MetaCyc Pathway: superpathway of L-serine and glycine biosynthesis I in Cupriavidus basilensis FW507-4G11

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Phosphoglycerate dehydrogenase:
3-phospho-D-glycerate + NAD+→3-phosphooxypyruvate + NADH + H+ (EC 1.1.1.95)
RR42_RS00950
RR42_RS02235
RR42_RS03865
RR42_RS05155
RR42_RS10510
RR42_RS10615
RR42_RS10620
RR42_RS20535
RR42_RS26540
RR42_RS27010
RR42_RS27410
RR42_RS33330
RR42_RS33660
RR42_RS34610
RR42_RS37380
Phosphoserine transaminase (in reverse):
3-phosphooxypyruvate + L-glutamate→O-phospho-L-serine + 2-oxoglutarate (EC 2.6.1.52)
RR42_RS04455
Phosphoserine phosphatase:
O-phospho-L-serine + H2O→L-serine + phosphate (EC 3.1.3.3)
RR42_RS07660
RR42_RS17230
RR42_RS21330
RR42_RS28245
Glycine hydroxymethyltransferase:
L-serine + a tetrahydrofolate→glycine + a 5,10-methylenetetrahydrofolate + H2O (EC 2.1.2.1)
RR42_RS15485

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information