Pairwise Alignments
Query, 1060 a.a., bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase from Bifidobacterium breve UCC2003
Subject, 958 a.a., glutamate-ammonia-ligase adenylyltransferase from Caulobacter crescentus NA1000
Score = 138 bits (347), Expect = 2e-36
Identities = 113/371 (30%), Positives = 177/371 (47%), Gaps = 46/371 (12%)
Query: 130 RLLKAVGADPDEPAMPVASKDLAEAATALRSSYRNQLAAIIAQ----DAVAD-----DPT 180
RL + +G DP E + + A AA + R L + A A++D D
Sbjct: 65 RLPRILGGDPGETLAAILAAAEAVAAEPDFETARRVLRELKADLHLLTAISDLGGVWDLD 124
Query: 181 SIQPTISRELSDLADAALEGALAIA----------RHETEGSEHVR--FTIIGMGKLGAQ 228
+ ++R ADA L ALA A H +GS + MGK GA
Sbjct: 125 QVTGALTR----FADAVLHAALAQAVRQEVSRGALTHVGDGSAGPAPGLFCVAMGKHGAF 180
Query: 229 ELNYVSDVD--LIYVVEPVDKDVDHQ---TLIRVGTKMGTMLQRVCQSAIMGVAEQPLWQ 283
ELNY SD+D + Y E + H+ +R+ +G +LQ + +++
Sbjct: 181 ELNYSSDIDFSIFYAPEKLPVAEGHEPQAVAVRIANHLGRILQE-------RTGDGYVFR 233
Query: 284 IDGGLRPEGKDGALVRVLSSHKNYYEQWAENWEFQALLKARPVAGDPDLGQAYMDMTRPF 343
ID LRP+ + + +YYE +NWE A +KAR AGD G A+++ +PF
Sbjct: 234 IDLRLRPDPSSTPPAMPVDAAMDYYESVGQNWERAAHIKARIAAGDAAEGAAFLEGLQPF 293
Query: 344 VWSASKRKNFVYDCQKMRK-----RVEDLIPAPLKDREIKLGRGGLRDVEFTVQMLQLVH 398
+W + + D +++ +V+D + A K ++KLGRGG+R++EF VQ QL+
Sbjct: 294 IWRRNLDFAAIADIHSIKRQIHTYKVDDRLTA--KGADLKLGRGGIREIEFFVQTQQLIL 351
Query: 399 GRTDESLRTSNTLDSLQRLSEGGYVSRKQAVRMSQDYRFERVMEHRQQIWSLKRTHLFP- 457
G LR+ TLD+LQ L+ G+V+ + A ++Q Y+ R +EHR Q+ + +TH P
Sbjct: 352 GGRQPDLRSPRTLDALQALAAAGHVTPEDAAWLTQAYKDLRALEHRAQMIADDQTHKLPE 411
Query: 458 -DLGRASVGGL 467
D+ R V L
Sbjct: 412 SDVERKKVAAL 422
Score = 121 bits (303), Expect = 3e-31
Identities = 106/298 (35%), Positives = 143/298 (47%), Gaps = 21/298 (7%)
Query: 679 EFATSMRAMRRY---EIERIGLSWMSGVISDSDSLKAMTDVYDAIIDASLTWAVRHQIAA 735
+F +M A RR + RIG+ MSG D +A ++ D II L A ++
Sbjct: 609 DFEGAMDAARRLFRDQSFRIGVRVMSGTADARDIGRAFAELADLII-GGLAPAALAEVER 667
Query: 736 FGVETAPAGITVIAMGRYGGREVNFSSDADAILIYRPADDA------DDGQANAFAKKVV 789
G P + V+A+G+ G RE+ SD D + +Y ADD D A F ++
Sbjct: 668 IG-GAFPGQVAVVALGKAGSREMTAKSDLDLMTLY-VADDPRSMSALKDWSAEVFYARLT 725
Query: 790 EDLRNILQGPTTLEPKIELDLDLRPEGKNGPLVRSYASCEEYYESWASTWERQALLRARY 849
+ L + L PT E+DL LRP G GP+ S+A+ E YYE A TWE AL RAR
Sbjct: 726 QRLTSALSAPTGEGTLYEVDLKLRPSGTKGPVAVSFAAFEHYYEREAETWELLALTRARV 785
Query: 850 A-AGDAELARDFLINIADPLRYPTT-ELTEAELQNIRKLKARMEAERLPRGVRRERHLKL 907
A + IA LR P + T A++ +R+L ME ER +G + LKL
Sbjct: 786 VWASSPDFKARAEGAIAAALRRPRAWKKTAADVIEMRQL---MERERPGKG---DWDLKL 839
Query: 908 GKGGLSDVEWTVQLMQLQHASDIKDLRVNGTLEALDVLEAKKLISAIDAIQLRKAWTL 965
GGL D+E+ Q +QL HA+ LR N T EAL L L A +L AW L
