MetaCyc Pathway: poly(glycerol phosphate) wall teichoic acid biosynthesis in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Glycerol-3-phosphate cytidylyltransferase:
sn-glycerol 3-phosphate + CTP + H+→(2R)-CDP-glycerol + diphosphate (EC 2.7.7.39)
RR42_RS00710
di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-α-D-glucosamine→α-D-GlcNAc-PP-Und + UMP (EC 2.7.8.33)
No genes
D-alanine + ATP + a holo [D-alanyl carrier protein]→a D-alanyl-[D-alanyl carrier protein] + AMP + diphosphate (EC 6.2.1.54)
No genes
a D-alanyl-[D-alanyl carrier protein] + a phosphatidylglycerol[membrane]→2-O-D-alanyl-1-O-phosphatidylglycerol[out] + a holo [D-alanyl carrier protein][in] (EC 2.3.2.M5)
No genes
mannosaminyltransferase:
α-D-GlcNAc-PP-Und + UDP-N-acetyl-α-D-mannosamine→β-D-ManNAc-(1→4)-α-D-GlcNAc-PP-Und + H+ + UDP (EC 2.4.1.187)
RR42_RS33210
β-D-ManNAc-(1→4)-α-D-GlcNAc-PP-Und + (2R)-CDP-glycerol→Gro-P-β-D-ManNAc-(1→4)-α-D-GlcNAc-PP-Und + CMP + H+ (EC 2.7.8.44)
No genes
CDP-glycerol glycerophosphotransferase:
Gro-P-β-D-ManNAc-(1→4)-α-D-GlcNAc-PP-Und + n (2R)-CDP-glycerol→(Gro-P)n-Gro-P-ManNAc-GlcNAc-PP-undecaprenol + n CMP (EC 2.7.8.12)
No genes
Poly(glycerol-phosphate) alpha-glucosyltransferase:
(Gro-P)n-Gro-P-ManNAc-GlcNAc-PP-undecaprenol + n UDP-α-D-glucose→[(2-Glc)-Gro-P]n-Gro-P-ManNAc-GlcNAc-PP-undecaprenol + n H+ + n UDP (EC 2.4.1.52)
No genes
[(2-Glc)-Gro-P]n-Gro-P-ManNAc-GlcNAc-PP-undecaprenol[in] + ATP[in] + H2O[in]→[(2-Glc)-Gro-P]n-Gro-P-ManNAc-GlcNAc-PP-undecaprenol[out] + ADP[in] + H+[in] + phosphate[in] (EC 7.5.2.4)
No genes
2-O-D-alanyl-1-O-phosphatidylglycerol + [(2-Glc)-Gro-P]n-Gro-P-ManNAc-GlcNAc-PP-undecaprenol→a polyisoprenyl-major wall teichoic acid (B. subtilis 168) + a phosphatidylglycerol (EC 2.3.1.M32)
No genes
a polyisoprenyl-major wall teichoic acid (B. subtilis 168) + Und-PP-[β-D-GlcNAc-(1→4)]-MurNAc-L-Ala-γ-D-Glu-meso-DAP-D-Ala-D-Ala + H2O→di-trans,octa-cis-undecaprenyl phosphate + a peptidoglycan-major wall teichoic acid complex (B. subtilis 168) + 2 H+ + di-trans,octa-cis-undecaprenyl diphosphate (EC 2.7.8.M1)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information