MetaCyc Pathway: neolacto-series glycosphingolipids biosynthesis in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Ceramide glucosyltransferase:
an N-acylsphingosine + UDP-α-D-glucose→a β-D-glucosyl-N-acylsphingosine + H+ + UDP
(EC 2.4.1.80)
RR42_RS35290
a β-D-glucosyl-N-acylsphingosine + UDP-α-D-galactose→a lactosylceramide + H+ + UDP (EC 2.4.1.274)
No genes
Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase:
a lactosylceramide + UDP-N-acetyl-α-D-glucosamine→a lactotriaosylceramide + H+ + UDP
(EC 2.4.1.206)
No genes
a lactotriaosylceramide + UDP-α-D-galactose→a neolactotetraosylceramide + H+ + UDP (EC 2.4.1.275)
No genes
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase:
a neolactotetraosylceramide + UDP-N-acetyl-α-D-glucosamine→a neolactopentaosylceramide + H+ + UDP
(EC 2.4.1.149)
No genes
a neolactotetraosylceramide + CMP-N-acetyl-β-neuraminate→a ganglioside LM1 + CMP + H+ (EC 2.4.3.6)
No genes
a neolactotetraosylceramide + CMP-N-acetyl-β-neuraminate→a ganglioside 6'-LM1 + CMP + H+ (EC 2.4.3.1)
No genes
a neolactopentaosylceramide + UDP-α-D-galactose→a neolactohexaosylceramide + H+ + UDP (EC 2.4.1.275)
No genes
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase:
a neolactohexaosylceramide + UDP-N-acetyl-α-D-glucosamine→a neolactoheptaosylceramide + H+ + UDP
(EC 2.4.1.149)
No genes
a neolactohexaosylceramide + CMP-N-acetyl-β-neuraminate→a sialyl-(2,3)-neolactohexaosylceramide + CMP + H+ (EC 2.4.3.6)
No genes
a neolactoheptaosylceramide + UDP-α-D-galactose→a neolactooctaosylceramide + H+ + UDP (EC 2.4.1.275)
No genes
a neolactooctaosylceramide + CMP-N-acetyl-β-neuraminate→a sialyl-(2,3)-neolactoheptaosylceramide + CMP + H+ (EC 2.4.3.6)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information