MetaCyc Pathway: 3-methyl-branched fatty acid α-oxidation in Cupriavidus basilensis FW507-4G11

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Long-chain-fatty-acid--CoA ligase:
a 3-methyl-branched 2,3,4-saturated fatty acid + ATP + coenzyme A→a 3-methyl-branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate
(EC 6.2.1.3)
RR42_RS01625
RR42_RS18150
RR42_RS18540
RR42_RS25195
RR42_RS26915
RR42_RS28980
RR42_RS29035
RR42_RS29460
RR42_RS29475
RR42_RS36095
RR42_RS36385
RR42_RS36505
a 3-methyl-branched 2,3,4-saturated fatty acyl-CoA + 2-oxoglutarate + dioxygen→a 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA + CO2 + succinate
No genes
a 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA→a 2-methyl branched 2,3,4-saturated fatty aldehyde + formyl-CoA (EC 4.1.2.63)
No genes
Formyl-CoA hydrolase:
formyl-CoA + H2O→formate + coenzyme A + H+
(EC 3.1.2.10)
No genes
Aldehyde dehydrogenase (NAD(+)):
a 2-methyl branched 2,3,4-saturated fatty aldehyde + NAD+ + H2O→a 2-methyl branched 2,3,4-saturated fatty acid + NADH + 2 H+
(EC 1.2.1.3)
RR42_RS01275
RR42_RS04280
RR42_RS11360
RR42_RS13660
RR42_RS18500
RR42_RS21485
RR42_RS23750
RR42_RS24065
RR42_RS24390
RR42_RS24705
RR42_RS24840
RR42_RS25005
RR42_RS25010
RR42_RS26255
RR42_RS27350
RR42_RS27780
RR42_RS29955
RR42_RS32140
RR42_RS34255
Long-chain-fatty-acid--CoA ligase:
a 2-methyl branched 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2-methyl branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate
(EC 6.2.1.3)
RR42_RS01625
RR42_RS18150
RR42_RS18540
RR42_RS25195
RR42_RS26915
RR42_RS28980
RR42_RS29035
RR42_RS29460
RR42_RS29475
RR42_RS36095
RR42_RS36385
RR42_RS36505

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information