MetaCyc Pathway: trans-caffeate degradation (aerobic) in Cupriavidus basilensis FW507-4G11

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4-coumarate--CoA ligase:
trans-caffeate + ATP + coenzyme A→(E)-caffeoyl-CoA + AMP + diphosphate (EC 6.2.1.12)
RR42_RS36410
(E)-caffeoyl-CoA + H2O→3-(3,4-dihydroxyphenyl)-3-hydroxypropanoate (EC 4.1.2.61)
No genes
3-(3,4-dihydroxyphenyl)-3-hydroxypropanoate→3,4-dihydroxybenzaldehyde + acetyl-CoA (EC 4.1.2.61)
No genes
Vanillin dehydrogenase:
3,4-dihydroxybenzaldehyde + NAD(P)+ + H2O→protocatechuate + NAD(P)H + 2 H+ (EC 1.2.1.67)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information