MetaCyc Pathway: L-tyrosine degradation I in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
RR42_RS01570
RR42_RS01590
RR42_RS02275
RR42_RS04465
RR42_RS04985
RR42_RS05770
RR42_RS05990
RR42_RS09190
RR42_RS09965
RR42_RS10785
RR42_RS12545
RR42_RS14560
RR42_RS15580
RR42_RS16470
RR42_RS18910
RR42_RS21340
RR42_RS25980
RR42_RS26005
RR42_RS26015
RR42_RS26185
RR42_RS26625
RR42_RS28185
RR42_RS32165
RR42_RS33140
RR42_RS33490
RR42_RS33805
RR42_RS35305
RR42_RS36780
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)
RR42_RS32440
RR42_RS32485
RR42_RS33500
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)
RR42_RS31275
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)
RR42_RS00915
RR42_RS01970
RR42_RS30510
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)
RR42_RS01965
RR42_RS09905
RR42_RS30515
RR42_RS31270

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information