MetaCyc Pathway: biphenyl degradation in Cupriavidus basilensis FW507-4G11

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Biphenyl 2,3-dioxygenase:
biphenyl + NADH + dioxygen + H+→cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+
(EC 1.14.12.18)
No genes
Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase:
cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+→biphenyl-2,3-diol + NADH + H+
(EC 1.3.1.56)
No genes
Biphenyl-2,3-diol 1,2-dioxygenase:
biphenyl-2,3-diol + dioxygen→2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H+
(EC 1.13.11.39)
RR42_RS05145
RR42_RS31960
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate→2,6-dioxo-6-phenylhexa-3-enoate (spontaneous)
No genes
2,6-dioxo-6-phenylhexa-3-enoate hydrolase:
2,6-dioxo-6-phenylhexa-3-enoate + H2O→benzoate + (2Z)-2-hydroxypenta-2,4-dienoate + H+
(EC 3.7.1.8)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information