MetaCyc Pathway: stearate biosynthesis III (fungi) in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Fatty-acyl-CoA synthase:
a palmitoyl-[acp domain within a fatty acid synthase] + malonyl-CoA + H+→a 3-oxooctadecanoyl-[acp domain within a fatty acid synthase] + CO2 + coenzyme A (EC 2.3.1.86)
No genes
Fatty-acyl-CoA synthase (in reverse):
a 3-oxooctadecanoyl-[acp domain within a fatty acid synthase] + NADPH + H+→a (3R)-3-hydroxyoctadecanoyl-[acp domain within a fatty acid synthase] + NADP+ (EC 2.3.1.86)
No genes
Fatty-acyl-CoA synthase:
a (3R)-3-hydroxyoctadecanoyl-[acp domain within a fatty acid synthase]→a (2E)-octadec-2-enoyl-[acp domain within a fatty acid synthase] + H2O (EC 2.3.1.86)
No genes
Fatty-acyl-CoA synthase (in reverse):
a (2E)-octadec-2-enoyl-[acp domain within a fatty acid synthase] + NADPH + H+→a stearoyl-[acp domain within a fatty acid synthase] + NADP+ (EC 2.3.1.86)
No genes
Fatty-acyl-CoA synthase:
a stearoyl-[acp domain within a fatty acid synthase] + coenzyme A→stearoyl-CoA + an [acyl carrier protein] domain within a fatty acid synthase (EC 2.3.1.86)
No genes
Palmitoyl-CoA hydrolase:
stearoyl-CoA + H2O→stearate + coenzyme A + H+ (EC 3.1.2.2)
RR42_RS10830

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information