MetaCyc Pathway: dTDP-sibirosamine biosynthesis in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Glucose-1-phosphate thymidylyltransferase:
α-D-glucopyranose 1-phosphate + H+ + dTTP→dTDP-α-D-glucose + diphosphate (EC 2.7.7.24)
RR42_RS02750
dTDP-glucose 4,6-dehydratase:
dTDP-α-D-glucose→dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + H2O (EC 4.2.1.46)
RR42_RS15815
RR42_RS15840
RR42_RS16435
RR42_RS23585
dTDP-4-dehydrorhamnose 3,5-epimerase:
dTDP-4-dehydro-6-deoxy-α-D-glucopyranose→dTDP-4-dehydro-β-L-rhamnose (EC 5.1.3.13)
RR42_RS15830
RR42_RS23595
dTDP-4-dehydro-β-L-rhamnose + S-adenosyl-L-methionine→dTDP-4-dehydro-3-methyl-β-L-rhamnose + S-adenosyl-L-homocysteine + H+
No genes
dTDP-4-dehydro-3-methyl-β-L-rhamnose + L-glutamate→dTDP-4-amino-4-deoxy-3-methyl-β-L-rhamnose + 2-oxoglutarate
No genes
dTDP-4-amino-4-deoxy-3-methyl-β-L-rhamnose + S-adenosyl-L-methionine→dTDP-sibirosamine + S-adenosyl-L-homocysteine + H+
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information