MetaCyc Pathway: 4-coumarate degradation (aerobic) in Cupriavidus basilensis FW507-4G11

Add experiment(s):


4-coumarate--CoA ligase:
4-coumarate + ATP + coenzyme A→(E)-4-coumaroyl-CoA + AMP + diphosphate (EC 6.2.1.12)
RR42_RS36410
(E)-4-coumaroyl-CoA + H2O→3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA (EC 4.1.2.61)
No genes
3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA→4-hydroxybenzaldehyde + acetyl-CoA (EC 4.1.2.61)
No genes
Vanillin dehydrogenase:
4-hydroxybenzaldehyde + NAD(P)+ + H2O→4-hydroxybenzoate + NAD(P)H + 2 H+ (EC 1.2.1.67)
No genes
4-hydroxybenzoate 3-monooxygenase:
4-hydroxybenzoate + NADPH + dioxygen + H+→protocatechuate + NADP+ + H2O (EC 1.14.13.2)
RR42_RS21940

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information