MetaCyc Pathway: (2S)-ethylmalonyl-CoA biosynthesis in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
RR42_RS00885
RR42_RS02515
RR42_RS03010
RR42_RS07610
RR42_RS07645
RR42_RS10260
RR42_RS10540
RR42_RS11085
RR42_RS16595
RR42_RS22625
RR42_RS24300
RR42_RS24970
RR42_RS25210
RR42_RS25380
RR42_RS25455
RR42_RS26090
RR42_RS27160
RR42_RS27235
RR42_RS28055
RR42_RS28390
RR42_RS31890
RR42_RS31920
RR42_RS35915
RR42_RS36320
RR42_RS37020
Acetoacetyl-CoA reductase (in reverse):
acetoacetyl-CoA + NADPH + H+→(3R)-3-hydroxybutanoyl-CoA + NADP+ (EC 1.1.1.36)
RR42_RS07615
RR42_RS26085
3-hydroxybutyryl-CoA dehydratase:
(3R)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.55)
No genes
crotonyl-CoA + CO2 + NADPH→(2S)-ethylmalonyl-CoA + NADP+ (EC 1.3.1.85)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information