MetaCyc Pathway: pyruvate decarboxylation to acetyl CoA I in Cupriavidus basilensis FW507-4G11

a [pyruvate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine + NAD+→a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine + NADH + H+ (EC 1.2.1.104; 1.8.1.4)

RR42_RS07380

RR42_RS12930

RR42_RS21770

RR42_RS26115

RR42_RS34380

a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine + pyruvate + H+→a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine + CO2 (EC 1.2.1.104; 1.2.4.1)

RR42_RS07365

RR42_RS10655

RR42_RS10660

RR42_RS21725

RR42_RS21730

RR42_RS24415

RR42_RS26125

RR42_RS29920

RR42_RS32980

RR42_RS33045

RR42_RS33050

RR42_RS34220

a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine + coenzyme A→a [pyruvate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine + acetyl-CoA (EC 1.2.1.104; 2.3.1.12)

RR42_RS07370

RR42_RS10665

RR42_RS21735

RR42_RS21775

RR42_RS26120

RR42_RS33055

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information