITDDKQLIVAT-LRGINIYNPMTDNFERIACDLPNGGTNLLNSNFINCIL 331
L+ +++ + + + V T G++I++ + F+ N L NSN + I
Sbjct: 555 LNSDHINCIVQIQNGNICVGTSFGGLSIFDNKSRKFKNY-----NEKDGLPNSNVLGIIE 609
Query: 332 TDGEHIWFGTETGGINLLNPRQLSIRSYRHDKENPSSLSYNPVN--AIYEDVYGTLWVGT 389
+ ++W T+ G L+ I + D L+ N N + +D G L+ G
Sbjct: 610 DEENNLWISTDKGLSKLITKTGRFINYTKSD-----GLAGNDFNIRSFLKDSRGELFFGG 664
Query: 390 VEG 392
+G
Sbjct: 665 YDG 667