MetaCyc Pathway: Entner-Doudoroff pathway I in Cupriavidus basilensis FW507-4G11

Glucose-6-phosphate dehydrogenase: D-glucopyranose 6-phosphate + NADP+→6-phospho D-glucono-1,5-lactone + NADPH + H+ (EC 1.1.1.49)

RR42_RS03375

RR42_RS37405

6-phosphogluconolactonase: 6-phospho D-glucono-1,5-lactone + H2O→D-gluconate 6-phosphate + H+ (EC 3.1.1.31)

RR42_RS37400

Phosphogluconate dehydratase: D-gluconate 6-phosphate→2-dehydro-3-deoxy-D-gluconate 6-phosphate + H2O (EC 4.2.1.12)

RR42_RS06125

RR42_RS37440

2-dehydro-3-deoxy-phosphogluconate aldolase: 2-dehydro-3-deoxy-D-gluconate 6-phosphate→D-glyceraldehyde 3-phosphate + pyruvate (EC 4.1.2.14; 4.1.2.55)

RR42_RS28865

Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating): D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)

RR42_RS17570

Phosphoglycerate kinase (in reverse): 3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)

RR42_RS03200

3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.11)

RR42_RS01825

Phosphopyruvate hydratase: 2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)

RR42_RS06175

RR42_RS33730

Pyruvate kinase (in reverse): phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)

RR42_RS03210

RR42_RS19870

RR42_RS33735

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information