Sbjct: 840 DPGGLVDIEFAAQFLQLAHAAADGPLRQN-TGEALAALREAGLADAGALSRLEAAWRL 896
Score = 116 bits (290), Expect = 9e-30
Identities = 94/298 (31%), Positives = 149/298 (50%), Gaps = 15/298 (5%)
Query: 679 EFATSMRAMRRYEIERIGLSWMS--GVISDSDSLK-AMTDVYDAIIDASLTWAVRHQIAA 735
+F T+ R +R + + L+ +S G + D D + A+T DA++ A+L AVR +++
Sbjct: 93 DFETARRVLRELKADLHLLTAISDLGGVWDLDQVTGALTRFADAVLHAALAQAVRQEVSR 152
Query: 736 FGV------ETAPA-GITVIAMGRYGGREVNFSSDADAILIYRPAD--DADDGQANAFAK 786
+ PA G+ +AMG++G E+N+SSD D + Y P A+ + A A
Sbjct: 153 GALTHVGDGSAGPAPGLFCVAMGKHGAFELNYSSDIDFSIFYAPEKLPVAEGHEPQAVAV 212
Query: 787 KVVEDLRNILQGPTTLEPKIELDLDLRPEGKNGPLVRSYASCEEYYESWASTWERQALLR 846
++ L ILQ T +DL LRP+ + P + +YYES WER A ++
Sbjct: 213 RIANHLGRILQERTGDGYVFRIDLRLRPDPSSTPPAMPVDAAMDYYESVGQNWERAAHIK 272
Query: 847 ARYAAGDAELARDFLINIADPLRYPTTELTEAELQNIRKLKARMEAERL-PRGVRRERHL 905
AR AAGDA FL + P + L A + +I +K ++ ++ R + L
Sbjct: 273 ARIAAGDAAEGAAFLEGL-QPFIW-RRNLDFAAIADIHSIKRQIHTYKVDDRLTAKGADL 330
Query: 906 KLGKGGLSDVEWTVQLMQLQHASDIKDLRVNGTLEALDVLEAKKLISAIDAIQLRKAW 963
KLG+GG+ ++E+ VQ QL DLR TL+AL L A ++ DA L +A+
Sbjct: 331 KLGRGGIREIEFFVQTQQLILGGRQPDLRSPRTLDALQALAAAGHVTPEDAAWLTQAY 388
Score = 103 bits (256), Expect = 8e-26
Identities = 107/400 (26%), Positives = 169/400 (42%), Gaps = 45/400 (11%)
Query: 54 PDVALSNFVDIVNAMQSSQRDLKHVIPDNNALKRLVTVLGVSDAMGKFMRFKPQLVEAAA 113
PD A + F D + + S + + + +V V+ + + M +P ++A
Sbjct: 530 PDQAFNRFSDFFSRLSSGVQIQSLFLAQPRLFELIVEVMAFAPRLAATMAKRPTALDA-- 587
Query: 114 VDNCNSHLFNHTQRRARLLKAVGADPDE-PAM-PVASKDLAEAATALRSSYRNQLAAIIA 171
LL P E PA+ P +D A A R +R+Q I
Sbjct: 588 -----------------LLDPTFFGPIETPAIAPWDPEDFEGAMDAARRLFRDQSFRIGV 630
Query: 172 QDAVADDPTSIQPTISRELSDLADAALEGALAIARHETE---GSEHVRFTIIGMGKLGAQ 228
+ T+ I R ++LAD + G A E E G+ + ++ +GK G++
Sbjct: 631 R---VMSGTADARDIGRAFAELADLIIGGLAPAALAEVERIGGAFPGQVAVVALGKAGSR 687
Query: 229 ELNYVSDVDLIYVVEPVDKDVDHQTLIRVGTK---MGTMLQRVCQSAIMGVAEQPLWQID 285
E+ SD+DL+ + V D + ++ + + QR+ + E L+++D
Sbjct: 688 EMTAKSDLDLMTLY--VADDPRSMSALKDWSAEVFYARLTQRLTSALSAPTGEGTLYEVD 745
Query: 286 GGLRPEGKDGALVRVLSSHKNYYEQWAENWEFQALLKARPV-AGDPDL-----GQAYMDM 339
LRP G G + ++ ++YYE+ AE WE AL +AR V A PD G +
Sbjct: 746 LKLRPSGTKGPVAVSFAAFEHYYEREAETWELLALTRARVVWASSPDFKARAEGAIAAAL 805
Query: 340 TRPFVWSASKRKNFVYDCQKMRKRVEDLIPAPLKDREIKLGRGGLRDVEFTVQMLQLVHG 399
RP W K D +MR+ +E P D ++KL GGL D+EF Q LQL H
Sbjct: 806 RRPRAW-----KKTAADVIEMRQLMERERPGK-GDWDLKLDPGGLVDIEFAAQFLQLAHA 859
Query: 400 RTDESLRTSNTLDSLQRLSEGGYVSRKQAVRMSQDYRFER 439
D LR NT ++L L E G R+ +R E+
Sbjct: 860 AADGPLR-QNTGEALAALREAGLADAGALSRLEAAWRLEQ 898