MetaCyc Pathway: NAD salvage pathway I (PNC VI cycle) in Cupriavidus basilensis FW507-4G11

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NAD(+) synthase (glutamine-hydrolyzing):
nicotinate adenine dinucleotide + ATP + L-glutamine + H2O→NAD+ + AMP + L-glutamate + diphosphate + H+ (EC 6.3.5.1)
RR42_RS35170
NAD(+) diphosphatase:
NAD+ + H2O→β-nicotinamide D-ribonucleotide + AMP + 2 H+ (EC 3.6.1.22)
RR42_RS11905
NMN nucleosidase:
β-nicotinamide D-ribonucleotide + H2O→nicotinamide + D-ribofuranose 5-phosphate + H+ (EC 3.2.2.14; 3.2.2.6)
No genes
Nicotinamidase:
nicotinamide + H2O→nicotinate + ammonium (EC 3.5.1.19)
RR42_RS11090
nicotinate + ATP + 5-phospho-α-D-ribose 1-diphosphate + H2O→β-nicotinate D-ribonucleotide + ADP + diphosphate + phosphate (EC 6.3.4.21)
RR42_RS14205
Nicotinate-nucleotide adenylyltransferase:
β-nicotinate D-ribonucleotide + ATP + H+→nicotinate adenine dinucleotide + diphosphate (EC 2.7.7.18)
RR42_RS04720
NAD(+) synthase:
nicotinate adenine dinucleotide + ammonium + ATP→NAD+ + AMP + diphosphate + H+ (EC 6.3.1.5)
RR42_RS35170

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information