MetaCyc Pathway: superpathway of menaquinol-8 biosynthesis III in Cupriavidus basilensis FW507-4G11

Add experiment(s):


chorismate→3-[(1-carboxyvinyl)oxy]benzoate + H2O (EC 4.2.1.151)
No genes
(2E,6E)-farnesyl diphosphate + 5 3-methylbut-3-en-1-yl diphosphate→all-trans-octaprenyl diphosphate + 5 diphosphate (EC 2.5.1.90)
RR42_RS15010
RR42_RS17960
3-[(1-carboxyvinyl)oxy]benzoate + S-adenosyl-L-methionine + H2O→6-amino-6-deoxyfutalosine + hydrogen carbonate + L-methionine + H+ (EC 2.5.1.120)
No genes
6-amino-6-deoxyfutalosine + H2O→dehypoxanthine futalosine + adenine (EC 3.2.2.30)
No genes
dehypoxanthine futalosine + S-adenosyl-L-methionine→cyclic dehypoxanthine futalosine + 5'-deoxyadenosine + L-methionine + H+ (EC 1.21.98.1)
No genes
cyclic dehypoxanthine futalosine→1,4-dihydroxy-6-naphthoate + dihydroxyacetone (EC 4.1.99.M7)
No genes
1,4-dihydroxy-6-naphthoate + all-trans-octaprenyl diphosphate→6-carboxy-2-demethylmenaquinol-8 + diphosphate (EC 2.5.1.M27)
No genes
6-carboxy-2-demethylmenaquinol-8 + H+→demethylmenaquinol-8 + CO2 (EC 4.1.1.M24)
No genes
demethylmenaquinol-8 + S-adenosyl-L-methionine→menaquinol-8 + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.163)
RR42_RS02400

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information