MetaCyc Pathway: superpathway of L-alanine biosynthesis in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Alanine transaminase (in reverse):
pyruvate + L-glutamate→L-alanine + 2-oxoglutarate
(EC 2.6.1.2)
RR42_RS12545
RR42_RS28540
Branched-chain-amino-acid transaminase (in reverse):
3-methyl-2-oxobutanoate + L-glutamate→L-valine + 2-oxoglutarate
(EC 2.6.1.42)
RR42_RS25890
Cysteine desulfurase:
L-cysteine + an unsulfurated [sulfur carrier]→L-alanine + a sulfurated [sulfur carrier]
(EC 2.8.1.7)
RR42_RS06025
RR42_RS21580
RR42_RS26680
RR42_RS26805
RR42_RS34005
Valine--pyruvate transaminase:
L-valine + pyruvate→3-methyl-2-oxobutanoate + L-alanine
(EC 2.6.1.66)
RR42_RS12545
RR42_RS14595

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information