4-coumarate--CoA ligase:
4-coumarate + ATP + coenzyme A→(E)-4-coumaroyl-CoA + AMP + diphosphate (EC 6.2.1.12) |
| RR42_RS36410 |
Naringenin-chalcone synthase:
(E)-4-coumaroyl-CoA + 3 malonyl-CoA + 3 H+→naringenin chalcone + 3 CO2 + 4 coenzyme A (EC 2.3.1.74) |
| No genes |
| (E)-4-coumaroyl-CoA + NADPH + H+→dihydro-4-coumaroyl-CoA + NADP+ (EC 1.3.1.117) |
| No genes |
Chalcone isomerase:
naringenin chalcone→(2S)-naringenin (EC 5.5.1.6) |
| No genes |
Naringenin-chalcone synthase:
dihydro-4-coumaroyl-CoA + 3 malonyl-CoA + 3 H+→phloretin + 3 CO2 + 4 coenzyme A (EC 2.3.1.74) |
| No genes |
| (2S)-naringenin + dioxygen + a reduced [NADPH-hemoprotein reductase]→2-hydroxynaringenin + an oxidized [NADPH-hemoprotein reductase] + H+ + H2O (EC 1.14.14.162) |
| No genes |
| phloretin + UDP-α-D-glucose→nothofagin + H+ + UDP (EC 2.4.1.360) |
| No genes |
| 2-hydroxynaringenin→1-(4-hydroxyphenyl)-3-(2,4,6-trihydroxyphenyl)propane-1,3-dione (spontaneous) |
| No genes |
| nothofagin + UDP-α-D-glucose→3',5'-di-C-glucosylphloretin + H+ + UDP |
| No genes |
| 1-(4-hydroxyphenyl)-3-(2,4,6-trihydroxyphenyl)propane-1,3-dione + UDP-α-D-glucose→3-C-glucosyl-2,4,4',6-tetrahydroxydibenzoylmethane + H+ + UDP (EC 2.4.1.360) |
| No genes |
| 3-C-glucosyl-2,4,4',6-tetrahydroxydibenzoylmethane→vitexin + H2O (EC 4.2.1.M14) |
| No genes |
| 3-C-glucosyl-2,4,4',6-tetrahydroxydibenzoylmethane→isovitexin + H2O (EC 4.2.1.M14) |
| No genes |
| 3-C-glucosyl-2,4,4',6-tetrahydroxydibenzoylmethane + UDP-α-D-glucose→3,5-di-C-glucosyl-2,4,4',6-tetrahydroxydibenzoylmethane + H+ + UDP |
| No genes |
| 3-C-glucosyl-2,4,4',6-tetrahydroxydibenzoylmethane→6-C-glucosyl-2-hydroxynaringenin (spontaneous) |
| No genes |
| 3,5-di-C-glucosyl-2,4,4',6-tetrahydroxydibenzoylmethane→vicenin-2 + H2O (EC 4.2.1.M14) |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information