MetaCyc Pathway: 2-allylmalonyl-CoA biosynthesis in Cupriavidus basilensis FW507-4G11

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propanoyl-CoA + TcsB polyketide synthase→propanoyl-[TcsB polyketide synthase] + coenzyme A
No genes
malonyl-CoA + TcsA polyketide synthase→malonyl-[TcsA polyketide synthase] + coenzyme A
No genes
malonyl-[TcsA polyketide synthase] + propanoyl-[TcsB polyketide synthase] + H+→3-oxopentanoyl-[TcsA polyketide synthase] + CO2 + TcsB polyketide synthase
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
3-oxopentanoyl-[TcsA polyketide synthase] + NADPH + H+→(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase] + NADP+ (EC 1.1.1.100)
RR42_RS04765
RR42_RS08710
RR42_RS09330
RR42_RS10255
RR42_RS10315
RR42_RS10320
RR42_RS11070
RR42_RS11550
RR42_RS13675
RR42_RS13690
RR42_RS14100
RR42_RS16365
RR42_RS16375
RR42_RS16800
RR42_RS17660
RR42_RS21765
RR42_RS21790
RR42_RS21865
RR42_RS22390
RR42_RS22710
RR42_RS22740
RR42_RS22810
RR42_RS23420
RR42_RS23690
RR42_RS24195
RR42_RS25125
RR42_RS25495
RR42_RS28045
RR42_RS28985
RR42_RS29305
RR42_RS31190
RR42_RS31670
RR42_RS31820
RR42_RS31835
RR42_RS31900
RR42_RS33070
RR42_RS33710
RR42_RS34680
RR42_RS35910
RR42_RS36415
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase]→(2E)-pent-2-enoyl-[TcsA polyketide synthase] + H2O (EC 4.2.1.59)
RR42_RS11820
(2E)-pent-2-enoyl-[TcsA polyketide synthase] + CO2 + NADPH→2-carboxypentanoyl-[TcsA polyketide synthase] + NADP+
No genes
2-carboxypentanoyl-[TcsA polyketide synthase] + FAD + H+→2-allylmalonyl-[TcsA polyketide synthase] + FADH2
No genes
2-allylmalonyl-[TcsA polyketide synthase] + coenzyme A→2-allylmalonyl-CoA + TcsA polyketide synthase
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information