MetaCyc Pathway: dZTP biosynthesis in Cupriavidus basilensis FW507-4G11

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Nucleotide diphosphatase:
dGTP + H2O→dGMP + diphosphate + H+ (EC 3.6.1.9; 3.6.1.M7)
No genes
dGMP + ATP + L-aspartate→2-amino-2'-deoxy-N6-[(2S)-succino]adenylate + ADP + 2 H+ + phosphate (EC 6.3.4.25)
No genes
Adenylosuccinate lyase:
2-amino-2'-deoxy-N6-[(2S)-succino]adenylate→dZMP + fumarate (EC 4.3.2.2)
RR42_RS17455
Guanylate kinase:
dZMP + ATP→dZDP + ADP (EC 2.7.4.8)
RR42_RS04905
RR42_RS04910
RR42_RS28065
Nucleoside-diphosphate kinase:
dZDP + ATP→dZTP + ADP (EC 2.7.4.6)
RR42_RS13160

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information