MetaCyc Pathway: flavonoid biosynthesis in Cupriavidus basilensis FW507-4G11

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4-coumarate--CoA ligase:
4-coumarate + ATP + coenzyme A→(E)-4-coumaroyl-CoA + AMP + diphosphate (EC 6.2.1.12)
RR42_RS36410
Naringenin-chalcone synthase:
(E)-4-coumaroyl-CoA + 3 malonyl-CoA + 3 H+→naringenin chalcone + 3 CO2 + 4 coenzyme A (EC 2.3.1.74)
No genes
6'-deoxychalcone synthase:
(E)-4-coumaroyl-CoA + 3 malonyl-CoA + NADPH + 4 H+→isoliquiritigenin + 3 CO2 + 4 coenzyme A + NADP+ + H2O (EC 2.3.1.170)
No genes
Chalcone isomerase:
naringenin chalcone→(2S)-naringenin (EC 5.5.1.6)
No genes
Flavanone 3-dioxygenase:
(2S)-naringenin + 2-oxoglutarate + dioxygen→(+)-dihydrokaempferol + CO2 + succinate (EC 1.14.11.9)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information